PTEN Genetic Ule

Ndinaya

• Kedu ihe bụ ule mkpụrụ ndụ ihe nketa?
• Kedu ihe eji ya?
• Kedu ihe kpatara m ji chọọ nyocha mkpụrụ ndụ ihe nketa PTEN?
• Kedu ihe na-eme n'oge ule mkpụrụ ndụ ihe nketa PTEN?
• Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?
• Onwere ihe egwu di n’ule a?
• Kedu ihe nsonaazụ ahụ pụtara?
• Onwere ihe ozo ichoro ima banyere PTEN genetic test?
• Ntughari

Kedu ihe bụ ule mkpụrụ ndụ ihe nketa?

PTEN mkpụrụ ndụ ihe nketa na-achọ mgbanwe, nke a maara dị ka mmụba, na mkpụrụ ndụ ihe nketa a na-akpọ PTEN. Ihe nketa bụ ihe nketa sitere n'aka nne gị na nna gị.

Mkpụrụ ndụ PTEN na-enyere aka ịkwụsị uto nke etuto ahụ. A maara ya dị ka ebelata tumo. Mkpụrụ ụbụrụ na-ebelata ụbụrụ dị ka brek na ụgbọ ala. Ọ na-etinye "brek" na sel, n'ihi ya, ha anaghị ekewa ngwa ngwa. Ọ bụrụ na ị nwere mkpụrụ ndụ mkpụrụ ndụ ihe nketa PTEN, ọ nwere ike ibute uto nke etuto ahụ na-abụghị nke a na-akpọ hamartomas. Hamartomas nwere ike igosipụta ahụ niile. Mgbanwe ahụ nwekwara ike iduga mmepe nke akpụ cancer.

PTEN mkpụrụ ndụ ihe nketa nwere ike iketa n'aka nne na nna gị, ma ọ bụ nweta ya n'ọdịnihu na gburugburu ebe obibi ma ọ bụ site na ndudue nke na-eme n'ahụ gị n'oge cell nkewa.

Mgbanwe PTEN a ketara eketa nwere ike ibute ọtụtụ nsogbu ahụike. Offọdụ n’ime ha nwere ike ịmalite mgbe ha bụ ụmụ ọhụrụ ma ọ bụ n’oge ha bụ ụmụaka. Ndị ọzọ na-apụta mgbe ha toro eto. A na - ejikọkarị nsogbu ndị a ma kpọọ PTEN hamartoma syndrome (PTHS) ma gụnye ya:

• Ọrịa Cowden, ọgba aghara nke na - ebute uto nke ọtụtụ hamartomas ma na - eme ka ohere dị iche iche nke kansa dị iche iche, gụnyere kansa nke ara, akpanwa, thyroid, na colon. Ndị mmadụ na-arịa ọrịa Cowden na-enwekarị ibu buru ibu karịa (macrocephaly), igbu oge, na / ma ọ bụ autism.
• Ọrịa Bannayan-Riley-Ruvalcaba na-emekwa ka hamartomas na macrocephaly. Na mgbakwunye, ndị nwere ọrịa a nwere ike ịnwe nkwarụ ọmụmụ na / ma ọ bụ autism. Mụ nwoke nwere nsogbu a na-enwekarị ntụpọ ojii na amụ.
• Proteus ma ọ bụ Proteus-dị ka ọrịa nwere ike ime ka okpukpu buru ibu nke ọkpụkpụ, anụ ahụ, na anụ ahụ ndị ọzọ, yana hamartomas na macrocephaly.

Enwetara (nke a makwaara dị ka somatic) PTEN mkpụrụ ndụ ihe nketa bụ otu n'ime mgbanwe ndị a na-ahụkarị na ọrịa kansa mmadụ. Achọpụtala mmụba a n'ọtụtụ ọrịa kansa dị iche iche, gụnyere kansa prostate, cancer akpa nwa, na ụfọdụ ụdị etuto ụbụrụ.

Aha ndị ọzọ: mkpụrụ ndụ PTEN, nyocha usoro zuru ezu; PTEN usoro na nhichapụ / mbiputegharị

Kedu ihe eji ya?

A na-eji ule ahụ chọọ maka mkpụrụ ndụ mkpụrụ ndụ ihe nketa PTEN. Ọ bụghị ule a na-eme mgbe niile. A na-enyekarị ya ndị mmadụ dabere na akụkọ ntolite ezinụlọ, mgbaàmà, ma ọ bụ nchọpụta mbụ nke kansa, ọkachasị kansa nke ara, thyroid, ma ọ bụ akpanwa.

Kedu ihe kpatara m ji chọọ nyocha mkpụrụ ndụ ihe nketa PTEN?

Gị ma ọ bụ nwa gị nwere ike ịchọ nyocha mkpụrụ ndụ ihe nketa PTEN ma ọ bụrụ na ị nwere akụkọ ihe mere eme nke ezinụlọ gbasara mkpụrụ ndụ mkpụrụ ndụ PTEN na / ma ọ bụ otu ma ọ bụ karịa n'ime ọnọdụ ma ọ bụ ihe mgbaàmà ndị a:

• Otutu hamartomas, karịsịa na mpaghara eriri afọ
• Macrocephaly (buru ibu karịa isi)
• Ọganihu mmepe
• Autism
• Ọchịchịrị nke amụ na amụ
• Ọrịa ara ure
• Ọrịa thyroid gị
• Uterine cancer na nwanyị

Ọ bụrụ na achọpụtala gị na kansa na enweghị ezinụlọ akụkọ ihe mere eme nke ọrịa ahụ, onye na-ahụ maka ahụike gị nwere ike ịnye nyocha a iji hụ ma PTEN mkpụrụ ndụ ihe nketa nwere ike ịkpata kansa gị. Mara ma ị nwere mmụba ahụ nwere ike inyere onye na-eweta gị aka ịkọ etu ọrịa gị ga-esi tolite ma duzie ọgwụgwọ gị.

Kedu ihe na-eme n'oge ule mkpụrụ ndụ ihe nketa PTEN?

Nyocha PTEN na-abụkarị nyocha ọbara. N'oge ule ọbara, onye ọkachamara ahụike ga-ewere ihe nyocha ọbara site na akwara aka gị, na-eji obere agịga. Mgbe etinyere agịga ahụ, a ga-achịkọta obere ọbara n'ime ule nyocha ma ọ bụ vial. Nwere ike na-eche ntakịrị ihe mgbe agịga na-abanye ma ọ bụ na-apụta. Nke a na-ewe ihe na-erughị nkeji ise.

Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?

Usually naghị achọkarị nkwadebe ọ bụla pụrụ iche maka ule PTEN.

Onwere ihe egwu di n’ule a?

O nwechaghị ihe egwu dị n’inyocha ọbara. May nwere ike ịnwe obere ihe mgbu ma ọ bụ mmerụ ahụ ebe etinyere agịga ahụ, mana ọtụtụ mgbaàmà na-apụ ngwa ngwa.

Kedu ihe nsonaazụ ahụ pụtara?

Ọ bụrụ na nsonaazụ gị gosiri na ị nwere mkpụrụ ndụ mkpụrụ ndụ ihe nketa PTEN, ọ pụtaghị na ị nwere kansa, mana ihe egwu gị dị elu karịa ọtụtụ mmadụ. Mana nyocha ọrịa kansa ugboro ugboro nwere ike belata ihe egwu gị. Ọrịa cancer nwere ike ịgwọ karịa mgbe achọtara ya na mbido. Ọ bụrụ n ’ị nwere mmụgharị, onye nlekọta ahụike gị nwere ike ịkwado otu ma ọ bụ karịa n’ime ule nyocha ndị a:

• Colonoscopy, malite na afọ 35-40
• Mammogram, malite na afọ iri atọ maka ụmụ nwanyị
• Nyocha nwa oge ara nke ụmụ nwanyị
• Nyocha umu nwanyi maka nwanyi
• Nyocha kwa afọ
• Nyocha kwa afọ maka akpụkpọ ahụ
• Nyocha akụrụ afọ

A na-atụ aro ọgwụ mgbochi ọrịa thyroid na anụ ahụ maka ụmụaka nwere mkpụrụ ndụ mkpụrụ ndụ ihe nketa PTEN.

Mụtakwuo maka ule nyocha ụlọ, akara ngosi, na nghọta nsonaazụ.

Onwere ihe ozo ichoro ima banyere PTEN genetic test?

Ọ bụrụ na achọpụtala na PTEN mkpụrụ ndụ ihe nketa ma ọ bụ na-eche echiche ịnwale, ọ nwere ike inye aka ịgwa onye na-enye ndụmọdụ gbasara mkpụrụ ndụ ihe nketa. Onye ndụmọdụ banyere mkpụrụ ndụ ihe nketa bụ ọkachamara a zụrụ azụ na mkpụrụ ndụ ihe nketa na ule mkpụrụ ndụ. Ọ bụrụ na ịnwalebeghị gị, onye ndụmọdụ nwere ike inyere gị aka ịghọta ọghọm na uru elele. Ọ bụrụ na anwalela gị, onye ndụmọdụ ahụ nwere ike inyere gị aka ịghọta nsonaazụ ya wee duzie gị ịkwado ọrụ na akụrụngwa ndị ọzọ.

Ntughari

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Ejila ozi dị na saịtị a dị ka onye dochie anya nlekọta ahụike ọkachamara ma ọ bụ ndụmọdụ. Kpọtụrụ onye na-ahụ maka ahụike ma ọ bụrụ na ị nwere ajụjụ gbasara ahụike gị.