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Gịnị bụ beta-2 microglobulin akpụ welara ule?

Nnwale a na-atụle ego protein a na-akpọ beta-2 microglobulin (B2M) n'ime ọbara, mmamịrị, ma ọ bụ cerebrospinal fluid (CSF). B2M bụ ụdị akara nrịanrịa. Tumor ihe nrịba ama bu ihe nke mkpuru cancer ma obu site na nkpuru aru kwesiri iji mee ihe banyere oria aru nke aru.

A na - ahụ B2M n’elu ọtụtụ sel ma wepụta ya n’ime ahụ. Ndị ahụike siri ike nwere obere B2M n’ọbara na mmamịrị ha.

  • Ndị mmadụ nwere ọrịa kansa nke ụmị ọkpụkpụ na ọbara na-enwekarị nnukwu B2M n'ọbara ha ma ọ bụ mamịrị ha. Ọrịa ndị a gụnyere ọtụtụ myeloma, lymphoma, na leukemia.
  • Nnukwu nke B2M na cerebrospinal ọmụmụ nwere ike ịpụta na ọrịa kansa agbasaala ụbụrụ na / ma ọ bụ ọgidigi azụ.

Ejighị ule akara ọnya B2M iji chọpụta ọrịa kansa. Mana ọ nwere ike inye ozi dị mkpa gbasara kansa gị, gụnyere etu o siri dị njọ na otu ọ nwere ike isi tolite n’ọdịnihu.

Aha ndị ọzọ: ngụkọta beta-2 microglobulin, β2-microglobulin, B2M


Kedu ihe eji ya?

A na-enyekarị ndị mmadụ nyochala ụfọdụ ọrịa kansa nke ụmị ọkpụkpụ ma ọ bụ ọbara beta-2 microglobulin marker. Ule ahụ nwere ike iji:

  • Chọpụta oke ọrịa kansa na-agbasa. A maara usoro a dị ka ọrịa cancer. Ọkwa dị elu karịa ka ọ na - arị elu.
  • Buru amụma banyere mmepe ọrịa ma duzie ọgwụgwọ.
  • Hụ ma ọgwụgwọ ọrịa kansa ọ dị mma.
  • Hụ ma ọ bụrụ na ọrịa kansa agbasawo ụbụrụ na ụbụrụ.

Kedu ihe kpatara m ji chọọ nyocha ihe nrịbama beta-2 microglobulin?

Nwere ike ịnwale ule a ma ọ bụrụ na achọpụtala na ị nwere ọtụtụ myeloma, lymphoma, ma ọ bụ leukemia. Nnwale ahụ nwere ike igosi ọkwa nke kansa gị yana ọgwụgwọ ịgwọ ọrịa kansa gị ọ na-arụ ọrụ.

Kedu ihe na - eme n'oge ule beta-2 microglobulin marker test?

Nyocha beta-2 microglobulin na-abụkarị nyocha ọbara, mana enwere ike ịnye ya dị ka ule mmamịrị elekere 24, ma ọ bụ dịka nyocha nke cerebrospinal fluid (CSF).


Maka ule ọbara, onye okacha amara nke ahuike ga ewere obara site na akwara na ogwe aka gi. Mgbe etinyere agịga ahụ, a ga-achịkọta obere ọbara n'ime ule nyocha ma ọ bụ vial. Nwere ike na-eche ntakịrị ihe mgbe agịga na-abanye ma ọ bụ na-apụta. Nke a na-ewe ihe na-erughị nkeji ise.

Maka 24 awa awa mmamịrị, onye na ahu maka ahu ike gi ma obu onye nyocha nke ulo ogwu gha enye gi akpa iji kpoko mmamiri gi na ntuzi aka banyere otu esi achikota ma chekwaa ihe nlere gi. Nyocha 24 hour nke mmamịrị na-agụnye usoro ndị a:

  • Wepụ eriri afo gị n'ụtụtụ ma wepụ mamịrị ahụ. Dekọọ oge.
  • Maka awa 24 na-esote, chekwaa mamịrị gị niile n'ime akpa enyere.
  • Chekwaa akpa mamịrị gị n'ime ngwa nju oyi ma ọ bụ oyi nwere ice.
  • Weghachite ihe nlele ahụ na ụlọ ọrụ ahụike gị ma ọ bụ ụlọ nyocha dị ka enyere gị iwu.

Maka nyocha nke mmiri ọgwụ (CSF), a ga-anakọta ihe ọmụmụ nke mmiri ọgwụ azụ na usoro a na-akpọ ọkpọ azụ (nke a makwaara dị ka oghere lumbar). A na-arụkarị ọkpọ azụ na ụlọ ọgwụ. N'oge usoro ahụ:


  • Ga-edina n’akụkụ gị ma ọ bụ ịnọdụ ala na tebụl nyocha.
  • Onye na-ahụ maka ahụike ga-ehicha azụ gị ma tinye anestetiiki na akpụkpọ gị, yabụ na ị gaghị enwe ihe mgbu n'oge usoro ahụ. Onye na-eweta gị nwere ike itinye ude na-agwụ ike n’azụ gị tupu ogwu a.
  • Ozugbo akụrụngwa dị n'azụ gị zuru oke, onye na-eweta gị ga-etinye agịga dị warara, nke dị oghere n'etiti mkpịsị ụkwụ abụọ na azụ ala gị. Vertebrae bụ obere ọkpụkpụ na-eme ka ọkpụkpụ azụ gị.
  • Onye na-enye gị ga-ewepụ obere mmiri cerebrospinal ọmụmụ maka ule. Nke a ga-ewe ihe dịka nkeji ise.
  • Ọ ga-adị mkpa ka ị nọrọ jụụ ka a na-ewepụ mmiri mmiri.
  • Onye na-eweta gị nwere ike ịrịọ gị ka ị dina n’azụ gị otu elekere ma ọ bụ abụọ mgbe emechara ya. Nke a nwere ike igbochi gị ịnweta isi ọwụwa mgbe emechara.

Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?

Don’tkwesighi nkwadebe ọ bụla pụrụ iche maka nyocha ọbara ma ọ bụ mmamịrị.

Youchọghị nkwadebe ọ bụla pụrụ iche maka nyocha CSF, mana enwere ike ịgwa gị ka iwepụ eriri afọ gị na eriri afọ gị tupu ule ahụ.

Onwere ihe egwu di n’ule a?

O nwechaghị ihe egwu n’inwe ọbara ma ọ bụ mmamịrị. Mgbe nyochachara ọbara, ị nwere ike ịnwe obere ihe mgbu ma ọ bụ nchihịa ebe a na-etinye agịga ahụ, mana ọtụtụ mgbaàmà na-apụ ngwa ngwa.

Ọ dị obere ihe egwu nwere ịnweta ọkpọ azụ. Nwere ike ịnwe ntakịrị tuo ma ọ bụ nrụgide mgbe etinyere agịga ahụ. Mgbe ule ahụ gasịrị, ị nwere ike ịnweta isi ọwụwa, nke a na-akpọ isi ọwụwa post-lumbar. Ihe dị ka otu onye n’ime mmadụ iri ọ bụla ga-enweta isi ọwụwa post-lumbar. Nke a nwere ike ịdịru ọtụtụ awa ma ọ bụ ruo otu izu ma ọ bụ karịa. Ọ bụrụ na ị nwere isi ọwụwa nke dị ogologo karịa ọtụtụ awa, gwa onye na-ahụ maka ahụike gị. O nwere ike inye ọgwụgwọ iji belata ihe mgbu ahụ. Nwere ike ịnwe ụfọdụ ihe mgbu ma ọ bụ nro na azụ gị na saịtị ebe etinyere agịga ahụ. Nwekwara ike ịnwe ọbara ọgbụgba na saịtị ahụ.

Kedu ihe nsonaazụ ahụ pụtara?

Ọ bụrụ na ejiri nyocha ahụ chọpụta etu ọrịa kansa gị dịruru (ọkwa nke kansa), ihe ọ ga-arụpụta nwere ike igosi etu ọrịa kansa dị n’ahụ gị nakwa ma ọ nwere ike ịgbasa.

Ọ bụrụ na ejiri B2M nwalee ka ọgwụgwọ gị si arụ ọrụ nke ọma, nsonaazụ gị nwere ike igosi:

  • Ọkwa B2M gị na-aba ụba. Nke a nwere ike ịpụta na kansa gị na-agbasa, yana / ma ọ bụ ọgwụgwọ gị anaghị arụ ọrụ.
  • Ogo B2M gị na-ebelata. Nke a nwere ike ịpụta na ọgwụgwọ gị na-arụ ọrụ.
  • Ogwe B2M gị arịbeghị elu ma ọ bụ belata. Nke a nwere ike ịpụta na ọrịa gị kwụsie ike.
  • Ọkwa B2M gị belatara, mana emesịa ịbawanye. Nke a nwere ike ịpụta na ọrịa kansa gị alọghachila mgbe a gwọchara gị.

Ọ bụrụ na ị nwere ajụjụ gbasara nsonaazụ gị, gwa ndị ọrụ ahụike gị okwu.

Mụtakwuo maka ule nyocha ụlọ, akara ngosi, na nghọta nsonaazụ.

Enwere ihe ọ bụla ọzọ m kwesịrị ịma gbasara nnwale akara beta-2 microglobulin?

Beta-2 microglobulin na-anaghi eji ya eme ihe dika ihe nlere nke etuto maka ndi oria cancer. Mgbe ụfọdụ, a na-atụle ọkwa B2M ka:

  • Lelee mmebi akụrụ na ndị nwere ọrịa akụrụ.
  • Chọpụta ma nje nje, dịka nje HIV / AIDS, emetụtala ụbụrụ na / ma ọ bụ ọkpụkpụ azụ.
  • Lelee ma ọ bụrụ na ọrịa agafeela na ndị nwere ọrịa akwara, ọrịa na-adịghị ala ala nke na-emetụta ụbụrụ na ụbụrụ.

Ntughari

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  3. American Cancer Society [Intanet]. Atlanta: American Cancer Society Inc.; c2018. Otutu Myeloma Stages; [emelitere 2018 Feb 28; akpọrọ 2018 Jul 28]; [ihe dị ka ihuenyo 5]. O nwere site na: https://www.cancer.org/cancer/multiple-myeloma/detection-diagnosis-staging/staging.html
  4. Bagnoto F, Durastanti V, Finamore L, Volante G, Millefiorini E. Beta-2 microglobulin na neopterin dị ka ihe nrịbama nke ọrịa na otutu sclerosis. Neurol Sci [Intanet]. 2003 Dec [zoro aka na 2018 Jul 28] ;; 24 (5): s301-s304. Nweta ya site na: https://link.springer.com/article/10.1007%2Fs10072-003-0180-5
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Ejila ozi dị na saịtị a dị ka onye dochie anya nlekọta ahụike ọkachamara ma ọ bụ ndụmọdụ. Kpọtụrụ onye na-ahụ maka ahụike ma ọ bụrụ na ị nwere ajụjụ gbasara ahụike gị.

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