Metabolic acidosis

Metabolic acidosis bụ ọnọdụ nke enwere nnukwu acid n’ime mmiri mmiri.

Metabolic acidosis na - amalite mgbe etinyere acid n’ime aru. O nwekwara ike ime mgbe akụrụ enweghị ike iwepu acid zuru oke na ahụ. E nwere ọtụtụ ụdị metabolic acidosis:

• Ọrịa shuga (nke a na-akpọkwa ketoacidosis na-arịa ọrịa shuga na DKA) na-amalite mgbe ihe akpọrọ ozu ketone (nke bụ acidic) na-eto eto n'oge ọrịa shuga a na-achịkwaghị achịkwa.
• A na-ebute Hyperchloremic acidosis site na ọnwụ nke sodium bicarbonate dị ukwuu n'ahụ, nke nwere ike ime na afọ ọsịsa siri ike.
• Ọrịa akụrụ (uremia, distal gbasara akụrụ tubular acidosis ma ọ bụ nke a na-enweta nke gbasara akụrụ tubular acidosis).
• Lactic acidosis.
• Nsi ọgwụ aspirin, ethylene glycol na-egbu egbu, ma ọ bụ methanol.
• Oké ịkpọ nkụ.

Lactic acidosis na-esite na ngwunye nke lactic acid. A na-emepụta Lactic acid na mkpụrụ ndụ akwara na mkpụrụ ndụ ọbara uhie. Ọ na - etolite mgbe ahụ mebiri carbohydrates iji rụọ ọrụ maka ike mgbe ikuku oxygen dị ala. Enwere ike kpatara ya:

• Ọrịa cancer
• Nsi nsi carbon monoxide
• Ụbiga mmanya ókè
• Na-emega ahụ ike ruo ogologo oge
• Ọkpụkpụ imeju
• Ọbara dị n'ọbara (hypoglycemia)
• Ọgwụ, dịka salicylates, metformin, anti-retrovirals
• MELAS (ọrịa mkpụrụ ndụ mkpụrụ ndụ mitochondrial dị obere nke na-emetụta mmepụta ume)
• Enweghị oxygen ruo ogologo oge site na ujo, nkụda obi, ma ọ bụ oke anaemia
• Ọdịdọ

Imirikiti ihe mgbaàmà na-akpata ọrịa na-akpata ọrịa ma ọ bụ ọnọdụ na-akpata metabolic acidosis. Metabolic acidosis n’onwe ya na-ebutekarị ume ngwa ngwa. Ime ihe mgbagwoju anya ma ọ bụ ike gwụrụ nwekwara ike ime. Oké metabolic acidosis nwere ike ibute ujo ma ọ bụ ọnwụ. N'ọnọdụ ụfọdụ, metabolic acidosis nwere ike ịbụ ọnọdụ dị nro, na-aga n'ihu (ala ala).

Nlere ndị a nwere ike inyere aka ịchọpụta acidosis. Ha nwekwara ike ịchọpụta ma ihe kpatara ya bụ nsogbu iku ume ma ọ bụ nsogbu metabolic. Ule nwere ike ịgụnye:

• Ọbara ọbara ọbara
• Basic metabolic panel, (otu ule ọbara na-atụle sodium na potassium ọkwa gị, ọrụ akụrụ, na ọgwụ ndị ọzọ na ọrụ)
• Ketones nke ọbara
• Nnwale Lactic acid
• Mmiri ketere
• Mmamịrị pH

Enwere ike ịchọ nyocha ndị ọzọ iji chọpụta ihe kpatara acidosis.

A na-eji ọgwụgwọ eme ihe maka nsogbu ahụike na-akpata acidosis. N'ọnọdụ ụfọdụ, enwere ike inye sodium bicarbonate (mmiri ọgwụ dị na soda) iji belata acidity nke ọbara. Ọtụtụ mgbe, ị ga-enweta ọtụtụ mmiri site na akwara gị.

Echiche ga-adabere na ọrịa na-akpata ọrịa na-akpata ọnọdụ ahụ.

Nnukwu metabolic acidosis nwere ike ibute ujo ma ọ bụ ọnwụ.

Chọọ enyemaka ahụike ma ọ bụrụ na ị nwere mgbaàmà nke ọrịa ọ bụla nwere ike ibute metabolic acidosis.

Enwere ike igbochi ọrịa shuga ketoacidosis site na ijide ụdị ọrịa shuga nke ụdị 1.

Acidosis - metabolic

• Mmepụta insulin na ọrịa shuga

Hamm LL, DuBose TD. Ọgba aghara nke acid-base balance. Na: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner na Rector nke akụrụ. Nke 11. Philadelphia, PA: Elsevier; 2020: isi 16.

Palmer BF. Metabolic acidosis. Na: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Comprehensive Clinical Nephrology. Nke isii. Philadelphia, PA: Elsevier; 2019: isi 12.

Nke anọ JL. Ọrịa Acid-base. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke 26th. Philadelphia, PA: Elsevier; 2020: isi 110.