Cholinesterase test: ihe ọ bụ, ihe ọ bụ maka na ihe nsonaazụ pụtara

Ndinaya

• Gịnị ka ọ bụ maka
• Ihe njirimara
• Ihe nsonazụ ahụ pụtara

Nnwale cholinesterase bụ ule ụlọ nyocha achọrọ iji nyochaa ogo nke ikpughe onye ahụ na ngwaahịa ndị na-egbu egbu, dị ka ọgwụ ahụhụ, ụmụ ahụhụ, ahịhịa ọgwụ ma ọ bụ nri, dịka ọmụmaatụ, ya mere, ọ dabara adaba maka ndị ọrụ ugbo, ebe ha na-akpakọrịta mgbe niile ngwaahịa ugbo.

Cholinesterase bụ enzyme dị n'ahụ nke na-ahụ maka mmebi nke ihe a na-akpọ acetylcholine, onye na-ahụ maka ntanetị na-achịkwa ịchịkwa akwara na akwara. E nwere klas abụọ nke cholinesterase:

• - Erythrocyte cholinesterase, nke ọbara uhie uhie na-ebu;
• Plasma cholinesterase ma ọ bụ ọbara, nke bụ cholinesterase mepụtara site na imeju, pancreas na obere eriri afọ na nke na-ekesa na plasma ọbara.

Nlekota nke cholinesterase etoju di nkpa ka enwere ike ichota ma gbanwee ya ngbanwe obula, na-ezere nsogbu nke mmadu.

Gịnị ka ọ bụ maka

Dọkịta cholinesterase na-atụ aro ka ọ bụrụ iji nyochaa ogo nke ikpughe nke ndị ọrụ ugbo, dịka ọmụmaatụ, na ụmụ ahụhụ na ọgwụ ahụhụ.

Na mgbakwunye, enwere ike ịrịọ usoro ọgwụgwọ nke enzyme a iji nyochaa ndị ọrịa nwere ọrịa imeju, ọkachasị ndị megharịrị imeju umeji, ebe ọ bụ na ha na-agbadatakarị ọkwa cholinesterase.

Enwere ike igosi usoro ọgwụgwọ cholinesterase maka ndị nwere mmụba na-egbochi ịrụ ọrụ ziri ezi ma ọ bụ mmepụta nke enzyme a.

Ihe njirimara

Lineskpụrụ nyocha nke Cholinesterase na-agbanwe dị ka ụlọ nyocha na ngwa eji eme ule ahụ. Yabụ, ụkpụrụ nrụtụ aka dị n'etiti:

• Mụ nwoke: 4620 - 11500 U / L.
• Mụ nwanyị: 3930 - 10800 U / L

A na-eme nnwale a dị ka nyocha ọbara ọ bụla, ya bụ, a na-achịkọta obere ọbara ma ziga ya na laabu ka ha tụlee ngalaba biochemistry. Dabere na ụlọ nyocha ọ nwere ike ịkwado ka ịbuo ọnụ ma ọ dịkarịa ala awa 4.

Ihe nsonazụ ahụ pụtara

Gị ọkwa dị ala nke cholinesterase na-egosi ogologo oge na-egbu egbu na ọgwụ ahụhụ, nke bụ ihe dị ugbu a na ụmụ ahụhụ, pesticides na herbicides nwere ike igbochi ọrụ nke enzyme a, na-eduga na nchịkọta nke acetylcholine na nke nwere ike ibute ọdịdị nke ụfọdụ ihe ịrịba ama na mgbaàmà, dịka :

• Mbelata;
• Afọ ọsịsa;
• Akpịrị;
• Oke salivation;
• Nsogbu anya;
• Mbelata ọbara mgbali;
• Ike adịghị ike;
• Mkpọnwụ.

Ọ bụ ezie na mbelata nke ọkwa cholinesterase kachasị metụtara ị intoụbiga mmanya ókè, enwere ike ịbelata na enzyme a n'ihe banyere ịba ọcha n'anya, ọrịa imeju, nkụda mmụọ obi, nnukwu ọrịa na infarction.

Ya mere, ọ dị mkpa na nsonaazụ nke cholinesterase na-atụgharị ọnụ yana nsonaazụ nke nyocha ndị ọzọ ka e wee mata ihe kpatara mbelata na enzyme a wee nwee ike igosipụta ọgwụgwọ kachasị mma.

N'akụkụ aka nke ọzọ, ọkwa dị elu nke cholinesterase, na-emekarị n'ihi oke ibu, ọrịa shuga, ọrịa nephrotic na hyperthyroidism.