Ọrịa endometrium

Ọrịa endometrium bụ ọrịa kansa nke bidoro na endometrium, akwa nke akpanwa (akpa nwa).

Ọrịa endometrium bụ ụdị ọrịa cancer akpanwa na-ahụkarị. Amabeghị ihe kpatara ọrịa cancer endometrial. Ọganihu dị elu nke estrogen nwere ike ịrụ ọrụ. Nke a na - eme ka etolite nke akpanwa rụọ ọrụ. Nke a nwere ike iduga oke nha nke endometrium na kansa.

Imirikiti ọrịa cancer endometrial na-eme n’agbata afọ 60 na 70. Ọnọdụ ole na ole nwere ike ime tupu afọ 40.

Ihe ndị a metụtara homonụ gị na-abawanye ohere gị maka ọrịa kansa endometrial:

• Usoro ọgwụgwọ estrogen na-anọghị na progesterone
• Akụkọ banyere polyps endometrium
• Oge anaghị adịkarị
• Adịghị ime
• Ibu
• Ọrịa shuga
• Ọrịa polycystic ovary (PCOS)
• Menstrumalite ịhụ nsọ n'oge ị dị obere (tupu afọ iri na abụọ)
• Menbido nsọ nwanyị mgbe afọ 50 dị
• Tamoxifen, ọgwụ eji agwọ ara ure

Womenmụ nwanyị ndị nwere ọnọdụ ndị a yikarịrị ka ha nọ n'ọnọdụ dị elu karịa ọrịa kansa endometrial:

• Ọkpụkpụ afọ ma ọ bụ ọrịa ara ara
• Gallbladder ọrịa
• Ọbara mgbali elu

Mgbaàmà nke ọrịa cancer endometrial gụnyere:

• Ọbara na-adịghị ahụkebe sitere na ikpu, gụnyere ọbara ọgbụgba n'etiti oge ma ọ bụ ntụpọ / ọbara ọgbụgba mgbe menopause
• Oke ogologo, arọ, ma ọ bụ ugboro ugboro nke ọbara ọgbụgba mgbe afọ 40 gasịrị
• Ala mgbu ma ọ bụ mkpịsị pelvic

N'oge mmalite nke ọrịa, ule pelvic na-adịkarị mma.

• Na ọkwa dị elu, enwere ike inwe mgbanwe nha, ọdịdị, ma ọ bụ mmetụta nke akpanwa ma ọ bụ akụkụ ndị gbara ya gburugburu.
• Pap smear (nwere ike ibute enyo enyo maka ọrịa kansa endometrial, mana anaghị achọpụta ya)

Dabere na mgbaàmà gị na nchọpụta ndị ọzọ, enwere ike ịchọ nyocha ndị ọzọ. Enwere ike ịme ụfọdụ n'ime ụlọ ọrụ nlekọta ahụike gị. Enwere ike ịme ndị ọzọ n'ụlọ ọgwụ ma ọ bụ ebe a na-awa ahụ:

• Endometrial biopsy: Iji obere catheter ma ọ bụ dị mkpa (tube), a na-ewepụta anụ ahụ na akwa nke akpanwa (endometrium). A na-enyocha mkpụrụ ndụ ndị dị n'okpuru microscope iji hụ ma ọ̀ dị nke na-adịghị mma ma ọ bụ nke kansa.
• Hysteroscopy: A na-etinye ngwaọrụ dị ka teliskop dị mkpa site na ikpu na oghere nke cervix. Ọ na - ahapụ onye na - eweta ya ka ọ lelee n’ime akpanwa.
• Ultrasound: A na-eji ebili mmiri na-ada ụda na-eme ihe osise nke akụkụ ahụ pelvic. Enwere ike ịrụ ultrasound abdominally ma ọ bụ vaginally. Ultrasound nwere ike ikpebi ma ọ bụrụ na mkpuchi nke akpanwa na-egosi ọdịiche ma ọ bụ buru ibu.
• Sonohysterography: A na-etinye mmiri n'ime akpanwa site na tube dị mkpa, ebe a na-eji ihe omimi ultrasound na-emepụta nke akpanwa. Enwere ike ịme usoro a iji chọpụta ọnụnọ nke eriri afọ ọ bụla na-adịghị mma nke nwere ike ịbụ ihe na-egosi ọrịa kansa.
• Igwe ihe na-eme ka magnetik (MRI): Na ule nyocha a, a na-eji ihe ndị dị ike iji mepụta ihe oyiyi nke akụkụ ahụ.

Ọ bụrụ na achọpụtara kansa, enwere ike ịme nyocha iji chọpụta ma ọ bụrụ na kansa agbasawo n'akụkụ ndị ọzọ. A na-akpọ nke a staging.

Uzo nke orie endometrial bu:

• Nkeji nke 1: Ọrịa cancer bụ naanị n'ime akpanwa.
• Oge nke 2: Oria cancer di n’akpa nwa na cervix.
• Nkeji nke atọ: Ọrịa cancer agbasawo na mpụga nke akpanwa, mana ọ gafere akụkụ oke pelvis. Ọrịa nwere ike ịgụnye ọnya lymph na pelvis ma ọ bụ n'akụkụ aorta (nnukwu akwara na afọ).
• Oge nke 4: Ọrịa cancer agbasawo n'ime ime eriri afọ, eriri afọ, afọ, ma ọ bụ akụkụ ndị ọzọ.

A kọwakwara ọrịa kansa dị ka ọkwa nke 1, 2, ma ọ bụ 3. Gralọ akwụkwọ nke 1 dịkarịsịrị ike, na klaasị 3 kacha eme ihe ike. Ime ihe ike pụtara na ọrịa cancer na-eto ma na-agbasa ngwa ngwa.

Usoro ọgwụgwọ gụnyere:

• Gerywa ahụ
• Ọgwụ radieshon
• Ọgwụ

Enwere ike ịwa ahụ iji wepu akpanwa (hysterectomy) n'ime ụmụ nwanyị ndị nwere ọrịa 1 mbụ. Dọkịta ahụ nwekwara ike iwepu akpa na ovaries.

Gerywa ahụ tinyere ọgwụgwọ radieshon bụ nhọrọ ọgwụgwọ ọzọ. A na-ejikarị ya maka ụmụ nwanyị nwere:

• Nkeji 1 ọrịa nke nwere nnukwu ohere ịlaghachi, agbasaala na lymph, ma ọ bụ ọkwa 2 ma ọ bụ 3.
• Oge nke 2 ọrịa

A pụrụ ịtụle ọgwụ ọgwụ ma ọ bụ ọgwụgwọ hormonal na ụfọdụ, ọtụtụ mgbe maka ndị nwere ọrịa 3 na 4 ọrịa.

Nwere ike belata nchekasị nke ọrịa site na isonyere ndị otu na-akwado ọrịa kansa. Kọrọ ndị ọzọ ihe ha na-eme na nsogbu niile nwere ike inyere gị aka ichewe naanị gị.

Ọrịa endometrium na-ahụkarị na mmalite oge.

Ọ bụrụ na ọrịa kansa agbasaghị, 95% nke ụmụ nwanyị na-adị ndụ mgbe afọ 5 gachara. Ọ bụrụ na ọrịa kansa agbasawo na akụkụ ndị dị anya, ihe dịka 25% nke ụmụ nwanyị ka dị ndụ mgbe afọ 5 gachara.

Nsogbu nwere ike ịgụnye nke ọ bụla n'ime ihe ndị a:

• Anaemia n'ihi ọbara ọgbụgba (tupu nchoputa)
• Perforation (oghere) nke akpanwa, nke nwere ike ime n'oge D na C ma ọ bụ endometrial biopsy
• Nsogbu si ịwa ahụ, radieshon, na chemotherapy

Kpọọ nhọpụta na onye na-eweta gị ma ọ bụrụ na ịnwere nke ndị a:

• Ọbara ọ bụla ma ọ bụ ntụpọ ọ bụla nke na-apụta mgbe mmalite nke nsọ nwanyị
• Ọbara ọgbụgba ma ọ bụ ntụpọ mgbe mmekọrịta ma ọ bụ douching
• Ọbara ọgbụgba dị ogologo karịa ụbọchị asaa
• Oge ezumike oge na-eme ugboro abụọ kwa ọnwa
• Ọpụpụ ọhụụ mgbe emechara nwoke amalitela
• Pelvic mgbu ma ọ bụ cramping nke na-anaghị apụ apụ

Enweghị ule nyocha dị irè maka ọrịa cancer endometrial (uterine).

Womenmụ nwanyị ndị nwere nsogbu maka ọrịa cancer endometrial kwesịrị ịgbasochi anya na ndị dọkịta ha. Nke a gụnyere ụmụ nwanyị na-ewere:

• Usoro ọgwụgwọ estrogen na-enweghị ọgwụgwọ progesterone
• Tamoxifen maka ihe karịrị afọ 2

Enwere ike ịtụle ule pelvic ugboro ugboro, Pap smears, ultrasounds vaginal, na biopsy endometrial na ụfọdụ.

Ihe ize ndụ nke ọrịa cancer endometrial na-ebelata site na:

• Manọgide na-enwe nkịtị ibu
• Iji ọgwụ mgbochi ime ihe karịrị otu afọ

Endometrial adenocarcinoma; Akpịrị adenocarcinoma; Ọrịa cancer; Adenocarcinoma - endometrium; Adenocarcinoma - akpanwa; Ọrịa cancer - Eriri akpa nwa; Ọrịa cancer - endometrial; Uterine corpus cancer

• Hysterectomy - abdominal - ihapu
• Hysterectomy - laparoscopic - ihapu
• Hysterectomy - mmamiri - nhapu
• Pelvic radieshon - ihapu

• Pelvic laparoscopy
• Mmekpa ahụ nwa nwanyi
• D na C
• Endometrial biopsy
• Hysterectomy
• Akpankpu
• Ọrịa endometrium

Amaka DK. Ọrịa gynecologic. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke 26th. Philadelphia, PA: Elsevier; 2020: isi 189.

Boggess JF, Kilgore JE, Tran A-Q. Ọrịa Uterine. Na: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff’s Clinical Oncology. Nke isii. Philadelphia, PA: Elsevier; 2020: isi 85.

Morice P, Leary A, Creutzberg C, Abu-Rustum N, Darai E. Endometrial cancer. Lancet. 2016; 387 (10023): 1094-1108. PMID: 26354523 pubmed.ncbi.nlm.nih.gov/26354523/.

Weebụsaịtị National Cancer Institute. Endometrial cancer ọgwụgwọ (PDQ) -ike ọkachamara version. www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq. Emelitere December 17, 2019. Nabata March 24, 2020.

National Comprehensive Cancer Network weebụsaịtị. NCCN usoro nlekọta ahụike na oncology (NCCN ụkpụrụ nduzi): neoplasms uterine. 1.dị 1.2020. www.nccn.org/professionals/physician_gls/pdf/uterine.pdf. Emelitere March 6, 2020. Nabata March 24, 2020.