Niacinamide

Ndinaya

• Ikekwe ọ dị irè maka ...
• Ekwe omume irè n'ihi na ...
• Ikekwe adighi ike maka ...
• Ezughi oke akaebe iji gosipụta irè maka ...
• Akpachapụ anya na ịdọ aka na ntị:

E nwere ụdị vitamin B3 abụọ. Otu ụdị bụ niacin, nke ọzọ bụ niacinamide. A na-ahụ Niacinamide n'ọtụtụ nri gụnyere yist, anụ, azụ, mmiri ara ehi, akwa, akwụkwọ nri akwụkwọ ndụ akwụkwọ ndụ, agwa, na ọka ọka. A na - ahụ Niacinamide n'ọtụtụ mgbakwunye mgbakwunye vitamin B na vitamin B ndị ọzọ. Niacinamide nwekwara ike kpụrụ ke idem si nri niacin.

Emegharịla niacinamide na niacin, NADH, nicotinamide riboside, inositol nicotinate, ma ọ bụ tryptophan. Hụ ndepụta dị iche iche maka isiokwu ndị a.

A na-eji ọnụ Niacinamide eme ihe iji gbochie ụkọ vitamin B3 na ọnọdụ ndị metụtara ya dị ka pellagra. A na-ejikwa ya egburu ya maka otutu, ọrịa shuga, ọrịa cancer ọnụ, ọrịa ogbu na nkwonkwo, na ọtụtụ ọnọdụ ndị ọzọ. Agbanyeghị, enweghị ezigbo ihe akaebe sayensị iji kwado ojiji ndị a.

Niacinamide na-etinyere na akpụkpọ maka ihe otutu, eczema, na ndị ọzọ na anụ ọnọdụ. Enweghi ezigbo ihe akaebe iji kwado ojiji ndị a.

Natural Medicines Comprehensive database ọnụego na-arụ ọrụ dabere na ihe akaebe sayensị dịka usoro a si dị: Mmetụta, Ikekwe Ọ Ga-arụpụta Ihe, Ikekwe Ọ Ga-arụpụta Ihe, Ikekwe Ọ Dị Irè, Ikekwe Ọ Dị Irè, Adịghị Eme Ihe, na Ego ezughi ezu iji gosi.

Radị irè maka NIACINAMIDE ndị dị ka ndị a:

Ikekwe ọ dị irè maka ...

• Ọrịa nke ọrịa niacin (pellagra) kpatara. Niacinamide bụ U.S. Food and Drug Administration (FDA) kwadoro maka ojiji ndị a. A na-ahọrọ Niacinamide mgbe ụfọdụ karịa niacin n'ihi na ọ naghị akpata "ịchapu," (acha ọbara ọbara, itching na tingling), a mmetụta nke ọgwụgwọ niacin.

Ekwe omume irè n'ihi na ...

• Ihe otutu. Nnyocha mbụ emere na-egosi na ị tabletsụ mbadamba ihe nwere niacinamide na ihe ndị ọzọ maka izu 8 na-eme ka ọdịdị anụ ahụ dịkwuo mma na ndị nwere ihe otutu. Nnyocha ndị ọzọ na-egosi na itinye ude nwere niacinamide na-eme ka ọdịdị nke anụ ahụ dị na ndị nwere ihe otutu.
• Ọrịa shuga. Nnyocha ụfọdụ na-egosi na ị niụ niacinamide nwere ike inye aka igbochi ọnwụ nke insulin na ụmụaka na ndị okenye nọ n'ihe ize ndụ maka ụdị ọrịa shuga 1. O nwekwara ike igbochi mmebi nke insulin ma belata ọgwụ insulin chọrọ nke ụmụaka na-arịa ọrịa shuga nke ụdị 1 na nso nso a. Nanso, niacinamide no da so ara yɛ asiane a esisi wɔ mmirikatu bi a wɔfrɛ no type 1 mu no. N’ebe ndị mmadụ na-arịa ụdị ọrịa shuga nke abụọ, niacinamide yiri ka ọ na-enye aka igbochi mmepụta insulin ma melite njikwa shuga dị n’ọbara.
• Akwa phosphate n'ime ọbara (hyperphosphatemia). Nnukwu ọbara dị elu nke phosphate nwere ike ịbelata arụ ọrụ akụrụ. Na ndị mmadụ na akụrụ odida bụ ndị na hemodialysis na nwere elu-etoju nke ọbara phosphate, na-ewere niacinamide yiri ka na-enyere ibelata phosphate etoju mgbe e were ma ọ bụ na-enweghị phosphate binders.
• Isi na olu cancer. Nnyocha na-egosi na ị niụ niacinamide mgbe ọ na-anata ọgwụgwọ redio na ụdị ọgwụgwọ a na-akpọ carbogen nwere ike inyere aka ịchịkwa uto etuto na ịbawanye lanarị na ụfọdụ ndị nwere ọrịa akwara larynx. Niakingụ niacinamide mgbe ị na-anata ọgwụgwọ redio na carbogen yiri ka ọ na-erite uru nye ndị nwere ọrịa kansa nke nkọlọ ndị nwekwara ọbara ọgbụgba. O yikwara ka ọ na-enyere ndị nwere akpụ etufu ikuku oxygen aka.
• Ọrịa akpụkpọ anụ. Iwere niacinamide yiri ka ọ ga - enyere aka igbochi kansa ọhụụ ọhụrụ ma ọ bụ ntụpọ ndị pụtara ihe (actinic keratosis) ka ha ghara ito eto mmadụ nwere ọrịa kansa ma ọ bụ keratosis actinic.
• Ọrịa ogbu na nkwonkwo. Niakingụ niacinamide yiri ka ọ na-eme ka nkwonkwo dịkwuo mma ma belata ihe mgbu na ọzịza na ndị nwere ọrịa ogbu na nkwonkwo. Ọzọkwa, ụfọdụ ndị nwere ọrịa ogbu na nkwonkwo nke na-a niụ ọgwụ niacinamide nwere ike ọ dị mkpa ka ha were obere ọgwụ mgbu.

Ikekwe adighi ike maka ...

• Ọrịa ụbụrụ. Nnyocha e mere na mbụ gosiri na ịgwọ ndị nwere akpụ akpụ ụbụrụ wepụrụ site na niacinamide, radiotherapy, na carbogen adịghị eme ka ndụ dị mma ma e jiri ya tụnyere rediotherapy ma ọ bụ rediotherapy na carbogen.
• Ọrịa eriri afo. Gwọ ọrịa nwere eriri afọ na niacinamide, rediotherapy, na carbogen adịghị ibelata uto tumo ma ọ bụ melite lanarị ma e jiri ya tụnyere rediotherapy ma ọ bụ rediotherapy na carbogen.

Ezughi oke akaebe iji gosipụta irè maka ...

• Ọrịa anya nke na - eduga n'ịhụhụ ọhụụ na ndị okenye (nsogbu metụtara ọrịa afọ ma ọ bụ AMD). Nnyocha emere na mbụ na-egosi na ị niụ niacinamide, vitamin E na lutein n’otu afọ na-akawanye mma etu ọrụ retina si arụ ọrụ n’ebe ndị nwere ọhụụ ụzọ nọ n’ihi afọ na-akpata mmebi retina.
• Skinka nká. Nnyocha mbụ mere na-egosi na itinye ude nwere 5% niacinamide na ihu na-eme ka blotchiness, wrinkles, elasticity, na ọbara ọbara na-acha ọbara ọbara na ụmụ nwanyị nwere akpụkpọ ahụ merela agadi n'ihi mmebi anyanwụ.
• Eczema (atopic dermatitis). Nnyocha mbụ mere na-egosi na itinye ude nwere 2% niacinamide na-ebelata mmiri na-eme ka mmiri dịkwuo mma, na-ebelata ọbara ọbara na nchapu, na ndị nwere eczema.
• Ntị mpe-hyperactivity disorder (ADHD). Enwere ihe akaebe na-emegiderịta onwe ha banyere ịba uru nke niacinamide yana vitamin ndị ọzọ maka ọgwụgwọ ADHD.
• Skin redness kpatara mmerụ ma ọ bụ mgbakasị (erythema). Nnyocha e mere na mbụ gosiri na itinye ude nwere niacinamide na-ebelata ịcha ọbara ọbara, nkụ, na ọkọ ahụ nke ọgwụ isotretinoin.
• Ọrịa akụrụ ogologo oge (ọrịa akụrụ na-adịghị ala ala ma ọ bụ CKD). Nnyocha emere na mbụ gosiri na ị niụ ọgwụ niacinamide anaghị enyere aka belata ọnya na ndị nwere ọrịa akụrụ.
• Ọchịchịrị gbara ọchịchịrị na ihu (melasma). Nnyocha mbụ mere na-egosi na itinye moisturizer nwere 5% niacinamide ma ọ bụ 2% niacinamide na 2% tranexamic acid maka izu 4-8 na-enyere aka mee ka anụ ahụ dị nro na ndị mmadụ nwere akpụkpọ gbara ọchịchịrị.
• Ọrịa cancer nke na - amalite sel ọbara ọcha (na - abụghị Hodgkin lymphoma). Nnyocha mbụ emere na-egosi na ị niụ niacinamide dị ka akụkụ nke ọgwụgwọ na ọgwụ a na-akpọ vorinostat nwere ike inyere ndị nwere lymphoma aka ịbanye na mgbaghara.
• Ọnọdụ akpụkpọ anụ nke na-akpata nācha ọbara ọbara na ihu (rosacea). Nnyocha mbụ emere na-egosi na ị tabletsụ mbadamba ihe nwere niacinamide na ihe ndị ọzọ maka izu 8 na-eme ka ọdịdị anụ ahụ dịkwuo mma na ndị nwere rosacea.
• Ike ike, akpụkpọ anụ na akpụkpọ ahụ na ihu (seborrheic dermatitis). Nnyocha mbụ emere na-egosi na itinye ude nwere 4% niacinamide nwere ike belata ncha ọbara ọbara na ịkpụcha akpụkpọ anụ na ndị nwere seborrheic dermatitis.
• Mmanya na-egbu egbu.
• Ọrịa Alzheimer.
• Ọrịa ogbu na nkwonkwo.
• Icheta ikike icheta ihe na iche echiche nke na-erukwa mgbe mmadụ mere agadi.
• Nsogbu.
• Ọbara mgbali elu.
• Ọrịa mmegharị ahụ.
• Ọrịa Premenstrual (PMS).
• Ọnọdụ ndị ọzọ.

Achọrọ ihe akaebe ọzọ iji gosipụta niacinamide maka ojiji ndị a.

Niacinamide nwere ike site na niacin na ahu. A na-agbanwe Niacin na niacinamide mgbe a na-ewere ya karịa ihe anụ ahụ chọrọ. Niacinamide na-agbaze ngwa ngwa na mmiri ma na-etinye ya nke ọma mgbe ọnụ na-ewere ya.

Achọrọ Niacinamide maka ọrụ kwesịrị ekwesị nke abụba na shuga na ahụ na iji jigide mkpụrụ ndụ dị mma.

N'adịghị ka niacin, niacinamide enweghị mmetụta bara uru na abụba, ekwesịghịkwa iji ya maka ịgwọ oke cholesterol ma ọ bụ nnukwu abụba dị n'ọbara. Mgbe e were ya n'ọnụ: Niacinamide bu O yikarịrị ka ọ dị nchebe maka ọtụtụ ndị toro eto mgbe ewerere na ego akwadoro. N'adịghị ka niacin, niacinamide anaghị akpata nsị. Otú ọ dị, niacinamide nwere ike ịkpata obere mmetụta dịka iwe iwe, gas, dizziness, rash, itching, na nsogbu ndị ọzọ. Iji belata ihe ize ndụ nke mmetụta ndị a, ndị toro eto kwesịrị izere ị niụ ọgwụ niacinamide na ọgwụ karịrị 35 mg kwa ụbọchị.

Mgbe a na-ewere ihe karịrị gram 3 kwa ụbọchị nke niacinamide, mmetụta ndị ka njọ nwere ike ime. Ndị a gụnyere nsogbu imeju ma ọ bụ ọbara shuga dị elu.

Mgbe etinyere ya na akpụkpọ: Niacinamide bu Enwere ike nchekwa. Niacinamide ude nwere ike ime ka obere ọkụ, ọkọ, ma ọ bụ ọbara ọbara.

Akpachapụ anya na ịdọ aka na ntị:

Ime ime na ara-ara: Niacinamide bu O yikarịrị ka ọ dị nchebe maka ụmụ nwanyị dị ime na ndị na-enye ara ara mgbe ewere ego ole akwadoro. Ọnụ ọgụgụ kachasị nke niacin maka ụmụ nwanyị dị ime ma ọ bụ ndị na-enye ara ara bụ 30 mg kwa ụbọchị maka ụmụ nwanyị nọ n'okpuru afọ 18, na 35 mg kwa ụbọchị maka ụmụ nwanyị karịrị afọ 18.

Mụaka: Niacinamide bu O yikarịrị ka ọ dị nchebe mgbe a na-eji ọnụ na-atụ aro maka afọ ọ bụla. Mana ụmụaka kwesịrị izere ị niụ ọgwụ nke niacinamide karịa oke elu kwa ụbọchị, nke bụ 10 mg maka ụmụaka 1-3 afọ, 15 mg maka ụmụaka 4-8 afọ, 20 mg maka ụmụaka 9-13 afọ, yana 30 mg maka ụmụaka 14-18 afọ.

Ahụhụ: Niacinamide nwere ike ime ka nke ahụ dịkwuo njọ n'ihi na ha na-akpata histamine, kemịkalụ maka ihe nfụkasị ahụ, ka ewepụtara ya.

Ọrịa shuga: Niacinamide nwere ike ime ka ọbara shuga dịkwuo elu. Ndị mmadụ na-arịa ọrịa shuga na-a niụ niacinamide kwesịrị ịlele shuga shuga ha nke ọma.

Gallbladder ọrịa: Niacinamide nwere ike ime ka ọrịa gallbladder ka njọ.

Gout: Nnukwu ego nke niacinamide nwere ike ibute gout.

Ọrịa akụrụ: Akingakingụ niacinamide yiri ka ọ na-eme ka ihe ọghọm nke platelet dị ala na-abawanye na ndị nwere akụrụ akụrụ na-arịa ọrịa kansa.

Ọrịa imeju: Niacinamide nwere ike ime ka mmebi imeju. Ejila ya ma ọ bụrụ na ị nwere ọrịa imeju.

Afọ ma ọ bụ ọnya afọ: Niacinamide nwere ike ime ka ọnya na-akawanye njọ. Ejila ya ma ọ bụrụ na ị nwere ọnya.

Gerywa ahụ: Niacinamide nwere ike igbochi njikwa shuga ọbara n'oge na mgbe ịwachara ahụ. Kwụsị ị niụ niacinamide dịkarịa ala izu 2 tupu ịwa ahụ.

Agafeghị oke

Kpachara anya na nchikota a.

Carbamazepine (Tegretol)

Ahụ gbajiri Carbamazepine (Tegretol). Enwere ụfọdụ nchegbu na niacinamide nwere ike ibelata etu ọsịsọ ahụ mmadụ na-akwada carbamazepine (Tegretol). Mana ezughị ezu ịmara iji mara ma nke a ọ dị mkpa.

Ọgwụ ndị nwere ike imerụ umeji (ọgwụ Hepatotoxic)

Niacinamide nwere ike imerụ imeju, ọkachasị mgbe ejiri ya na nnukwu ọgwụ. Niakingụ niacinamide yana ọgwụ nke nwekwara ike imerụ imeju nwere ike ime ka ọnya imeju bawanye. Ejila ọgwụ niacinamide ma ọ bụrụ na ị na-a aụ ọgwụ nwere ike imerụ imeju.

Fọdụ ọgwụ nwere ike imerụ imeju gụnyere acetaminophen (Tylenol na ndị ọzọ), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporano) erythromycin (Erythrocin, Ilosone, ndị ọzọ), phenytoin (Dilantin), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), na ọtụtụ ndị ọzọ.

Ọgwụ nke na - eme ka mkpụkọ ọbara (Anticoagulant / Antiplatelet)

Niacinamide nwere ike belata mkpụkọ ọbara. Niakingụ niacinamide yana ọgwụ ndị na-eme ngwa ngwa na mkpụkọ mkpụkọ nwere ike ime ka ọnya na ọbara ọgbụgba nwee ike.

Somefọdụ ọgwụ na-eme ka mkpụkọ ọbara na-egbu oge gụnyere aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), na ndị ọzọ.

Primidone (Mysoline)

Primidone (Mysoline) gbajiri n’ahụ. Enwere ụfọdụ nchegbu na niacinamide nwere ike ibelata ọsọ ọsọ ahụ na-agbada primidone (Mysoline). Mana ezughị ezu ịmara iji mara ma nke a ọ dị mkpa.

Nkpuru ahihia na mmeju nke puru imebi umeji

Niacinamide nwere ike ịkpata mmebi imeju, ọkachasị mgbe ejiri ya na ogo dị elu. Niakingụ niacinamide yana ahịhịa ndị ọzọ ma ọ bụ mgbakwunye nwere ike imerụ imeju nwere ike ime ka ihe egwu a dịrịkwuo. Fọdụ n'ime ngwaahịa ndị a gụnyere androstenedione, borage leaf, chaparral, comfrey, dehydroepiandrosterone (DHEA), germander, kava, pennyroyal oil, red yist, na ndị ọzọ.

Mkpụrụ akwụkwọ na ọgwụ nwere ike belata mkpụkọ ọbara

Niacinamide nwere ike belata mkpụkọ ọbara. Iji niacinamide na ahihia ndi ozo na ihe ndi ozo nke na egbochi mkpụkọ ọbara nwere ike ime ka ohere igba obara na ufodu ndi mmadu. Herbsfọdụ ahihia ndị ọzọ dị n'ụdị a gụnyere Angelica, clove, danshen, galik, ginger, Panax ginseng, na ndị ọzọ.

Enweghi mmekorita ya na ihe oriri.

A na-amụ usoro ndị a na nyocha sayensị:

NDUL okenye

Site n'ọnụ:

• General: Somefọdụ ngwaahịa mgbakwunye anaghị enwe ike depụta niacinamide iche na aha ahụ. Kama, enwere ike depụta ya n'okpuru niacin. A na-eji Niacin atụnye ọnụ (Ni). Otu ọgwụ nke 1 mg nke niacinamide bụ otu ihe dị ka 1 mg NE. Nkwụnye nri maka nri ụbọchị (RDAs) kwa ụbọchị maka niacinamide na ndị okenye bụ 16 mg NE maka ụmụ nwoke, 14 mg NE maka ụmụ nwanyị, 18 mg NE maka ụmụ nwanyị dị ime, yana 17 mg NE maka ụmụ nwanyị na-enye ara ara.
• Maka ihe otutu: Mbadamba nwere 750 mg nke niacinamide, 25 mg zinc, 1.5 mg nke ọla kọpa, na 500 mcg nke folic acid (Nicomide) otu ugboro ma ọ bụ ugboro abụọ na-eji. Ọzọkwa, a na-ewere mbadamba 1-4 nke nwere niacinamide, azelaic acid, zinc, vitamin B6, ọla kọpa, na folic acid (NicAzel, Elorac Inc., Vernon Hills, IL) kwa ụbọchị.
• Maka vitamin B3 erughi mgbaàmà ndị dị ka pellagra: 300-500 mg kwa ụbọchị nke niacinamide na-enye na usoro nkewa.
• Maka ọrịa shuga: Niacinamide 1.2 gram / m² (ahụ dị n'elu) ma ọ bụ 25-50 mg / kg na-eji ụbọchị ọ bụla iji belata ọganihu nke ụdị ọrịa shuga 1. Ọzọkwa, a na-eji 0,5 gram nke niacinamide ugboro atọ kwa ụbọchị iji belata nrịanrịa nke ụdị ọrịa shuga 2.
• Maka ọkwa dị elu nke phosphate n'ime ọbara (hyperphosphatemia): Niacinamide site na 500 mg ruo 1.75 grams kwa ụbọchị na nkewa kewara maka 8-12 izu.
• Maka ọrịa kansa nke nkọlọ: 60 mg / kg nke niacinamide ka enyere 1-1.5 awa tupu ikuba carbogen (2% carbon dioxide na 98% oxygen) tupu na n’oge rediotherapy.
• Maka ọrịa anụ ahụ na-abụghị melanoma: 500 mg nke niacinamide otu ugboro ma ọ bụ ugboro abụọ kwa ụbọchị maka ọnwa 4-12.
• Maka ịgwọ ọrịa ogbu na nkwonkwo: Gram atọ nke niacinamide kwa ụbọchị na usoro dị iche iche maka izu iri na abụọ.

N'elu akpụkpọ ahụ:

• Ihe otutu: Gel nwere 4% niacinamide ugboro abụọ kwa ụbọchị.

M .AKA

• General: (RDAs) a na-atụ aro maka nri nri kwa ụbọchị maka niacinamide na ụmụaka bụ 2 mg maka ụmụ ọhụrụ 0-6 ọnwa, 4 mg NE maka ụmụ ọhụrụ 7-12 ọnwa, 6 mg NE maka ụmụaka 1-3 afọ, 8 mg NE maka ụmụaka 4-8 afọ, 12 mg NE maka ụmụaka 9-13 afọ, 16 mg NE maka ụmụ nwoke 14-18, na 14 mg NE maka ụmụ nwanyị 14-18 afọ.
• Maka ihe otutu: N'ime ụmụaka ọ dịkarịa ala afọ 12, a na-ewere mbadamba 1-4 nke nwere niacinamide, azelaic acid, zinc, vitamin B6, ọla kọpa, na folic acid (NicAzel, Elorac Inc., Vernon Hills, IL) kwa ụbọchị.
• Maka pellagra: 100-300 mg nke niacinamide na-enye kwa ụbọchị na nkewa kewara.
• Maka ụdị ọrịa shuga nke 1: 1,2 gram / m² (anụ ahụ dị n'elu) ma ọ bụ 25-50 mg / kg nke niacinamide na-eji kwa ụbọchị iji mee ka ọ ghara ịmalite ma ọ bụ gbochie ụdị ọrịa shuga 1.

3-Pyridine Carboxamide, 3-Pyridinecarboxamide, Amide de l'Acide Nicotinique, B Complex Vitamin, Complex de Vitamines B, Niacinamida, Nicamid, Nicosedine, Nicotinamide, Nicotinic Acid Amide, Nicotylamidum, Pyridine-3-carboxamide, Vitamin B3, Vitamina B , Vitamine B3.

Iji mụtakwuo banyere otú e si dee isiokwu a, biko lee Natural Medicines Comprehensive database usoro.

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Nyochaa ikpeazụ - 10/05/2020