Nke a bụ nkwekọrịta na inye onyinye Convalescent Plasma maka ndị ọrịa COVID-19

Ndinaya

• Yabụ, Gịnị bụ ọgwụgwọ Plasma Convalescent, Kpọmkwem?
• Kedu onye nwere ike ịnye Plasma Convalescent maka COVID-19?
• Kedu ihe onyinye Convalescent Plasma na-enye?
• Nyochaa maka

Kemgbe ngwụsị March, ọrịa coronavirus na -aga n'ihu na -akụziri mba ahụ - na ụwa - ọtụtụ okwu ọhụrụ: ndọpụ mmekọrịta mmadụ na ibe ya, akụrụngwa nchedo onwe onye (PPE), ịkpọtụrụ kọntaktị, naanị ịkpọ aha ole na ole. Ọ dị ka a ga-asị na ụbọchị ọ bụla nke ọrịa na-efe efe (nke yiri ka ọ na-adịgide adịgide) enwere mmepe ọhụrụ nke na-ewepụta ezigbo ahịrịokwu iji gbakwunye na ọkọwa okwu COVID-19 na-eto eto. Otu n'ime mgbakwunye na nso nso a na okwu gị na -abawanye ụba? Usoro ọgwụgwọ plasma convalescent.

Amabeghị ya? M ga -akọwa…

Na Ọgọst 23, 2020 nchịkwa nri na ọgwụ US (FDA) nyere ikike iji ihe mberede nke plasma convalescent - akụkụ ọbara bara ụba nke a na-enweta n'aka ndị ọrịa COVID-19 gbakere - maka ọgwụgwọ ọrịa coronavirus siri ike. Mgbe ahụ, obere ihe karịrị otu izu ka e mesịrị, na Septemba 1, Kọmitii Ntuziaka Ọgwụ COVID-19, akụkụ nke National Institutes of Health (NIH), sonyeere mkparịta ụka ahụ, na-ekwu na enwere "data ezughị ezu iji kwado ma ọ bụ megidere iji ya. nke plasma convalescent maka ọgwụgwọ COVID-19. ”

Tupu ihe nkiri a, enyere ndị ọrịa COVID-19 na-arịa ọrịa plasma convalescent site na Mmemme Nweta Mgbasawanye nke Mayo Clinic (EAP), nke chọrọ ndebanye aha dọkịta iji rịọ plasma maka ndị ọrịa, dịka FDA si kwuo. Ugbu a, na -aga n'ihu, EAP akwụsịla ma nyefee ikike ikike ihe mberede nke FDA (EUA), nke na -enye ndị dọkịta na ụlọ ọgwụ ohere ịrịọ plasma na -ezuteghị ụfọdụ ntinye aha. Mana, dị ka nkwupụta NIH kwusiri ike na nso nso a, achọrọ nyocha karịa tupu onye ọ bụla nwee ike ịkwado usoro ọgwụgwọ plasma convalescent dị ka ọgwụgwọ ntụkwasị obi nke COVID-19.

A na-enweta ọgwụgwọ plasma convalescent karịa mgbe ọ bụla dị ka ọgwụgwọ enwere ike maka COVID-19 na US, mana kedu ihe ọ bụ? Kedu otu ị ga-esi nye plasma convalescent maka ndị ọrịa COVID-19? N'ihu, ihe niile ịchọrọ ịma.

Yabụ, Gịnị bụ ọgwụgwọ Plasma Convalescent, Kpọmkwem?

Nke mbụ, gịnị bụ plasma convalescent? Convalescent (adjective na noun) na -ezo aka na onye ọ bụla na -agbake n'ọrịa, na plasma bụ odo, mmiri mmiri nke nwere ọgwụ mgbochi maka ọrịa, dị ka FDA si kwuo. Ma, ọ bụrụ na ị hapụ klaasị bayoloji klaasị nke asaa, ọgwụ mgbochi ọrịa bụ protein ndị etinyere iji lụso ọrịa ụfọdụ ọgụ mgbe ị nwetasịrị ọrịa ahụ.

Yabụ, plasma convalescent bụ naanị plasma sitere n'aka onye gbakere n'ọrịa - na nke a, COVID-19, Brenda Grossman, MD, onye isi ụlọ ọgwụ transfusion Medicine na Barnes-Jewish Hospital, na prọfesọ na Mahadum Mahadum Washington kwuru. Ọgwụ na St. Louis. "Ejiwo plasma convalescent n'oge gara aga, nwere ogo dị iche iche nke ịdị irè, maka ọtụtụ ọrịa na-efe efe, gụnyere Spanish flu, SARS, MERS, na Ebola," ka Dr. Grossman na-ekwu.

Ugbu a, ebe a ka '' ọgwụgwọ '' na -abata: Ozugbo enwetara plasma site n'aka onye gbakere, a na -enyefe ya onye ọrịa ugbu a (yana nke na -adịkarị ike) ka ọgwụ mgbochi ọrịa wee nwee olile anya 'wepụ nje ahụ ma nwee ike ịkwalite mkpochapụ nke nje ahụ. site n'ahụ, ”Emily Stoneman, MD, ọkachamara ọrịa na -efe efe na Mahadum Michigan na Ann Arbor na -ekwu. N'ikwu ya n'ụzọ ọzọ, a na-eji ya "ịkwalite ihe mgbochi nke onye ọrịa ma nwee olileanya ibelata mmetụta ọrịa ahụ."

Mana, dị ka ọ dị na ndụ (ugh, mkpakọrịta nwoke na nwaanyị), oge bụ ihe niile. Dr. Stoneman na-akọwa, "Ọ na-ewe ihe dị ka izu abụọ maka ndị nwere COVID-19 imepụta ọgwụ mgbochi ndị a n'onwe ha," Ọ bụrụ na enyere plasma convalescent n'oge ọrịa, ọ nwere ike belata oge ọrịa ma gbochie. Ya mere, ọ bụ ezie na a ka chọkwuru nyocha iji chọpụta ịdị mma nke ọgwụgwọ plasma convalescent, ebumnuche dị ugbu a bụ na tupu onye ọrịa anata ọgwụgwọ ahụ, o yikarịrị ka ha ga -ahụ nsonaazụ dị mma. (metụtara: Otu esi emeri nchegbu ahụike n'oge COVID-19, na gafere)

Kedu onye nwere ike ịnye Plasma Convalescent maka COVID-19?

Ntozu nọmba nke mbụ: ị nwere coronavirus ma ị nwere ule iji gosi ya.

"Ndị mmadụ nwere ike inye onyinye plasma ma ọ bụrụ na ha nwere ọrịa COVID-19 nwere akwụkwọ nyocha ụlọ nyocha (ma ọ bụ nasopharyngeal [nasal] swab ma ọ bụ nyocha nke ọma), agbakeela nke ọma ma bụrụ asymptomatic ọbụlagodi izu abụọ," ka Hyunah Yoon, MD kwuru. Ọkachamara ọrịa na Albert Einstein College of Medicine. (Gụọ kwa: Kedu ihe ezigbo nnwale mgbochi ahụ pụtara?)

Ịchọpụtabeghị nkwenye mana obi siri gị ike na ị nwere mgbaàmà coronavirus? Ozi ọma: Ị nwere ike ịhazi oge nnwale mgbochi mmadụ na mpaghara Red Cross nke America, ma ọ bụrụ na nsonaazụ ya dị mma maka ọgwụ mgbochi ọrịa, gaa n'ihu otu a - ya bụ, n'ezie, ọ bụrụhaala na ị mezuru ihe ndị ọzọ chọrọ inye onyinye, dị ka enweghị akara. maka opekata mpe ụbọchị 14 tupu inye onyinye. Ọ bụ ezie na FDA na-atụ aro izu abụọ na-enweghị ihe mgbaàmà, ụfọdụ ụlọ ọgwụ na otu nwere ike ịchọ ka ndị na-enye onyinye ghara inwe mgbaàmà maka ụbọchị 28, Dr. Grossman kwuru

E wezụga nke ahụ, American Red Cross na -achọkwa ka ndị na -enye plasma convalescent dịkarịa ala afọ 17, tụọ 110 lbs, ma mezuo ihe onyinye ọbara nke nzukọ a chọrọ. (Lelee ntuziaka a maka inye ọbara iji hụ ma ị dị mma ịga dabere na ihe ndị a chọrọ.) Ọ dị mkpa iburu n'uche na n'oge ọrịa na-anaghị efe efe, ị nwere ike (yana, TBH) kwesịkwara inye onyinye plasma ka ejiri ya mee ihe. ọgwụgwọ ndị ọzọ maka, sịnụ, ndị ọrịa kansa na ọkụ na ihe mberede metụtara, dị ka ụlọ ọrụ ọbara New York si kwuo.

Kedu ihe onyinye Convalescent Plasma na-enye?

Ozugbo ị haziri nleta na etiti onyinye mpaghara gị, ọ bụ oge ịkwadebe. Otú ọ dị, naanị ihe ọ pụtara bụ ị drinkingụ mmiri zuru oke (opekata mpe 16oz.) Na iri nri nwere protein na iron (anụ uhie, azụ, agwa, akwụkwọ nri) awa ndị na-ebute nhọpụta gị iji gbochie akpịrị ịkpọ nkụ, isi ọwụwa, na dizziness, dị ka American Red Cross si kwuo.

Ọ maara nke ọma? Nke ahụ bụ n'ihi na inye onyinye plasma na ọbara yiri ya - belụsọ maka inye onyinye. Ọ bụrụ na ị nyela ọbara, ị mara na mmiri ahụ na -esi n'aka gị banye n'ime akpa wee nke ọzọ bụ akụkọ ihe mere eme. Inye onyinye plasma dịtụ ntakịrị, hiere ụzọ, dị mgbagwoju anya. N'oge onyinye naanị plasma, a na-amịpụta ọbara site n'otu ogwe aka wee zipu ya site na igwe ọgbara ọhụrụ nke na-anakọta plasma wee weghachi mkpụrụ ndụ ọbara uhie na platelet-yana nnu nnu (aka mmiri nnu)-laghachiri n'ime ahụ gị. Nke a dị mkpa dị ka plasma bụ 92 pasent mmiri, dị ka American Red Cross si kwuo, na usoro inye onyinye na-abawanye ohere gị maka akpịrị ịkpọ nkụ (karịa na nke a n'okpuru). Usoro onyinye niile kwesịrị iwe naanị ihe dị ka otu awa na nkeji iri na ise (naanị ihe dị ka nkeji iri na ise karịa onyinye naanị ọbara), dị ka American Red Cross si kwuo.

Dịkwa ka onyinye ọbara, mmetụta ndị dị n'inye plasma dị ntakịrị - ka emechara, ị ga -enwerịrị ezigbo ahụike iji ruo eru na mbụ. N'ikwu ya, dị ka m kwuru n'elu, akpịrị ịkpọ nkụ bụ ihe nwere ike ime. Maka nke ahụ, ọ dị mkpa na ị ga -agbatịkwu nri mmiri gị n'ụbọchị na -esote ma zere ibuli elu na mmega ahụ maka opekata mpe ụbọchị. Echegbula onwe gị maka ahụ gị na -agbada ụfọdụ mmiri dị mkpa, ebe ọ nwere ike (ma mee) dochie olu ọbara ma ọ bụ plasma n'ime awa 48.

Maka ihe egwu COVID-19 gị? Nke ahụ ekwesịghị ịbụ nchegbu ebe a. A na-eme ọtụtụ ebe a na-enye onyinye ọbara site na oge ọhụhụ naanị iji nwaa ịkwado omume ndọpụ uche ọha kacha mma ma tinyekwa nlezianya anya ọzọ dịka erslọ Ọrụ Maka Nchịkwa na Mgbochi Ọrịa (CDC).

Ozi dị na akụkọ a ziri ezi ka ọ dị n'oge akụkọ. Ka mmelite banyere coronavirus COVID-19 na-aga n'ihu, ọ ga-ekwe omume na ụfọdụ ozi na ndụmọdụ dị na akụkọ a agbanweela kemgbe mbipụta mbụ. Anyị na-agba gị ume ka ị jiri akụrụngwa dịka CDC, WHO na ngalaba ahụike ọha mpaghara gị wee na-enyocha mgbe niile yana ndụmọdụ na ndụmọdụ kacha ọhụrụ.

Nyochaa maka