Carcinoma adrenocortical

Adrenocortical carcinoma (ACC) bụ ọrịa cancer nke adrenal glands. Akụkụ ahụ adrenal bụ glands nke nwere triangle abụọ. Otu gland dị n’elu akụrụ nke ọ bụla.

ACC na-ahụkarị ụmụaka ndị na-erubeghị afọ 5 na ndị okenye nọ n’afọ 40 na 50.

Ọnọdụ a nwere ike jikọta ya na ọrịa cancer nke sitere na ezinụlọ (ketara). Menmụ nwoke na ụmụ nwanyị nwere ike ịzụlite akpụ a.

ACC nwere ike mepụta homonụ cortisol, aldosterone, estrogen, ma ọ bụ testosterone, yana homonụ ndị ọzọ. N’ụmụ nwanyị etuto ahụ na-ewepụtakarị homonụ ndị a, nke nwere ike ibute àgwà nwoke.

ACC dị ezigbo ụkọ. Ihe kpatara ya amaghị.

Mgbaàmà nke ụba cortisol ma ọ bụ hormones gland gland nwere ike ịgụnye:

• Abụba, mkpirisi hump elu na azụ dị n'okpuru olu (buffalo hump)
• Ihu, ihu gbara agba na pudgy cheeks (ọnwa ihu)
• Ibu
• Ntughari adighi ike (ogologo oge)
• Virilization - ọdịdị nke njirimara nwoke, gụnyere ntutu dị ukwuu (ọkachasị na ihu), ntutu isi, ihe otutu, olu dị omimi, yana nnukwu nwanyị (nwanyị)

Mgbaàmà nke ụba aldosterone bụ otu ihe mgbaàmà nke obere potassium, ma gụnye:

• Ọkpụkpụ akwara
• Adịghị ike
• Mgbu afọ

Onye nlekọta ahụike ga-eme nyocha anụ ahụ ma jụọ maka ihe mgbaàmà gị.

A ga-eme nyocha ọbara iji lelee ogo homonụ:

• ACTH larịị ga-ala.
• Aldosterone ga-adị elu.
• Cortisol larịị ga-adị elu.
• Potassium larịị ga-ala.
• Homonụ nwoke ma ọ bụ nwanyị nwere ike ịdị elu na-enweghị atụ.

Nyocha nke afọ nwere ike ịgụnye:

• Ultrasound
• Nyocha CT
• MRI
• PET nyocha

Isi ọgwụgwọ bụ ịwa ahụ iji wepu akpụ. ACC nwere ike ọ gaghị emeziwanye na chemotherapy. Enwere ike inye ọgwụ iji belata mmepụta nke cortisol, nke na-akpata ọtụtụ ihe mgbaàmà.

Ihe ga - esi na ya pụta na etu esiri chọpụta nchoputa mbụ yana ma etuto ahụ agbasala (metastasized). Tumor nke gbasaa na-ebutekarị ọnwụ n'ime afọ 1 ruo 3.

Ọrịa ahụ nwere ike ịgbasa na imeju, ọkpụkpụ, akpa ume, ma ọ bụ mpaghara ndị ọzọ.

Kpọọ onye na-ahụ maka ọrụ gị ma ọ bụrụ na gị ma ọ bụ nwa gị nwere mgbaàmà nke ACC, ọrịa Cushing ma ọ bụ enweghị ike itolite.

Tumo - adrenal; ACC - adrenal

• Ọgwụ endocrine
• Adrenal metastases - Nyocha CT
• Adrenal Tumor - CT

Allolio B, Fassnacht M. Adrenocortical carcinoma. Na: Jameson JL, De Groot LJ, de Kretser DM, et al, ndị ọzọ. Endocrinology: Okenye na Ọrịa edimụaka. Nke 7. Philadelphia, PA: Elsevier Saunders; 2016: isi 107.

Weebụsaịtị National Cancer Institute. Adrenocortical carcinoma treatment (Okenye) (PDQ) - ụdị ọkachamara ahụike. www.cancer.gov/types/adrenocortical/hp/adrenocortical-treatment-pdq. Emelitere November 13, 2019. Nweta October 14, 2020.