Pulmonary alveolar na-enye nsogbu

Pulmonary alveolar proteinosis (PAP) bụ ọrịa na-adịghị ahụkebe nke ụdị protein na-eto n'ime akpa ikuku (alveoli) nke ngụgụ, na-eme ka iku ume sie ike. Pulmonary pụtara metụtara ngụgụ.

N'ọnọdụ ụfọdụ, ihe kpatara PAP amaghị. Na ndị ọzọ, ọ na-ebute ọrịa n'akpa ume ma ọ bụ nsogbu mgbochi. O nwekwara ike ime na ọrịa cancer nke usoro ọbara, na mgbe ekpughere ya n'ọtụtụ dị elu nke gburugburu ebe obibi, dịka silica ma ọ bụ ájá aluminom.

Ndị nọ n’agbata afọ 30 na 50 na-emetakarkarị ya. A na-ahụ PAP na ụmụ nwoke karịa ụmụ nwanyị. Formdị nsogbu a dị n'oge ọmụmụ (congenital).

Mgbaàmà nke PAP nwere ike ịgụnye nke ọ bụla n'ime ihe ndị a:

• Iku ume ọkụ ọkụ
• .Kwara
• Ike ọgwụgwụ
• Ahụ ọkụ, ma ọ bụrụ na e nwere ọrịa ngụgụ
• Akpụkpọ anụ Bluish (cyanosis) n'ọnọdụ ndị siri ike
• Iwetulata ibu

Mgbe ụfọdụ, enweghi mgbaàmà ọ bụla.

Onye nlekọta ahụike ga-eji stethoscope gee ntị na ngụgụ ma ọ nwere ike ịnụ mgbape (rales) na ngụgụ. Ọtụtụ mgbe, nyocha anụ ahụ bụ ihe nkịtị.

Enwere ike ịme ule ndị a:

• Bronchoscopy na nnu nnu nke ngụgụ (lavage)
• Igbe x-ray
• Nyocha CT nke igbe
• Ume ọrụ ule
• Meghee biopsy biopsy (ịwa ahụ biopsy)

Ọgwụgwọ gụnyere ịsachasị ihe protin sitere n’akpa ume (ume iku ume) site n’oge ruo n’oge. Fọdụ ndị mmadụ nwere ike ịchọ ịmịnye ngụgụ. A na-atụ aro izere ájá nke nwere ike ịkpata ọnọdụ ahụ.

Usoro ọgwụgwọ ọzọ enwere ike ịnwale bụ ọgwụ na-akpali akpali nke akpọrọ granulocyte-macrophage colony na-akpali akpali (GM-CSF), nke na-enweghị ụfọdụ ndị nwere proteosis alveolar.

Ihe omuma ndi a nwere ike inye ndi ozo banyere PAP:

• Organizationtù Mba Maka Ọrịa Na-adịghị - rarediseases.org/rare-diseases/pulmonary-alveolar-proteinosis
• PAP Foundation - www.papfoundation.org

Peoplefọdụ ndị nwere PAP na-abanye na mgbaghara. Ndị ọzọ nwere mbelata ọrịa ngụgụ (iku ume iku ume) nke na-akawanye njọ, ha nwekwara ike ịchọ ịmịnye ngụgụ.

Kpọọ onye na-eweta ọrụ gị ma ọ bụrụ na ị mepee mgbaàmà iku ume siri ike. Ofku ume ọkụ ọkụ nke na-akawanye njọ ka oge na-aga nwere ike igosi na ọnọdụ gị na-aghọ ihe mberede ọgwụ.

PAP; Alveolar proteinosis; Pulmonary alveolar phospholipoproteinosis; Ọbara akpa ume; Alveolar lipoproteinosis phospholipidosis

• Ọrịa akpa ume Interstitial - ndị okenye - ihapu

• Usoro iku ume

Levine SM. Nsogbu ndochi Alveolar. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke 26th. Philadelphia, PA: Elsevier; 2020: isi 85.

Trapnell BC, Luisetti M. Pulmonary syndrome na-arịa ọrịa ogbu na nkwonkwo. Na: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Akwụkwọ ọgụgụ Murray na Nadel nke Medicine Respiratory. Nke isii. Philadelphia, PA: Elsevier Saunders; 2016: isi 70.