Pyrimethamine (Daraprim)
Ndinaya
Daraprim bụ ọgwụ antimalarial nke na-eji pyrimethamine dị ka ihe na-arụ ọrụ, na-enwe ike igbochi mmepụta nke enzymes site na protozoan maka ịba, si otú a na-agwọ ọrịa ahụ.
Enwere ike ịzụta daraprim site na ụlọ ahịa ọgwụ ndị nwere ọgwụ na ndenye ọgwụ n'ụdị igbe nwere mbadamba 100 nke 25 mg.
Ahịa
Ọnụahịa nke Daraprim bụ ihe dịka 7 reais, ma ego ọ nwere ike ịdị iche dịka ebe a zụrụ ọgwụ ahụ.
Ihe ngosi
A na-egosi daraprim maka igbochi na ọgwụgwọ ịba, yana ọgwụ ndị ọzọ. Na mgbakwunye, enwere ike iji Daraprim gwọọ Toxoplasmosis, dịka ihe dọkịta kwuru.
Olee otú iji
Otu esi eji Daraprim dị iche iche dịka ebumnuche ọgwụgwọ na afọ nke onye ọrịa, yana ntuziaka izugbe gụnyere:
Mgbochi ịba
- Okenye na ụmụaka karịrị afọ 10: 1 mbadamba kwa izu;
- Agedmụaka gbara afọ 5 ruo 10: ½ mbadamba kwa izu;
- Undermụaka nọ n'okpuru 5: ¼ mbadamba otu izu.
Ọgwụgwọ ịba
- Okenye na ụmụaka karịrị afọ 14: Mbadamba 2 ruo 3 na 1000 mg na 1500 mg nke sulfadiazine na otu mkpụrụ ọgwụ;
- Agedmụaka dị afọ 9 ruo 14: Mbadamba 2 tinyere 1000 mg nke sulfadiazine n'otu mkpụrụ;
- Agedmụaka dị afọ 4 ruo 8: 1 mbadamba tinyere 1000 mg nke sulfadiazine n'otu mkpụrụ;
- Undermụaka nọ n'okpuru afọ 4: ½ mbadamba tinyere 1000 mg nke sulfadiazine n'otu mkpụrụ.
Mmetụta dị n'akụkụ
Mmetụta utịp dị na Daraprim gụnyere nsị anụ ahụ, palpitations, ọgbụgbọ, ọnya afọ ọsịsa, afọ ọsịsa, enweghị agụụ nri, ọbara na mmamịrị na mgbanwe n'ọbara ọbara.
Nkwekọrịta
A machibidoro Daraprim na ndị ọrịa nwere anaemia nke megaloblastic nke abụọ n'ihi ụkọ nri ma ọ bụ oke mmetụta nke pyrimethamine ma ọ bụ ihe ọ bụla nke usoro ahụ.