Gleason grading system

A na - achọpụta ọrịa cancer Prostate mgbe biopsy gasịrị. A na - ewepụta otu ma ọ bụ karịa n’etinye ihe n’ahụ site na prostate wee nyocha ya na microscope.

Sistemụ ngụkọta oge Gleason na-ezo aka n'arịghị ka mkpụrụ ndụ cancer cancer gị dị n'arụ ahụ na etu o si bụrụ na ọrịa cancer ahụ ga-eto ma gbasaa. Akara Gleason dị ala karị pụtara na ọrịa cancer na-aga nwayọ nwayọ ma ọ naghị ewe iwe.

Nzọụkwụ mbụ iji chọpụta ọkwa Gleason bụ ịchọpụta akara Gleason.

1. Mgbe ị na-elele mkpụrụ ndụ n'okpuru microscope, dọkịta na-ekenye mkpụrụ ndụ kansa prostate n'etiti 1 na 5 nọmba (ma ọ bụ ọkwa).
2. Nke a na ọkwa dabere na otu mkpụrụ ndụ ndị ara na-apụta. Ọkwa nke 1 pụtara na mkpụrụ ndụ dị ka mkpụrụ ndụ prostate nkịtị. Ọkwa nke ise pụtara na mkpụrụ ndụ dị ezigbo iche na sel prostate nkịtị.
3. Imirikiti ọrịa kansa prostate nwere mkpụrụ ndụ dị iche iche. N'ihi ya, a na-eji akara abụọ kachasị mma.
4. Akara akara Gleason kpebisiri ike site n'ịgbakwunye akara ule abụọ kachasị. Dịka ọmụmaatụ, klas nke kachasị na mkpụrụ ndụ dị na anụ ahụ nwere ike ịbụ sel nke 3, sel nke sel nke anọ na-esote. Nchịkọta Gleason maka nlele a ga-abụ 7.

Ọnụ ọgụgụ dị elu na-egosi ọrịa kansa na-eto ngwa ngwa nke nwere ike ịgbasa.

Ka ọ dị ugbu a akara kachasị dị ala enyere na akpụ bụ ọkwa 3. Nta akara n'okpuru 3 na-egosi ihe dị nkịtị na nso mkpụrụ ndụ nkịtị. Imirikiti ọrịa cancer nwere akara Gleason (ọnụ ọgụgụ nke akara abụọ kachasị elu) n'etiti 6 (Gleason ọtụtụ nke 3 + 3) na 7 (Gleason ọtụtụ nke 3 + 4 ma ọ bụ 4 + 3).

Mgbe ụfọdụ, ọ nwere ike isiri ike ịkọ otú ndị mmadụ ga-esi mee naanị na ọnụ ọgụgụ Gleason ha naanị.

• Dịka ọmụmaatụ, enwere ike ekenye etuto gị nsonye Gleason nke 7 ma ọ bụrụ na akara abụọ kachasị dị na 3 na 4. 7 nwere ike ịbịa site na ịgbakwunye 3 + 4 ma ọ bụ site na ịtinye 4 + 3.
• Na mkpokọta, onye nwere akara Gleason nke 7 nke na-abịa site na ịgbakwunye 3 + 4 na-enwe mmetụta na ọ nwere obere ọrịa kansa karịa onye nwere akara Gleason nke 7 nke na-abịa site na ịgbakwunye 4 + 3. Nke ahụ bụ n'ihi na onye nwere 4 + 3 = 7 ọkwa nwere mkpụrụ ndụ 4 dị elu karịa sel 3. Sel nke 4 nke ọma na-adịkarị njọ ma yikarịrị ka ọ ga-agbasa karịa sel nke 3.

Emeputara sistemu uzo ohuru nke ise ohuru. Usoro a bụ ụzọ dị mma iji kọwaa etu ọrịa kansa ga-esi eme omume ma meghachi omume na ọgwụgwọ.

• 1 nke otu: akara Gleason 6 ma ọ bụ obere (ọrịa cancer dị ala)
• Otu 2 nke otu: akara Gleason 3 + 4 = 7 (ọkara ọkwa cancer)
• Otu nke 3: akara Gleason 4 + 3 = 7 (cancer ọkara ọkwa)
• Otu 4 nke otu: akara Gleason 8 (ọrịa cancer dị elu)
• Otu nke otu 5: akara Gleason 9 ka 10 (cancer dị elu)

Otu dị ala na-egosi ohere dị mma maka ọgwụgwọ nke ọma karịa otu dị elu. Otu dị elu karị pụtara na ọtụtụ mkpụrụ ndụ cancer na-adị iche na sel ndị nkịtị. Otu dị elu karịa pụtara na o yikarịrị ka etuto ahụ ga-agbasasị ike.

Dingnye ọkwa na-enyere gị na dọkịta gị aka ikpebi usoro ọgwụgwọ gị, yana:

• Oge nke kansa ahụ, nke gosipụtara etu ọrịa kansa ahụ si gbasaa
• Ihe nyocha PSA
• Ahụ ike gị
• Ọchịchọ gị ịwa ahụ, radieshon, ma ọ bụ ọgwụ homonụ, ma ọ bụ enweghị ọgwụgwọ ọ bụla

Oria prostate - Gleason; Adenocarcinoma prostate - Gleason; Gleason ọkwa; Gleason akara; Otu Gleason; Prostate cancer - 5 ọkwa otu

Bostwick DG, Cheng L. Neoplasms nke prostate. N'ime: Cheng L, MacLennan GT, Bostwick DG, eds. Urologic ịwa ahụ Pathology. Agba nke anọ. Philadelphia, PA: Elsevier; 2020: isi 9.

Epstein JI. Ọrịa nke prostate neoplasia.Na: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, ndị ọzọ. Campbell-Walsh-Wein Urology. Agba nke iri na abụọ. Philadelphia, PA: Elsevier; 2021: Isi 151.

Weebụsaịtị National Cancer Institute. Ọgwụ cancer cancer (PDQ) - ụdị ọkachamara ahụike. www.cancer.gov/types/prostate/hp/prostate-treatment-pdq#_2097_toc. Emelitere July 22, 2020. Nweta August 10, 2020.

• Ọrịa Cancer