TBG ule ọbara

Nnwale ọbara TBG na-atụle ogo nke protein nke na-akpali hormone thyroid n'ahụ gị dum. A na-akpọ protein a thyroxine binding globulin (TBG).

A na-ewere ihe nlele ọbara wee zigara ya na laabu maka ule.

Drugsfọdụ ọgwụ na ọgwụ nwere ike imetụta nsonaazụ nnwale. Ndị na-ahụ maka ahụike gị nwere ike ịgwa gị ka ị kwụsị ị takingụ ọgwụ ụfọdụ obere oge tupu ule ahụ. Akwụsịla ị takingụ ọgwụ ọ bụla n’ebughị ụzọ gwa onye na-eweta ọrụ gị okwu.

Ọgwụ ndị a na ọgwụ ike nwere ike ịbawanye ọkwa TBG:

• Estrogens, a hụrụ na ọgwụ mgbochi ọmụmụ na ọgwụgwọ nnọchi estrogen
• Heroin
• Methadone
• Phenothiazines (ụfọdụ ọgwụ antipsychotic)

Ọgwụ ndị a nwere ike ibelata ọkwa TBG:

• Depakote ma ọ bụ depakene (a na-akpọkwa valproic acid)
• Dilantin (nke a na-akpọkwa phenytoin)
• Nnukwu salicylates, gụnyere aspirin
• Hormonesmụ nwoke na homonụ, gụnyere androgens na testosterone
• Prednisone

Mgbe etinyere agịga ahụ iji see ọbara, ụfọdụ ndị na-enwe oke mgbu. Ndị ọzọ na-eche nanị ịpị ma ọ bụ gbaa. Mgbe nke ahụ gasịrị, enwere ike ịpị ụfọdụ ụtarị ma ọ bụ ọnyá ntakịrị. Nke a ga - apụ n'anya.

Enwere ike ime ule a iji chọpụta nsogbu na thyroid gị.

Nkịtị dị bụ microgram 13 ruo 39 na deciliter (mcg / dL), ma ọ bụ 150 ruo 360 nanomoles kwa lita (nmol / L).

Usoro ntanetị dị iche iche nwere ike ịdịtụ iche n'etiti ụlọ nyocha dị iche iche. Lafọdụ labs na-eji nha dị iche iche ma ọ bụ nwee ike nwalee ụdị dị iche iche. Gwa onye na - enye gị ọrụ gbasara ihe nyocha gị pụtara.

Nrịgo elu TBG nwere ike ịbụ n'ihi:

• Nnukwu nkwụsịtụ porphyria (ọrịa na-emetụta ụbụrụ)
• Hypothyroidism (adịghị arụ ọrụ thyroid)
• Ọrịa imeju
• Ime ime (ọkwa TBG na-arịwanye elu n'oge ime ime)

Mara: TBG ọkwa dị elu n’ebe ụmụ amụrụ nọ.

Mbelata nke ogo TBG nwere ike ịbụ n'ihi:

• Nnukwu ọrịa
• Acromegaly (nsogbu nke oke hormone na-eto eto)
• Hyperthyroidism (thyroid arụ ọrụ)
• Erighị nri na-edozi ahụ
• Ọrịa Nephrotic (mgbaàmà na-egosi mmebi akụrụ bụ)
• Nchegbu site na ịwa ahụ

Ugo elu TBG dị elu ma ọ bụ dị ala na-emetụta mmekọrịta dị n'etiti nyocha T4 zuru oke na nnwale ọbara T4 n'efu. Ngbanwe nke ọkwa TBG nwere ike ịgbanwe ọgwụ kwesịrị ekwesị nke mgbanwe levothyroxine maka ndị nwere hypothyroidism.

E nwere obere ihe ize ndụ gụnyere ịnara ọbara gị. Akwara na akwara na-adịgasị iche site na otu onye gaa na onye ọzọ na site n'otu akụkụ nke ahụ gaa na nke ọzọ. Samplenata ọbara ọbara nke ụfọdụ ndị mmadụ nwere ike isi ike karịa n'aka ndị ọzọ.

Ihe ize ndụ ndị ọzọ nke ịnwe ọbara adịghị obere, mana ọ nwere ike ịgụnye:

• Ọbara ọgbụgba
• Da mba ma ọ bụ inwe isi ọkụ
• Otutu punctures chọta veins
• Hematoma (ọbara ọbara n'okpuru akpụkpọ)
• Ofufe Ọrịa (ntakịrị ihe egwu oge ọ bụla anụ ahụ agbajiri)

Ọbara thyroxine nkịtị globulin; TBG ọkwa; Ọbara TBG larịị; Hypothyroidism - TBG; Hyperthyroidism - TBG; Underactive thyroid - TBG; Oroid na-arụ ọrụ - TBG

• Nnwale ọbara

Guber HA, Farag AF. Nyocha nke ọrụ endocrine. Na: McPherson RA, Pincus MR, eds. Henry’s Clinical Diagnosis and Management site na Labozọ Laboratory. 23 nke ed. St Louis, MO: Elsevier; 2017: isi 24.

Kruse JA. Nsogbu thyroid gị. Na: Parrillo JE, Dellinger RP, eds. Ọgwụ Nlekọta Ahụ Ike: ofkpụrụ nke Nyocha na Nchịkwa na Okenye. Nke 5. Philadelphia, PA: Elsevier; 2019: isi 57.

Salvatore D, Cohen R, Kopp PA, Larsen PR. Thyroid pathophysiology na nyocha nyocha. Na: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Akwụkwọ ọgụgụ Williams nke Endocrinology. Nke iri na anọ. Philadelphia, PA: Elsevier; 2020: isi 11.