Hemoglobin Electrophoresis

Ndinaya

• Gini bụ electromforesis hemoglobin?
• Kedu ihe eji ya?
• Kedu ihe kpatara m ji chọọ hemoglobin electrophoresis?
• Kedu ihe na - eme n'oge hemoglobin electrophoresis?
• Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?
• There nwere ihe ọghọm dị na hemoglobin electrophoresis?
• Kedu ihe nsonaazụ ahụ pụtara?
• Onwere ihe ozo m choro ima banyere hemoglobin electrophoresis?
• Ntughari

Gini bụ electromforesis hemoglobin?

Hemoglobin bụ protein dị n’ọbara gị ọbara uhie nke na-eburu oxygen site n’akpa ume gị ruo n’akụkụ ahụ gị ndị ọzọ. E nwere ọtụtụ haemoglobin dị iche iche. Hemoglobin electrophoresis bụ ule nke na-atụle ụdị haemoglobin dị n’ọbara. Ọ na-achọkwa ụdị haemoglobin na-adịghị mma.

Maldị hemoglobin nkịtị gụnyere:

• Hemoglobin (Hgb) A, ụdị ụdị haemoglobin kachasị na ndị okenye toro eto
• Hemoglobin (Hgb) F, hemoglobin nwa ebu n’afọ. Typedị hemoglobin a na - ahụ ụmụ amụrụ ọhụrụ na ụmụ amụrụ ọhụrụ. HgbF dochie HgbA obere oge amuchara nwa.

Ọ bụrụ na ọkwa nke HgbA ma ọ bụ HgbF dị oke elu ma ọ bụ dị obere, ọ nwere ike igosi ụfọdụ ụdị anaemia.

Typesdị hemoglobin na-adịghị mma gụnyere:

• Hemoglobin (Hgb) S. Founddị hemoglobin a dị n'ọrịa sickle cell. Ọrịa Sickle cell bụ nsogbu a na-eketa nke na-eme ka ahụ nwee ike ime mkpụrụ ndụ ọbara uhie yiri nke sickle. Ahụ ike ọbara ọbara uhie na-agbanwe agbanwe ka ha nwee ike ịgafe n'ụzọ dị mfe site na arịa ọbara. Mkpụrụ ndụ Sickle nwere ike ịrapara na akwara ọbara, na-ebute oke mgbu ma na-adịghị ala ala, ọrịa, na nsogbu ndị ọzọ.
• Hemoglobin (Hgb) C. Typedị haemoglobin a anaghị ebunye ikuku oxygen nke ọma. Ọ nwere ike ibute ụdị ọrịa anaemia dị nro.
• Hemoglobin (Hgb) E. Isdị hemoglobin a na-ahụkarị na ndị bi na Ndịda Ebe Ọwụwa Anyanwụ Eshia. Ndị mmadụ HgbE anaghị enwekarị mgbaàmà ma ọ bụ ihe mgbaàmà dị ala nke anaemia.

Ihe nyocha electromhoresis hemoglobin na-emetụta eletrik na ntanetị ọbara. Nke a na - ekewa ụdị haemoglobin dị mma na adịghị mma. Enwere ike ịtụ ụdị hemoglobin ọ bụla n'otu n'otu.

Aha ndị ọzọ: Hb electrophoresis, hemoglobin evaluation, hemoglobinopathy evaluation, hemoglobin fractionation, Hb ELP, sickle cell screen

Kedu ihe eji ya?

Hemoglobin electrophoresis na-agbanye ogo hemoglobin ma na-achọ ụdị adịghị mma nke haemoglobin. A na-ejikarị ya iji nyere aka chọpụta ọrịa anaemia, ọrịa sickle cell, na nsogbu ndị ọzọ haemoglobin.

Kedu ihe kpatara m ji chọọ hemoglobin electrophoresis?

Nwere ike ịnwale ma ọ bụrụ na ị nwere mgbaàmà nke ọrịa hemoglobin. Ndị a gụnyere:

• Ike ọgwụgwụ
• Icha akpụkpọ
• Jaundice, bu ihe n’eme ka akpukpo aru ya na anya gha acha odo
• Oké ihe mgbu (ọrịa sickle cell)
• Nsogbu uto (n'ime ụmụaka)

Ọ bụrụ na ị ka mụrụ nwa, a ga-anwale nwa amụrụ ọhụrụ gị dị ka akụkụ nke nyocha ọhụụ. Nyocha nwa amụrụ ọhụrụ bụ otu ule a na-enye ọtụtụ ụmụaka ndị America obere oge amụrụ ha. Nyocha nyocha maka ọnọdụ dị iche iche. Enwere ike ịgwọ ọtụtụ n'ime ọnọdụ ndị a ma ọ bụrụ na achọta n'oge.

Nwekwara ike chọọ ịnwale ma ọ bụrụ na ịnọ n'ihe egwu maka ịmụ nwa nwere ọrịa sickle cell ma ọ bụ ọrịa hemoglobin ọzọ ketara eketa. Ihe egwu nwere:

• Akụkọ banyere ezinụlọ
• Agbụrụ
  • Na United States, ọtụtụ ndị nwere ọrịa sickle cell bụ ndị nna ochie Africa.
  • Thalassaemia, ọrịa hemoglobin ọzọ ketara eketa, bụ nke a na-ahụkarị n’etiti ndị Italiantali, Grik, Middle Eastern, Southern Asia, na Africa.

Kedu ihe na - eme n'oge hemoglobin electrophoresis?

Onye ọkachamara ahụike ga-ewere ihe nyocha ọbara site na akwara aka gị, jiri obere agịga. Mgbe etinyere agịga ahụ, a ga-achịkọta obere ọbara n'ime ule nyocha ma ọ bụ vial. Nwere ike na-eche ntakịrị ihe mgbe agịga na-abanye ma ọ bụ na-apụta. Nke a na-ewe ihe na-erughị nkeji ise.

Iji nwalee nwa amụrụ ọhụrụ, onye nlekọta ahụike ga-ehichapụ ikiri ụkwụ nwa gị mmanya na-aba n’anya ma jiri obere agịga zọọ ikiri ụkwụ. Onye na-eweta ya ga-anakọta ọbara ọbara ole na ole ma tinye bandeeji na saịtị ahụ.

Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?

Kwesighi nkwadebe ọ bụla pụrụ iche maka ule hemoglobin electrophoresis.

There nwere ihe ọghọm dị na hemoglobin electrophoresis?

O nwechaghị ihe egwu dị n’inyocha ọbara. May nwere ike ịnwe obere ihe mgbu ma ọ bụ mmerụ ahụ ebe etinyere agịga ahụ, mana ọtụtụ mgbaàmà na-apụ ngwa ngwa.

Nwa gị nwere ike na-eche na ọ ga-adị obere mgbe ọkpọkọ ya ikiri ụkwụ, obere ọnya nwere ike ịdị na saịtị ahụ. Nke a kwesịrị ịpụ ngwa ngwa.

Kedu ihe nsonaazụ ahụ pụtara?

Nsonaazụ gị ga-egosi ụdị hemoglobin a hụrụ na ọkwa nke ọ bụla.

Hemoglobin ọkwa nke dị elu ma ọ bụ dị ala nwere ike ịpụta:

• Thalassaemia, ọnọdụ na-emetụta mmepụta nke hemoglobin. Mgbaàmà sitere na nwayọọ ruo oke.
• Àgwà Sickle cell. Na ọnọdụ a, ịnwere otu mkpụrụ ndụ ihe odide sickle cell na otu mkpụrụ ndụ ihe nketa dị mma. Imirikiti ndị nwere àgwà sickle cell enweghị nsogbu ahụike.
• Ọrịa Sickle cell
• Ọrịa Hemoglobin C, ọnọdụ nke na-akpata ụdị ọrịa anaemia dị nro na mgbe ụfọdụ mgbatị na-ebuwanye ibu na nkwonkwo
• Hemoglobin SC ọrịa, ọnọdụ nke na-akpata ụdị adịghị mma nke sickle cell

Nsonaazụ gị nwekwara ike igosi ma otu nsogbu dị nro, nke siri ike, ma ọ bụ nke siri ike.

A na-ejikarị nsonaazụ Hemoglobin electrophoresis mee ihe na nyocha ndị ọzọ, gụnyere nyocha ọbara zuru oke na ọbara. Ọ bụrụ na ị nwere ajụjụ gbasara nsonaazụ gị, gwa ndị ọrụ ahụike gị okwu.

Mụtakwuo maka ule nyocha ụlọ, akara ngosi, na nghọta nsonaazụ.

Onwere ihe ozo m choro ima banyere hemoglobin electrophoresis?

Ọ bụrụ na ị nọ n’ihe egwu ịmụ nwa nwere ọrịa hemoglobin a ketara eketa, ị nwere ike ịgwa onye na-enye ndụmọdụ gbasara mkpụrụ ndụ ihe nketa. Onye ndụmọdụ banyere mkpụrụ ndụ ihe nketa bụ ọkachamara a zụrụ azụ na mkpụrụ ndụ ihe nketa na ule mkpụrụ ndụ. Ọ nwere ike inyere gị aka ịghọta nsogbu ahụ na ihe egwu ị na-enyefe nwa gị.

Ntughari

1. American Society nke Hematology [Internet]. Washington DC: American Society nke Hematology; Agugu 2020. Ọrịa Sickle Cell; [akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://www.hematology.org/Patients/Anemia/Sickle-Cell.aspx
2. Velọ Ọgwụ Cleveland [Internet]. Cleveland (OH): velọ Ọgwụ Cleveland; Agugu 2020. Sickle Cell Anemia: Nchịkọta; [akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://my.clevelandclinic.org/health/diseases/4579-sickle-cell-anemia
3. Ahụike Kidsmụaka site na Nemours [Internet]. Jacksonville (FL): Nemours Foundation; C1995–2020. Ule ọbara: Hemoglobin Electrophoresis; [akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://kidshealth.org/en/parents/test-electrophoresis.html
4. Nnwale ụlọ nyocha na ntanetị [Intanet]. Washington DC: American Association maka Clinical Chemistry; C2001–2020. Nyocha Hemoglobinopathy; [emelitere 2019 Sep 23; akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 2]. Odi na: https://labtestsonline.org/tests/hemoglobinopathy-evaluation
5. Nnwale ụlọ nyocha na ntanetị [Intanet]. Washington DC: American Association maka Clinical Chemistry; C2001–2020. Jaundice; [emelitere 2019 Oct 30; akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://labtestsonline.org/conditions/jaundice
6. Machị nke Dimes [Internet]. Arlington (VA): Machị nke Dimes; Agugu 2020. Nwa amụrụ ọhụrụ amụrụ nwa ọhụrụ; [akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://www.marchofdimes.org/baby/newborn-screening-tests-for-your-baby.aspx
7. Merck Manual Consumer Version [Intanet]. Kenilworth (NJ): Merck & Co. Inc.; 2020. Hemoglobin C, SC, na Ọrịa E; [emelitere 2019 Feb; akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://www.merckmanuals.com/home/blood-disorders/anemia/hemoglobin-c,-s-c,-and-e-diseases?query=hemoglobin%20electrophoresis
8. National Heart, Lung, na Ọbara Institute [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Nnwale ọbara; [akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://www.nhlbi.nih.gov/health-topics/blood-tests
9. National Heart, Lung, na Ọbara Institute [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Ọrịa Sickle Cell; [akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://www.nhlbi.nih.gov/health-topics/sickle-cell-disease
10. National Heart, Lung, na Ọbara Institute [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Thalassaima; [akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 3]. O nwere site na: https://www.nhlbi.nih.gov/health-topics/thalassemias
11. Ahụike UF: Mahadum nke Florida Health [Internet]. Gainesville (FL): Mahadum nke Florida Health; Agugu 2020. Hemoglobin electrophoresis: Nchịkọta; [emelitere 2020 Jan 10; akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 2]. Nweta ya site na: https://ufhealth.org/hemoglobin-electrophoresis
12. Ahụike UW [Internet]. Madison (WI): Mahadum nke Wisconsin italslọọgwụ na Clinics Authority; Agugu 2020. Ozi ahụike: Hemoglobin Electrophoresis: Nsonaazụ; [emelitere 2019 Mar 28; akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 8]. O nwere site na: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html#hw39128
13. Ahụike UW [Internet]. Madison (WI): Mahadum nke Wisconsin italslọọgwụ na Clinics Authority; Agugu 2020. Ozi Ahụ Ike: Hemoglobin Electrophoresis: Nnwale Nleba; [emelitere 2019 Mar 28; akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html
14. Ahụike UW [Internet]. Madison (WI): Mahadum nke Wisconsin italslọọgwụ na Clinics Authority; Agugu 2020. Ozi Ahụ Ike: Hemoglobin Electrophoresis: Ihe Think Ga-eche Banyere; [emelitere 2019 Mar 28; akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 10]. O nwere site na: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html#hw39144
15. Ahụike UW [Internet]. Madison (WI): Mahadum nke Wisconsin italslọọgwụ na Clinics Authority; Agugu 2020. Ozi Ahụ Ike: Hemoglobin Electrophoresis: Ihe Mere E Ji Eme Ya; [emelitere 2019 Mar 28; akpọrọ 2020 Jan 10]; [ihe dị ka ihuenyo 3]. O nwere site na: https://www.uwhealth.org/health/topic/medicaltest/hemoglobin-electrophoresis/hw39098.html#hw39110

Ejila ozi dị na saịtị a dị ka onye dochie anya nlekọta ahụike ọkachamara ma ọ bụ ndụmọdụ. Kpọtụrụ onye na-ahụ maka ahụike ma ọ bụrụ na ị nwere ajụjụ gbasara ahụike gị.