CPK isoenzymes ule

Ihe okike phosphokinase (CPK) isoenzymes nyocha dị iche iche nke CPK n'ime ọbara. CPK bu enzyme nke achoputara karie n’obi, ụbụrụ na akwara.

Achọrọ nlebara ọbara. Enwere ike iwere nke a site na akwara. Ule a ka ana-akpọ venipuncture.

Ọ bụrụ n ’ụlọ ọgwụ, a ga-eme ule a karịa ụbọchị abụọ ma ọ bụ atọ. Nnukwu ịrị elu ma ọ bụ ọdịda na ngụkọta CPK ma ọ bụ CPK isoenzymes nwere ike inyere onye na-ahụ maka ahụike gị aka ịchọpụta ọnọdụ ụfọdụ.

Enweghị ịkwadebe pụrụ iche n'ọtụtụ ọnọdụ.

Gwa onye na-enye gị ọgwụ niile ị na-a .ụ. Drugsfọdụ ọgwụ nwere ike igbochi nsonaazụ nyocha. Ọgwụ nke nwere ike ịbawanye nha CPK gụnyere ihe ndị a:

• Mmanya na-aba n'anya
• Amphotericin B
• Anfọdụ ọgwụ anaestetị
• Cocaine
• Ọgwụ ọjọọ
• Statins
• Steroid, dịka dexamethasone

Ndepụta a abụghị ihe niile.

Nwere ike ịnwe obere ihe mgbu mgbe etinyere agịga iji see ọbara. Peoplefọdụ ndị na-enwe mmetụta nanị ahịhịa ma ọ bụ ihe na-agba agba. Mgbe nke ahụ gasịrị, enwere ike ịpị ụfọdụ mmiri.

Emere ule a ma oburu na ule CPK gosiputara na onu ogugu CPK gi di elu. Nyocha CPK isoenzyme nwere ike inyere aka chọta ezigbo isi iyi nke anụ ahụ mebiri emebi.

CPK nwere ihe atọ dị iche iche dị iche iche:

• A na - ahụkarị CPK-1 (nke a na-akpọkwa CPK-BB) ụbụrụ na ngụgụ
• CPK-2 (akpọkwara CPK-MB) dịkarịsịrị obi
• CPK-3 (nke a na-akpọkwa CPK-MM) bụ nke a na-ahụkarị n’ọkpụkpụ akwara

Ọkwa dị elu karịa CPK-1 nkịtị:

N'ihi na a na - ahụkarị CPK-1 n'ụbụrụ na ngụgụ, mmerụ ahụ na nke ọ bụla n'ime ebe ndị a nwere ike ịbawanye ọkwa CPK-1. Levelsbawanye CPK-1 ọkwa nwere ike ịbụ n'ihi:

• Ọrịa ụbụrụ
• Ọrịa ụbụrụ (n'ihi ụdị mmerụ ọ bụla gụnyere, ọrịa strok, ma ọ bụ ọbara ọgbụgba na ụbụrụ)
• Electroconvulsive ọgwụ
• Akpa ume infarction
• Ọdịdọ

Ọkwa dị elu karịa CPK-2 nkịtị:

Ọnọdụ CPK-2 na-ebili awa 3 ruo 6 mgbe nkụchi obi gasịrị. Ọ bụrụ na enweghi mmerụ ahụ obi ọzọ, ọkwa ahụ na-elu na 12 ruo 24 awa wee laghachi na 12 ruo 48 awa nkịtị mgbe anụ ahụ nwụsịrị.

Ubara CPK-2 etoju nwekwara ike ịbụ n'ihi na:

• Ọrịa eletrik
• Obi defibrillation (ebumnuche na-awụ akpata oyi n'ahụ nke ndị ọrụ ahụike)
• Mmetụta obi (dịka ọmụmaatụ, site na mberede ụgbọ ala)
• Mbufụt nke akwara obi na-abụkarị n'ihi nje (myocarditis)
• Mepee ịwa ahụ obi

CPdị CPK-3 dị elu karịa nke nkịtị na-abụkarị ihe ịrịba ama nke mmerụ ahụ ike ma ọ bụ nrụgide ahụ ike. Ha nwere ike ịbụ n'ihi:

• Azọpịa mmerụ ahụ
• Mbibi akwara n'ihi ọgwụ ọjọọ ma ọ bụ ịbụ onye na-enweghị ike ije ogologo oge (rhabdomyolysis)
• Ọrịa dystrophy
• Myositis (akwara ọkpụkpụ mbufụt)
• Nata ọtụtụ injections intramuscular
• Nyocha akwara na akwara na-adịbeghị anya (electromyography)
• N'oge na-adịghị anya
• Surgerywa ahụ n'oge na-adịbeghị anya
• Mmega ahụ siri ike

Ihe ndị nwere ike imetụta nsonaazụ nnabata gụnyere catheterization obi, intramuscular injections, ịwa ahụ n'oge na-adịbeghị anya, na mmega ahụ siri ike na ogologo oge ma ọ bụ ịkwagharị.

Nnyocha Isoenzyme maka ọnọdụ ụfọdụ gbasara 90% ziri ezi.

Creatine phosphokinase - isoenzymes; Creatine kinase - isoenzymes; CK - isoenzymes; Mwakpo obi - CPK; Crush - CPK

• Nnwale ọbara

Anderson JL. Nkebi nke St St elu elu myocardial infarction na nsogbu nke myocardial infarction. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke iri abụọ na ise. Philadelphia, PA: Elsevier Saunders; 2016: isi 73.

Marshall WJ, Day A, Lapsley M. Plasma protein na enzymes. Na: Marshall WJ, Day A, Lapsley M, eds. Ọgwụ Clinical. 8th ed. Philadelphia, PA: Elsevier; 2017: isi 16.

Nagaraju K, Gladue HS, Lundberg IE. Ọrịa inflammatory nke akwara na myopathies ndị ọzọ. Na: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Akwụkwọ Kelley na Firestein nke Rheumatology. Nke iri. Philadelphia, PA: Elsevier Saunders; 2017: isi 85.

Selcen D. Ọrịa akwara. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke iri abụọ na ise. Philadelphia, PA: Elsevier Saunders; 2016: isi 421.