17-hydroxycorticosteroids mmamịrị ule

Ihe nyocha 17-hydroxycorticosteroids (17-OHCS) na-atụle ogo 17-OHCS na mamịrị.

A chọrọ mamịrị nke 24 awa. Ikwesiri ịnakọta mamịrị gị karịa awa 24. Ndị na-ahụ maka ahụike ga-agwa gị otu esi eme nke a. Soro ntuziaka.

Ndị na-eweta ọrụ ahụ ga - agwa gị, ọ bụrụ na ọ dị mkpa, ịkwụsị ọgwụ ndị nwere ike igbochi ule ahụ. Ndị a nwere ike ịgụnye:

• Mkpụrụ ọgwụ na-amụ nwa nke nwere estrogen
• Antibioticsfọdụ ọgwụ nje
• Glucocorticoids

Nnwale ahụ gụnyere urination nkịtị. Enweghị nkasi obi.

17-OHCS bụ ngwaahịa etolite mgbe umeji na anụ ahụ ndị ọzọ na-akwada cortisol hormone steroid.

Nnwale a nwere ike inyere aka chọpụta ma ahụ ọ na-emepụta cortisol buru oke ibu. Enwere ike iji ule ahụ chọpụta ọrịa Cushing. Nke a bụ nsogbu na - eme mgbe ahụ nwere ogo cortisol dị elu mgbe niile.

A na-ejikarị mmamịrị na mmamịrị creatinine mee nyocha 17-OHCS n'otu oge ahụ. Nke a na-enyere onye na-eweta ọrụ aka ịkọwa ule ahụ.

Ule a anaghị eme oge ugbu a. Nnwale mmamịrị cortisol n'efu bụ ule nyocha ka mma maka ọrịa Cushing.

Valueskpụrụ nkịtị:

• Nwoke: 3 ka 9 mg / 24 awa (8.3 ka 25 olmol / 24 awa)
• Nwanyi: 2 ka 8 mg / 24 awa (5.5 ka 22 olmol / 24 awa)

Usoro ntanetị dị iche iche nwere ike ịdịtụ iche n'etiti ụlọ nyocha dị iche iche. Lafọdụ labs na-eji nha dị iche iche ma ọ bụ nwalee ụdị dị iche iche. Gwa onye na - enye gị ọrụ gbasara ihe nyocha gị pụtara.

Ọkwa dị elu karịa nke 17-OHCS nwere ike igosi:

• Dị ọrịa Cushing nke akpụ site na akpụ na adrenal gland na-emepụta cortisol
• Nsogbu
• Hydrocortisone ọgwụ
• Erighị nri na-edozi ahụ
• Ibu
• Ime afọ ime
• Ihe hormonal na-akpata oke ọbara mgbali elu
• Oké nrụgide anụ ahụ ma ọ bụ nke mmetụta uche
• Tumor na pituitary gland ma ọ bụ ebe ọzọ n'ime ahụ na-ewepụta homonụ a na - akpọ homonụ adrenocorticotropic (ACTH)

Usoro dị ala karịa nke nkịtị nke 17-OHCS nwere ike igosi:

• Adrenal glands anaghị amịpụta oke nke homonụ ha
• Pituitary gland anaghị arụpụta oke nke homonụ ya
• Erughị enzyme e ketara eketa
• Surgerywa ahụ gara aga iji wepu adrenal gland

Rinrinụ ihe karịrị lita 3 kwa ụbọchị (polyuria) nwere ike ime ka nsonaazụ ule ahụ dị elu n'agbanyeghị na mmepụta cortisol bụ ihe nkịtị.

Enweghị nsogbu dị na ule a.

17-OH corticosteroids; 17-OHCS

Chernecky CC, Berger BJ. 17-hydroxycorticosteroids (17-OHCS) - 24 awa mmamịrị. Na: Chernecky CC, Berger BJ, eds. Nnwale Laboratory na Usoro Nyocha. Nke isii. St Louis, MO: Elsevier Saunders; 2013: 659-660.

Juszczak A, Morris DG, Grossman AB, Nieman LK. Ọrịa Cushing. Na: Jameson JL, De Groot LJ, de Kretser DM, et al, ndị ọzọ. Endocrinology: Okenye na Ọrịa edimụaka. Nke 7. Philadelphia, PA: Elsevier Saunders; 2016: isi 13.