Nnwale Ule CCP

Ndinaya

• Kedu ihe nyocha CCP?
• Kedu ihe eji ya?
• Kedu ihe kpatara m ji chọọ nnwale mgbochi CCP?
• Kedu ihe na-eme n'oge ule mgbochi CCP?
• Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?
• Onwere ihe egwu di n’ule a?
• Kedu ihe nsonaazụ ahụ pụtara?
• Onwere ihe ozo ichoro ima banyere CCP antibody test?
• Ntughari

Kedu ihe nyocha CCP?

Nnwale a na-achọ ọgwụ nje CCP (cyclic citrullinated peptide) na-alụso ọrịa ọgụ n’ime ọbara. Ihe mgbochi CCP, nke a na-akpọkwa anti-CCP, bụ ụdị mgbochi a na-akpọ autoantibodies. Antibodies na autoantibodies bụ protein nke usoro ahụ ji alụso ọrịa ọgụ na-arụ. Ihe mgbochi na-echebe gị pụọ na ọrịa site na ịlụ ọgụ megide ndị si mba ọzọ dị ka nje na nje. Autoantibodies nwere ike ibute ọrịa site na ịwakpo sel ndị dị mma n'ahụ site na ndudue.

Ihe mgbochi CCP lekwasịrị ahụ ike anya na nkwonkwo. Ọ bụrụ na ahụta nje CCP n’ọbara gị, ọ nwere ike ịbụ ihe mgbaàmà nke ogbu na nkwonkwo na-arịa ogbu na nkwonkwo. Ọrịa ogbu ogbu na nkwonkwo bụ ọrịa na-aga n'ihu, ọrịa autoimmune nke na-akpata mgbu, ọzịza, na isi ike na nkwonkwo. A na-ahụ nje nje CCP n'ihe karịrị pasent 75 nke ndị nwere ọrịa ogbu na nkwonkwo. Ọ fọrọ nke nta ka ọ bụrụ na ahụghị ha na ndị na-enweghị ọrịa ahụ.

Aha ndị ọzọ:

Kedu ihe eji ya?

A na-eji ule mgbochi CCP enyere aka chọpụta ọrịa ogbu na nkwonkwo. A na-emekarị ya ma ọ bụ mgbe ọ na-anwale ule rheumatoid (RF). Rheumatoid bụ ụdị ọzọ nke autoantibody. Nyocha RF bụbu ihe nyocha kachasị iji nyere aka chọpụta ọrịa ogbu na nkwonkwo. Mana enwere ike ịchọta ihe RF na ndị nwere ọrịa autoimmune ndị ọzọ yana ọbụlagodi ụfọdụ ndị ahụike. Ọtụtụ nnyocha egosiwo na nje CCP na-enye nchoputa ziri ezi nke ọrịa ogbu na nkwonkwo ma e jiri ya tụnyere ule RF.

Kedu ihe kpatara m ji chọọ nnwale mgbochi CCP?

May nwere ike ịchọ ule a ma ọ bụrụ na ị nwere mgbaàmà nke ọrịa ogbu na nkwonkwo. Ndị a gụnyere:

• Nkwonkwo mgbu
• Nkwesi ike nkwonkwo, ọkachasị n'ụtụtụ
• Ọzịza nkwonkwo
• Ike ọgwụgwụ
• Ahụ ọkụ dị ala

Nwekwara ike ịchọ ule a ma ọ bụrụ na ule ndị ọzọ enweghị ike ikwenye ma ọ bụ wepụ ihe nyocha nke ọrịa ogbu na nkwonkwo.

Kedu ihe na-eme n'oge ule mgbochi CCP?

Onye ọkachamara ahụike ga-ewere ihe nyocha ọbara site na akwara aka gị, jiri obere agịga. Mgbe etinyere agịga ahụ, a ga-achịkọta obere ọbara n'ime ule nyocha ma ọ bụ vial. Nwere ike na-eche ntakịrị ihe mgbe agịga na-abanye ma ọ bụ na-apụta. Nke a na-ewe ihe na-erughị nkeji ise.

Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?

Jide n'aka na ị gwa onye nlekọta ahụike gị banyere ọgwụ niile, vitamin, na ihe mgbakwunye nri ị na-ewere. Nwere ike ịkwụsị ị substancesụ ụfọdụ ọgwụ maka awa 8 tupu ule gị.

Onwere ihe egwu di n’ule a?

O nwechaghị ihe egwu dị n’inyocha ọbara. May nwere ike ịnwe obere ihe mgbu ma ọ bụ mmerụ ahụ ebe etinyere agịga ahụ, mana ọtụtụ mgbaàmà na-apụ ngwa ngwa.

Kedu ihe nsonaazụ ahụ pụtara?

Ọ bụrụ na nsonaazụ antip CCP gị dị mma, ọ pụtara na a hụrụ nje ndị a n'ọbara gị. Nsonaazụ na-ezighi ezi apụtaghị na ahụrụ nje CCP. Ihe nsonaazụ ndị a nwere ike ịdabere na nsonaazụ nyocha rheumatoid (RF) yana ule anụ ahụ.

Ọ bụrụ na ị nwere mgbaàmà nke ọrịa ogbu na nkwonkwo, nsonaazụ gị na-egosikwa:

• Ngwurugwu CCP dị mma na RF dị mma, ọ nwere ike ịpụta na ị nwere ọrịa ogbu na nkwonkwo.
• Ngwurugwu CCP dị mma na RF na-adịghị mma, ọ nwere ike ịpụta na ị nọ na mmalite mmalite nke ọrịa ogbu na nkwonkwo ma ọ bụ na ị ga-azụlite ya n'ọdịnihu.
• Ihe mgbochi CCP na-adịghị mma na RF na-adịghị mma, ọ pụtara na ị ga-enwekarị ọrịa ogbu na nkwonkwo. Onye na-eweta ọrụ gị nwere ike ịchọ nyocha ọzọ iji nyere aka chọpụta ihe kpatara ọrịa gị.

Mụtakwuo maka ule nyocha ụlọ, akara ngosi, na nghọta nsonaazụ.

Onwere ihe ozo ichoro ima banyere CCP antibody test?

Ọrịa ogbu na nkwonkwo nwere ike isi ike ịchọpụta, ọkachasị n’oge ọ malitere. Onye na-enye gị nwere ike ịtụ otu nyocha ma ọ bụ karịa na mgbakwunye CCP antibody na ule RF. Ndị a gụnyere ụzarị ọkụ nke nkwonkwo gị na ule ọbara ndị a:

• Erythrocyte sedimentation ọnụego (ESR)
• Nnyocha mmiri nke Synovial
• C-na-arụ ọrụ protein
• Antinuclear antibody

Nnwale ọbara ndị a nwere ike igosi ihe ịrịba ama nke mbufụt. Mbufụt bụ ụdị usoro nzaghachi nke usoro ahụ ji alụso ọrịa ọgụ. O nwere ike ịbụ ihe mgbaàmà nke ọrịa ogbu na nkwonkwo.

Ntughari

1. Abdul Wahab A, Mohammad M, Rahman MM, Mohamed Kwuru MS. Anti-cyclic citrullinated peptide antibody bụ ezigbo akara ngosi maka nyocha nke ọrịa ogbu na nkwonkwo. Pak J Ahụike Sci. 2013 May-Jun [akpọrọ 2020 Feb 12]; 29 (3): 773-77. O nwere site na: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809312
2. American College of Rheumatology [Internet]. Atlanta: American College nke Rheumatology; Agugu 2020. Okwunkowa: Nnwale mgbochi antipide (CCP) nke Cyclic citrullinated (CCP); [akpọrọ 2020 Feb 12]; [ihe dị ka ihuenyo 3]. O nwere site na: https://www.rheumatology.org/Learning-Center/Glossary/ArticleType/ArticleView/ArticleID/439
3. Ogbu na nkwonkwo [Internet]. Atlanta: Ogbu na nkwonkwo; Arthritis Rheumatoid; [akpọrọ 2020 Feb 12]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://www.arthritis.org/diseases/rheumatoid-arthritis
4. Velọ Ọgwụ Cleveland [Internet]. Cleveland (OH): velọ Ọgwụ Cleveland; Agugu 2020. Arthritis Rheumatoid: Nchoputa na Ule; [akpọrọ 2020 Feb 12]; [ihe dị ka ihuenyo 4]. E si na: https://my.clevelandclinic.org/health/diseases/4924-rheumatoid-arthritis/diagnosis-and-tests
5. Familydoctor.org [Intanet]. Leawood (KS): American Academy of Family Dọkịta; Agugu 2020. Arthritis Rheumatoid; [emelitere 2018 Aug 28; zoro aka na 2020 Feb 12]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://familydoctor.org/condition/rheumatoid-arthritis
6. HSS [Intanet]. New York: Hospitallọ Ọgwụ maka Surwa Ahụ Pụrụ Iche; c2019. Ghọta helọ nyocha Ọrịa ogbu na nkwonkwo nke Rheumatoid; [emelitere 2018 Mar 26; zoro aka na 2020 Feb 12]; [ihe dị ka ihuenyo 4]. E Nweta site na: https://www.hss.edu/condition_understanding-rheumatoid-arthritis-lab-tests-results.asp
7. Nnwale ụlọ nyocha na ntanetị [Intanet]. Washington DC: American Association maka Clinical Chemistry; C2001–2020. Nchekwa onwe; [emelitere 2019 Nov 13; zoro aka na 2020 Feb 12]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://labtestsonline.org/tests/autoantibodies
8. Nnwale ụlọ nyocha na ntanetị [Intanet]. Washington DC: American Association maka Clinical Chemistry; C2001–2020. Cyclic Citrullinated Peptide Antibody; [emelitere 2019 Dec 24; zoro aka na 2020 Feb 12]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://labtestsonline.org/tests/cyclic-citrullinated-peptide-antibody
9. Nnwale ụlọ nyocha na ntanetị [Intanet]. Washington DC: American Association maka Clinical Chemistry; C2001–2020. Mbufụt; [emelitere 2017 Jul 10; zoro aka na 2020 Feb 12]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://labtestsonline.org/glossary/inflammation
10. Nnwale ụlọ nyocha na ntanetị [Intanet]. Washington DC: American Association maka Clinical Chemistry; C2001–2020. Ihe Rheumatoid (RF); [emelitere 2020 Jan 13; zoro aka na 2020 Feb 12]; [ihe dị ka ihuenyo 2]. Odi na: https://labtestsonline.org/tests/rheumatoid-factor-rf
11. Yolọ Ọgwụ Mayo [Internet]. Ntọala Mayo maka Mmụta Ahụike na Nnyocha; C1998–2020. Rheumatoid ogbu na nkwonkwo: Nchoputa na ọgwụgwọ; 2019 Mar 1 [akpọrọ 2020 Feb 12]; [ihe dị ka ihuenyo 4]. E si na: https://www.mayoclinic.org/diseases-condition/rheumatoid-arthritis/diagnosis-treatment/drc-20353653
12. Mayo Clinic Laboratories [Intanet]. Ntọala Mayo maka Mmụta Ahụike na Nnyocha; C1995–2020. Ule CCP: Ihe Nlekọta Peptide Na-akpata Cyclic, IgG, ọbara: Clinical and Interpretive; [akpọrọ 2020 Feb 12]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/84182
13. Merck Manual Consumer Version [Intanet]. Kenilworth (NJ): Merck & Co. Inc.; Agugu 2020. Ọrịa ogbu ogbu na nkwonkwo (RA); 2019 Feb [akpọrọ 2020 Feb 12]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://www.merckmanuals.com/home/bone,-joint,-and-muscle-disorders/joint-disorders/rheumatoid-arthritis-ra
14. National Heart, Lung, na Ọbara Institute [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Nnwale ọbara; [akpọrọ 2020 Feb 12]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://www.nhlbi.nih.gov/health-topics/blood-tests
15. Ọrịa ogbu ogbu na nkwonkwo: Rheumatoid ogbu na nkwonkwo Nkwado Network [Internet]. Orlando (FL): Rheumatoid Arthritis Nkwado Network; RA na Anti-CCP: Gini bu Nzube nke Nnwale CCP?; 2018 Oct 27 [akpọrọ 2020 Feb 12]; [ihe dị ka ihuenyo 3]. O nwere site na: https://www.rheumatoidarthritis.org/ra/diagnosis/anti-ccp
16. Mahadum nke Rochester Medical Center [Internet]. Rochester (NY): Mahadum nke Rochester Medical Center; Agugu 2020. Ahụike Encyclopedia: CCP; [akpọrọ 2020 Feb 12]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=ccp

Ejila ozi dị na saịtị a dị ka onye dochie anya nlekọta ahụike ọkachamara ma ọ bụ ndụmọdụ. Kpọtụrụ onye na-ahụ maka ahụike ma ọ bụrụ na ị nwere ajụjụ gbasara ahụike gị.