Usoro ọgwụgwọ Thrombolytic

Usoro ọgwụgwọ thrombolytic bụ iji ọgwụ ọjọọ eme ihe ma ọ bụ mebie mkpụkọ ọbara, nke bụ isi ihe kpatara obi ọgụ na ọrịa strok.

A na-anabata ọgwụ thrombolytic maka ọgwụgwọ mberede nke ọrịa strok na nkụchi obi. Ọgwụ a na-ejikarị eme ihe maka ọgwụgwọ thrombolytic bụ anụ ahụ plasminogen activator (tPA), mana ọgwụ ndị ọzọ nwere ike ime otu ihe ahụ.

Dị ka o kwesịrị, ị kwesịrị ịnara ọgwụ thrombolytic n'ime nkeji 30 mbụ mgbe ị rutere n'ụlọ ọgwụ maka ọgwụgwọ.

Mwakpo obi

Ihe mgbochi ọbara nwere ike igbochi akwara obi. Nke a nwere ike ibute nkụchi obi, mgbe akụkụ nke akwara obi nwụrụ n'ihi enweghị oxygen na-ebute ọbara.

Thrombolytics na-arụ ọrụ site na igbari nnukwu clot ngwa ngwa. Nke a na - enyere aka ịmalitegharia ọbara na - abanye n’obi wee nyere aka gbochie mmebi nke akwara obi. Thrombolytics nwere ike ịkwụsị nkụchi obi nke ga - abụ ibu ma ọ bụ nwee ike ịnwụ. Nsonaazụ dị mma ma ọ bụrụ na ịnweta ọgwụ thrombolytic n'ime awa iri na abụọ mgbe nkụchi obi malitere. Ma, ngwa ngwa ọgwụgwọ malitere, ihe ka mma na-arụpụta.

Ọgwụ ahụ na-eweghachite ụfọdụ ọbara na-abanye n'obi na ọtụtụ mmadụ. Otú ọ dị, ọbara ọbara nwere ike ọ gaghị abụcha ihe zuru oke ma enwere ike inwe obere akwara mebiri emebi. Enwere ike ịchọ ọgwụgwọ ọzọ, dị ka catheterization obi na angioplasty na nsị, nwere ike ịdị mkpa.

Onye na - ahụ maka ahụike gị ga - ekpebi mkpebi banyere ma ọ ga - enye gị ọgwụ thrombolytic maka nkụchi obi n'ọtụtụ ihe. Ihe ndị a gụnyere akụkọ ihe mere eme nke mgbu obi na nsonaazụ nke nnwale ECG.

Ihe ndị ọzọ ejiri mara ma ị bụ ezigbo nwa akwukwo maka thrombolytics gụnyere:

• Afọ (ndị agadi nọ n'ihe ize ndụ nke nsogbu)
• Mmekọahụ
• Akụkọ ahụike (gụnyere akụkọ gbasara ọrịa obi gara aga, ọrịa shuga, ọbara mgbali elu, ma ọ bụ ọnụọgụ obi)

Na mkpokọta, enweghi ike inye thrombolytics ma ọ bụrụ na inwere:

• Ọrịa na-emerụ ahụ n'isi nso
• Nsogbu ọbara ọgbụgba
• Ọrịa na-agba ọbara
• Ime afọ ime
• Surgerywa ahụ n'oge na-adịbeghị anya
• Were ọgwụ na-eme ka ọbara dị ka Coumadin
• Nsogbu
• Ọbara mgbali elu anaghị achịkwa (nke siri ike)

MKP .R.

Ọtụtụ ọrịa strok na-akpata mgbe mkpịsị ọbara na-abanye na arịa ọbara n'ime ụbụrụ ma gbochie ọbara na-asọba na mpaghara ahụ. Maka ụdị ọrịa strok dị otú ahụ (ọrịa mgbu), a pụrụ iji thrombolytics nyere aka igbari eriri ahụ ngwa ngwa. Inye thrombolytics n’ime awa 3 nke ihe mgbaàmà izizi mbụ nwere ike inye aka belata mmachi na nkwarụ.

Mkpebi inye ọgwụ ahụ dabere na:

• Brain CT nyocha iji jide n'aka na enweghi ọbara ọgbụgba
• Nnyocha ahụ nke na-egosi ọrịa strok dị mkpa
• Akụkọ banyere ahụike gị

Dị ka ọ dị na nkụchi obi, a naghị enyekarị ọgwụ na-agbaze clot ma ọ bụrụ na ị nwere otu nsogbu ahụike ndị ọzọ edepụtara n'elu.

A naghị enye onye na-arịa ọrịa strok nke metụtara ọbara ọgbụgba na ụbụrụ. Ha nwere ike ime ka ọrịa strok ahụ ka njọ site n'ime ka ọbara ọgbụgba na-arịwanye elu.

Ihe ize ndụ

Ọbara ọgbụgba bụ ihe egwu kachasị. O nwere ike ịbụ ihe na-eyi ndụ egwu.

Obere ọbara ọgbụgba site na goms ma ọ bụ imi nwere ike ime na ihe dịka 25% nke ndị na-enweta ọgwụ ahụ. Ọbara ọgbụgba n'ime ụbụrụ pụtara ihe dịka 1% nke oge. Ihe ize ndụ a bụ otu ihe maka ọrịa strok na nkụchi obi.

Ọ bụrụ na a na-eche thrombolytics dị oke egwu, ọgwụgwọ ndị ọzọ nwere ike ịme maka mkpụkọ na-akpata ọrịa strok ma ọ bụ nkụchi obi gụnyere:

• Mwepụ nke clot (thrombectomy)
• Usoro imeghe akwara ma ọ bụ mechie nke ikpuchi ọbara nke na-enye ọbara n’obi ma ọ bụ ụbụrụ

Kpọtụrụ onye na-elekọta ahụike ma ọ bụ kpọọ 911

Mgbu obi na ọrịa strok bụ ihe mberede ahụike. Ọgwụgwọ ngwa ngwa na thrombolytics na-amalite, ọ ka mma ohere maka nsonaazụ ọma.

Tissue plasminogen onye na-arụ ọrụ; TPA; Alteplase; Ntughari; Tenecteplase; Mee ọ rụọ ọrụ thrombolytic gị n'ụlọnga; Uwe na-agbaze ndị mmadụ; Usoro ọgwụgwọ; Ọkụ - thrombolytic; Mwakpo obi - thrombolytic; Nnukwu embolism - thrombolytic; Thrombosis - thrombolytic; Lanoteplase; Staphylokinase; Streptokinase (SK); Urokinase; Ọrịa strok - ọgwụgwọ thrombolytic; Mwakpo obi - ọgwụgwọ thrombolytic; Ọrịa - thrombolysis; Mwakpo obi - thrombolysis; Myocardial infarction - thrombolysis

• Ọkụ
• Thrombus
• Zipu mgbochi myocardial infarction ECG

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Agụụ TJ, Meurer WJ. Ọkụ. Na: Mgbidi RM, Hockberger RS, Gausche-Hill M, eds. Ngwọta Mberede nke Rosen: Echiche na usoro ọgwụgwọ. Agba nke 9. Philadelphia, PA: Elsevier; 2018: isi nke 91.

Jaffer IH, Weitz JI. Antithrombotic ọgwụ. Na: Hoffman R, Benz EJ, Silberstein LE, et al, ndị ọzọ. Hematology: ickpụrụ na Omume. Nke 7. Philadelphia, PA: Elsevier; 2018: isi 149.

O'Gara PT, Kushner FG, Ascheim DD, et al. Ntuziaka 2013 ACCF / AHA maka njikwa nke infarction myocardial ST-elu: akụkọ nke American College of Cardiology Foundation / American Heart Association Task Force on Practice Guidelines. Mgbaghari. 2013; 127 (4): 529-555. PMID: 23247303 pubmed.ncbi.nlm.nih.gov/23247303/.