Jụọ Dọkịta Nri: Eziokwu Banyere 5-HTP

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Ajụjụ: Ịnara 5-HTP ọ ga-enyere m aka ifelata?

A: Eleghị anya ọ bụghị, mana ọ dabere. 5-hydroxy-L-tryptophan bụ ihe sitere na amino acid tryptophan ma gbanwee ya na serotonin neurotransmitter na ụbụrụ. Kedu ihe jikọrọ nke ahụ na mbelata ibu? Serotonin bụ neurotransmitter nwere ọtụtụ akụkụ, otu n'ime ọrụ ya na-emetụta agụụ. (Ọ dịtụla mgbe ị nọ na coma nke na-akpata carbohydrate ebe agụụ gị kwụsịrị kpamkpam? Serotonin nwere aka na nke ahụ.)

N'ihi njikọ a na agụụ, ịmegharị ọkwa serotonin na mmetụta iji kpalite oke ibu ibu bụ nchụso ụlọ ọrụ ọgwụ. Otu n'ime ndị kasị ama (ma ọ bụ aha ọjọọ) ndenye ọgwụ arọ-ọnwụ ọgwụ, Phentermine, nwere a obi umeala mmetụta na serotonin ntọhapụ.

A bịa na nyocha n'ezie na 5-HTP yana mmetụta ya na oke ibu, ị gaghị ahụ ọtụtụ ihe. N'otu obere ọmụmụ, ndị nyocha Italiantali tinyere otu oke ibu, hyperphagic (sayensị maka "iri oke nri") ndị okenye na nri kalori 1,200 wee nye ọkara n'ime ha milligram 300 nke 5-HTP iji were nkeji iri atọ tupu nri ọ bụla. Mgbe izu iri na abụọ gasịrị, ndị sonyere na-efunahụ ihe dị ka kilogram 7.2 ma e jiri ya tụnyere 4 pound maka ndị ọzọ, bụ ndị, n'amaghị ama, were placebo.

Ihe dị mkpa iburu n'uche bụ na n'agbanyeghị oke ibu maka otu placebo adịghị ọnụ ọgụgụ, n'oge ọkara nke abụọ nke ọmụmụ ahụ, enyere ndị niile sonyere ntuziaka akọwapụtara iji belata oriri kalori ha. Otu shuga-pill agbagharala akara kalori ihe fọrọ nke nta ka ọ bụrụ narị calorie 800. Nye m, nke a dị ka ịghara ịgbaso ntuziaka karịa mmetụta mgbakwunye.

Ma ọ bụ ezie na ọ dị ka 5-HTP nwere ike inye aka na ọnwụ dị arọ, maka onye buru oke ibu ga-efunahụ kilogram 7 n'ime izu iri na abụọ ma na-eri nri nwere oke calorie abụghị ihe dị ịrịba ama.

N'èzí ọmụmụ a, ọnweghị ọtụtụ ihe-ewezuga hypotheses na usoro biochemical-iji gosi na 5-HTP bụ ihe na-egbochi agụụ. Ọ bụrụ na ị na-emega ahụ mgbe niile ma na-agbaso atụmatụ nri kalori na carbohydrate, mgbe ahụ ọ ga-esiri m ike ịhụ uru maka ịgbakwunye 5-HTP.

Ọ bụrụ na ị ka nwere mmasị na-ewere 5-HTP, mara na ọ na-ere ahịa ngwa ngwa dịka ọ dị ka enweghị nchekwa yana mmetụta enweghị mmetụta, mana onye ọ bụla na-ewere ọgwụ mgbochi, nke nwere ike inye aka n'ịba uru, kwesịrị izere iwere mgbakwunye ahụ, ebe ọ nwere ike ọgbaghara. mmetụta na ọgwụ chọrọ nke serotonin na antidepressants.

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