Odee: Joan Hall
OfbọChị Okike: 6 Februari 2021
DatebọChị Mmelite: 3 Novemba 2024
Anonim
Thyroid hormone synthesis, regulation and mechanism of action
Vidio: Thyroid hormone synthesis, regulation and mechanism of action

Ndinaya

Kedu ihe bụ thyroxine (T4) ule?

Nnwale nke thyroxine na-enyere aka ịchọpụta nsogbu nke thyroid. The thyroid bụ obere, nru ububa-yiri gland dị nso na akpịrị. Gị thyroid na-eme ka homonụ na-achịkwa ụzọ ahụ gị si eji ike. Ọ na-arụ ọrụ dị mkpa n'ịchịkwa ịdị arọ gị, okpomọkụ ahụ gị, ike ahụ ike gị, na ọbụna ọnọdụ gị. Thyroxine, makwaara dị ka T4, bụ ụdị thyroid hormone. Nnwale a tụọ ogo nke T4 n'ọbara gị. Oke ma ọ bụ obere T4 nwere ike igosi ọrịa thyroid.

T4 hormone dị n'ụdị abụọ:

  • Free T4, nke na-abanye n'ime anụ ahụ ebe ọ dị mkpa
  • Daalụ T4, nke na-arapara na protein, na-egbochi ya ịbanye na anụ ahụ

Nnwale nke na-atụle ma n'efu ma kewaa T4 ka a na-akpọ ngụkọta T4 ule. Nlere ndị ọzọ na-atụle T4 n'efu. A na-ewere nyocha T4 n'efu ka ọ bụrụ ihe ziri ezi karịa ngụkọta T4 nyocha maka ịlele ọrụ thyroid.

Aha ndị ọzọ: free thyroxine, free T4, ngụkọta T4 ịta ahụhụ, thyroxine ihuenyo, free T4 ịta


Kedu ihe eji ya?

A na-eji T4 nwalee iji nyochaa ọrụ thyroid na ịchọpụta ọrịa thyroid.

Kedu ihe kpatara m ji chọọ nyocha thyroxine?

Ọrịa thyroid gị bụ ihe a na-ahụkarị na ụmụ nwanyị ma na-apụtakarị n'okpuru afọ 40. Ọ na-agbasakwa na ezinụlọ. Nwere ike ịchọ nyocha nke thyroxine ma ọ bụrụ na onye ezinụlọ gị enweela ọrịa thyroid ma ọ bụ ọ bụrụ na ị nwere mgbaàmà nke inwe ọtụtụ thyroid hormone n'ọbara gị, ọnọdụ a na-akpọ hyperthyroidism, ma ọ bụ ihe mgbaàmà nke inwe obere thyroid hormone, ọnọdụ a na-akpọ hypothyroidism.

Mgbaàmà nke hyperthyroidism, nke a makwaara dị ka thyroid na-arụ ọrụ, gụnyere:

  • Nchegbu
  • Iwetulata ibu
  • Trema jijiji na aka
  • Enwekwu obi uto
  • Afụli
  • Bulging nke anya
  • Nsogbu ihi ụra

Mgbaàmà nke hypothyroidism, nke a makwaara dị ka thyroid na-adịghị arụ ọrụ, gụnyere:

  • Ibu ibu
  • Ike ọgwụgwụ
  • Ntutu ntutu
  • Obere ndidi maka okpomọkụ oyi
  • Oge oge ịhụ nsọ
  • Afọ ntachi

Kedu ihe na-eme n'oge ule thyroxine?

Onye ọkachamara ahụike ga-ewere ihe nyocha ọbara site na akwara aka gị, jiri obere agịga. Mgbe etinyere agịga ahụ, a ga-achịkọta obere ọbara n'ime ule nyocha ma ọ bụ vial. Nwere ike na-eche ntakịrị ihe mgbe agịga na-abanye ma ọ bụ na-apụta. Nke a na-ewe ihe na-erughị nkeji ise.


Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?

Don’tkwesighi nkwadebe ọ bụla pụrụ iche maka nyocha ọbara thyroxine. Ọ bụrụ na onye na-ahụ maka ahụike gị enyela iwu nyocha ọzọ na ọbara gị, ị nwere ike ibu ọnụ (agaghị eri ma ọ bụ drinkụọ mmiri) ruo ọtụtụ awa tupu ule ahụ. Onye na-ahụ maka ahụike gị g’eme ka ị mara ma enwere ntuziaka puru iche iji soro.

Onwere ihe egwu di n’ule a?

O nwechaghị ihe egwu dị n’inyocha ọbara. May nwere ike ịnwe obere ihe mgbu ma ọ bụ mmerụ ahụ ebe etinyere agịga ahụ, mana ọtụtụ mgbaàmà na-apụ ngwa ngwa.

Kedu ihe nsonaazụ ahụ pụtara?

Nsonaazụ gị nwere ike ịdị n'ụdị T4, T4 n'efu, ma ọ bụ ndepụta T4 n'efu.

  • Nkọwa T4 n'efu na-agụnye usoro nke na-atụle T4 n'efu ma kee ya.
  • Uzo dị elu nke nyocha ọ bụla (ngụkọta T4, T4 n'efu, ma ọ bụ ntinye T4 n'efu) nwere ike igosi oke ọrụ thyroid, nke a makwaara dị ka hyperthyroidism.
  • Usoro dị ala nke nke ọ bụla n'ime ule a (ngụkọta T4, T4 n'efu, ma ọ bụ ntinye T4 n'efu) nwere ike igosi thyroid na-adịghị arụ ọrụ, nke a makwaara dị ka hypothyroidism.

Ọ bụrụ na nsonaazụ T4 gị adịghị njọ, onye na-ahụ maka ahụike gị nwere ike ịnyekwu nyocha thyroid iji nyere aka mee nchoputa. Ndị a nwere ike ịgụnye:


  • T3 thyroid hormone ule. T3 bụ hormone ọzọ nke thyroid mere.
  • Nyocha TSH (thyroid na-akpali akpali hormone) ule. TSH bụ homonụ nke pituitary gland mere. Ọ na - akpali thyroid iji mepụta homonụ T4 na T3.
  • Ule iji chọpụta ọrịa Graves, ọrịa autoimmune nke na-akpata hyperthyroidism
  • Ule iji chọpụta thyroiditis Hashimoto, ọrịa autoimmune nke na-akpata hypothyroidism

Mụtakwuo maka ule nyocha ụlọ, akara ngosi, na nghọta nsonaazụ.

Enwere ihe ọ bụla ọzọ m kwesịrị ịma gbasara nnwale thyroxine?

Mgbanwe nke thyroid nwere ike ime n'oge ime ime. Ọ bụ ezie na ọ bụghị ihe a na-ahụkarị, ụfọdụ ụmụ nwanyị nwere ike ibute ọrịa thyroid n'oge ime ime. Hyperthyroidism na-eme n'ihe dịka 0.1% na 0.4% nke afọ ime, ebe hypothyroidism na-eme n'ihe dịka 2.5% nke afọ ime.

Hyperthyroidism, na obere oge, hypothyroidism, nwere ike ịnọgide mgbe afọ ime. Ọ bụrụ na ị mepee ọnọdụ thyroid n'oge ime ime, onye nlekọta ahụike gị ga-enyocha ọnọdụ gị mgbe amuchara nwa gị. Ozokwa, ọ bụrụ na ị nwere akụkọ ihe mere eme nke ọrịa thyroid, jide n'aka na gị na onye nlekọta ahụike gị na-ekwurịta okwu ma ọ bụrụ na ị dị ime ma ọ bụ na-eche ị tụrụ ime.

Ntughari

  1. American Thyroid Association [Internet]. Church Falls (VA): American Thyroid Association; c2017. Ọnwụnwa na-arụ Ọrụ Thyroid [nke e kwuru na 2017 May 22]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://www.thyroid.org/thyroid-function-tests
  2. Hinkle J, Cheever K. Brunner & Suddarth's Akwụkwọ ntuziaka nke Laboratory na Diagnostic Tests. 2nd Ed, Ọdịdị. Philadelphia: Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Thryoxine, ọbara 485 p.
  3. Nnwale ụlọ nyocha na ntanetị [Intanet]. Washington DC: American Association maka Clinical Chemistry; C2001–2017. Free T4: Ule ahụ [emelitere 2014 Ọkt 16; zoro aka na 2017 Mee 22]; [ihe dị ka ihuenyo 4]. E Nweta site na: https://labtestsonline.org/understanding/analytes/t4/tab/test
  4. Nnwale ụlọ nyocha na ntanetị [Intanet]. Washington DC: American Association maka Clinical Chemistry; C2001–2017. Free T4: Ule Nlereanya [emelitere 2014 Oct 16; zoro aka na 2017 Mee 22]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://labtestsonline.org/understanding/analytes/t4/tab/sample
  5. Nnwale ụlọ nyocha na ntanetị [Intanet]. Washington DC: American Association maka Clinical Chemistry; C2001–2017. TSH: Nlereanya Ule [emelitere 2014 Ọkt 15; zoro aka na 2017 Mee 22]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://labtestsonline.org/understanding/analytes/tsh/tab/sample
  6. Merck Manual Consumer Version [Intanet]. Kenilworth (NJ): Merck & Co. Inc.; c2017. Nchịkọta nke Thyroid Gland [nke a kpọtụrụ 2017 May 22]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/thyroid-gland-disorders/overview-of-the-thyroid-gland
  7. Institutelọ Ọrụ Na-ahụ Maka Ọrịa Shuga na Ọrịa Digis na Akụrụ [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Ọrịa ili; 2012 Aug [kwupụtara na 2017 Mee 22]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://www.niddk.nih.gov/health-information/endocrine-diseases/graves-disease
  8. Institutelọ Ọrụ Na-ahụ Maka Ọrịa Shuga na Ọrịa Digis na Akụrụ [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Ọrịa Hashimoto; 2014 Mee [zoro aka na 2017 Mee 22]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://www.niddk.nih.gov/health-information/endocrine-diseases/hashimotos-disease
  9. Institutelọ Ọrụ Na-ahụ Maka Ọrịa Shuga na Ọrịa Digis na Akụrụ [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Nnwale nke thyroid; 2014 Mee [zoro aka na 2017 Mee 22]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://www.niddk.nih.gov/health-information/diagnostic-tests/thyroid
  10. National Heart, Lung, na Ọbara Institute [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Kedu ihe ize ndụ nke nyocha ọbara? [emelitere 2012 Jan 6; zoro aka na 2017 Mee 22]; [ihe dị ka ihuenyo 5]. Odi site na: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
  11. National Heart, Lung, na Ọbara Institute [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Ihe To Ga-atụ Anya Ule Ọbara [emelitere 2012 Jan 6; zoro aka na 2017 Mee 22]; [ihe dị ka ihuenyo 4]. E Nweta site na: https://www.nhlbi.nih.gov/health-topics/blood-tests
  12. Soldin OP. Nlekọta Ọrụ Thyroid na Ime Ime na Ọrịa Thyroid: Oge Ntugharị Na-akpata Trimester. Ọgwụ Ọgwụ Na-ahụ Maka Ọgwụ. [Intanet]. 2006 Feb [kpọtụrụ 2019 Jun 3]; 28 (1): 8-11. O nwere site na: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625634
  13. Mahadum nke Rochester Medical Center [Internet]. Rochester (NY): Mahadum nke Rochester Medical Center; c2017. Health Encyclopedia: Free na Bound T4 [nke a kpọtụrụ aha na 2017 May 22]; [ihe dị ka ihuenyo 2]. Nweta ya site na: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=t4_free_and_bound_blood
  14. Mahadum nke Rochester Medical Center [Internet]. Rochester (NY): Mahadum nke Rochester Medical Center; c2017. Encyclopedia Health: Free T4 [akpọrọ 2017 May 22]; [ihe dị ka ihuenyo 2]. O nwere site na: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=free_t4_thyroxine

Ejila ozi dị na saịtị a dị ka onye dochie anya nlekọta ahụike ọkachamara ma ọ bụ ndụmọdụ. Kpọtụrụ onye na-ahụ maka ahụike ma ọ bụrụ na ị nwere ajụjụ gbasara ahụike gị.

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