Creatine phosphokinase ule

Creatine phosphokinase (CPK) bụ enzyme n’ahụ. A na-ahụkarị ya na obi, ụbụrụ, na akwara ọkpụkpụ. Isiokwu a tụlere ule iji tụọ ego nke CPK n'ime ọbara.

Achọrọ nlebara ọbara. Enwere ike iwere nke a site na akwara. A na-akpọ usoro ahụ venipuncture.

Enwere ike ịmegharị ule a karịa ụbọchị 2 ma ọ bụ 3 ma ọ bụrụ na ị bụ onye ọrịa na ụlọ ọgwụ.

Ọ dịghị nkwadebe pụrụ iche achọrọ ọtụtụ oge.

Gwa onye na-ahụ maka ahụike gị banyere ọgwụ ọ bụla ị na-a .ụ. Ọgwụ nke nwere ike ịbawanye nha CPK gụnyere amphotericin B, ụfọdụ ọgwụ anaesthetics, statins, fibrates, dexamethasone, mmanya na cocaine.

Nwere ike ịnwe obere ihe mgbu mgbe etinyere agịga iji see ọbara. Peoplefọdụ ndị na-enwe mmetụta nanị ahịhịa ma ọ bụ ihe na-agba agba. Mgbe nke ahụ gasịrị, enwere ike ịpị ụfọdụ mmiri.

Mgbe ngụkọta CPK zuru oke dị elu, ọ na-apụtakarị na enwere mmerụ ahụ ma ọ bụ nrụgide na anụ ahụ, obi, ma ọ bụ ụbụrụ.

Ọkpụkpụ anụ ahụ akwara na-adịkarị. Mgbe akwara mebiri, CPK na-abanye n'ọbara. Chọta ụdị ụdị CPK dị elu na-enyere aka ịchọpụta ụdị anụ ahụ mebiri emebi.

Ule a nwere ike iji:

• Chọpụta ọrịa obi
• Nyochaa ihe kpatara obi mgbu
• Kpebisie ike ma ọ bụ ma ọ bụ otú oke akwara mebiri emebi
• Chọpụta dermatomyositis, polymyositis, na ọrịa ndị ọzọ na-akpata akwara
• Gwa ihe dị iche n’etiti ajọ hyperthermia na ọrịa na-esochi ọrịa

Patternkpụrụ na oge ịrị elu ma ọ bụ ọdịda na ọkwa CPK nwere ike ịdị ịrịba ama n'ịchọpụta nchoputa. Nke a bụ eziokwu karịsịa ma ọ bụrụ na a na-enyo enyo obi nkụchi.

N'ọtụtụ oge, a na-eji nyocha ndị ọzọ eji eme ihe ma ọ bụ jiri ule a iji chọpụta ọnya obi.

Total CPK nkịtị ụkpụrụ:

• 10 ka 120 microgram kwa liter (mcg / L)

Usoro ntanetị dị iche iche nwere ike ịdịtụ iche n'etiti ụlọ nyocha dị iche iche. Lafọdụ labs na-eji nha dị iche iche ma ọ bụ nwalee ụdị dị iche iche. Gwa onye na - enye gị ọrụ gbasara ihe nyocha gị pụtara.

Enwere ike ịhụ ọkwa CPK dị elu na ndị mmadụ nwere:

• Mbibi ụbụrụ ma ọ bụ ọrịa strok
• Ọgba aghara
• Delirium tremens
• Dermatomyositis ma ọ bụ polymyositis
• Ujo eletrik
• Obi nkolopu
• Mbufụt nke akwara obi (myocarditis)
• Ugbo anụ ahụ ọnwụ (akpa ume infarction)
• Ọkpụkpụ dystrophies
• Myopathy
• Rhabdomyolysis

Ọnọdụ ndị ọzọ nwere ike inye nsonaazụ nnwale dị mma gụnyere:

• Hypothyroidism na-agwọ ọrịa
• Hyperthyroidism
• Pericarditis na-eso nkụchi obi

Ihe ize ndụ metụtara na ịmịnye ọbara dị ntakịrị mana ọ nwere ike ịgụnye:

• Ọbara ọgbụgba
• Da mba ma ọ bụ inwe isi ọkụ
• Hematoma (ọbara na-agbakọta n'okpuru anụ ahụ)
• Ofufe Ọrịa (ntakịrị ihe egwu oge ọ bụla anụ ahụ agbajiri)

Ekwesịrị ime nyocha ndị ọzọ iji chọta kpọmkwem ọnọdụ nke mmebi ahụ ike.

Ihe ndị nwere ike imetụta nsonaazụ nyocha gụnyere catheterization obi, intramuscular injections, trauma na akwara, ịwa ahụ n'oge na-adịbeghị anya, na mmega ahụ siri ike.

Nyocha CPK

• Nnwale ọbara

Anderson JL. Nkebi nke St St elu elu myocardial infarction na nsogbu nke myocardial infarction. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke iri abụọ na ise. Philadelphia, PA: Elsevier Saunders; 2016: isi 73.

Carty RP, Pincus MR, Sarafraz-Yazdi E. Clinical enzymology. Na: McPherson RA, Pincus MR, eds. Henry’s Clinical Diagnosis and Management site na Labozọ Laboratory. 23 nke ed. Philadelphia, PA: Elsevier; 2017: isi 20.

Mccullough PA. Nkọwa n'etiti ọrịa akụrụ na ọrịa obi. Na: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Ọrịa Obi Braunwald: Akwụkwọ ọgụgụ nke Ọgwụ Ọrịa Cardiovascular. Nke 11. Philadelphia, PA: Elsevier; 2019: isi 98.

Nagaraju K, Gladue HS, Lundberg IE. Ọrịa inflammatory nke akwara na myopathies ndị ọzọ. Na: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Akwụkwọ Kelley na Firestein nke Rheumatology. Nke iri. Philadelphia, PA: Elsevier Saunders; 2017: isi 85.