Ebumnuche VII erughị eru

Ihe kpatara Factor VII (asaa) bụ ọgba aghara nke enweghị protein a na-akpọ ihe nke VII n'ime ọbara. Ọ na - ebute nsogbu na nsị ọbara (coagulation).

Mgbe ị na-agba obara, usoro ihe na-eme n’ime ahụ nke na - enyere mkpụkọ ọbara aka. A na-akpọ usoro a coagulation cascade. Ọ gụnyere protein pụrụ iche a na-akpọ coagulation, ma ọ bụ ihe ndị na-eme ka ihe na-egbochi ọbara. May nwere ike ịnwe ohere dị elu nke ọbara ọgbụgba ma ọ bụrụ na otu ma ọ bụ karịa n'ime ihe ndị a na-efu ma ọ bụ na ha anaghị arụ ọrụ dịka ha kwesiri.

Ihe kpatara VII bụ otu ihe dị otú ahụ coagulation. Ihe kpatara VII na-erughị na ezinụlọ (ketara) ma dị oke ụkọ. Ndị nne na nna ga-enwerịrị mkpụrụ ndụ ihe nketa iji bufee ụmụ ha nsogbu a. Akụkọ ihe mere eme nke ezinụlọ banyere ọrịa ọgbụgba nwere ike ịbụ ihe egwu.

Ihe kpatara ụkọ VII nwekwara ike ịbụ n'ihi ọnọdụ ọzọ ma ọ bụ ojiji nke ụfọdụ ọgwụ. A na-akpọ nke a ihe kpatara VII erughi. Enwere ike kpatara ya:

• Vitamin K dị obere (a na-amụrụ ụfọdụ ụmụ vitamin vitamin)
• Ọrịa imeju siri ike
• Iji ọgwụ na-egbochi mkpụkọ (anticoagulants dị ka warfarin)

Mgbaàmà nwere ike ịgụnye nke ọ bụla n'ime ihe ndị a:

• Ọbara si na membranes
• Ọbara ọgbụgba na nkwonkwo
• Ọbara ọgbụgba n'ime akwara
• Bruising mfe
• Ọbara ọgbụgba n'oge ọbara ọbara
• Imi imi nke na-anaghị akwụsị ngwa ngwa
• Ọbara ọgbụgba mgbe amụrụ nwa

Ule nke enwere ike ime gunyere:

• Oge thromboplastin elekere (PTT)
• Ihe Plasma factor VII
• Oge Prothrombin (PT)
• Gwakọta ọmụmụ ihe, nyocha PTT pụrụ iche iji gosipụta ụkọ VII

Enwere ike ịchịkwa ọbara ọgbụgba site na inweta infravenous (IV) infusions nke plasma nkịtị, na-etinye uche nke ihe nke abụọ, ma ọ bụ na-emepụta mkpụrụ ndụ ihe nketa (recombinant) ihe nke VII.

Ga-achọ ọgwụgwọ ugboro ugboro n'oge ngosipụta ọbara ọgbụgba n'ihi na ihe nke VII anaghị adịte aka n'ime ahụ. A ga-ejikwa ụdị ihe nke VII akpọ NovoSeven.

Ọ bụrụ na ị nwere ụkọ VII n'ihi enweghị vitamin K, ị nwere ike were vitamin a site n'ọnụ, site na injections n'okpuru anụ ahụ, ma ọ bụ site na akwara (intravenously).

Ọ bụrụ na ị nwere ọrịa ọgbụgba a, hụ na:

• Gwa ndị na-elekọta ahụike gị tupu ịnwe ụdị usoro ọ bụla, gụnyere ịwa ahụ na ọrụ eze.
• Gwa ndị ezinụlọ gị maka na ha nwere ike otu ọrịa ahụ mana ha amabeghị ya.

Ihe ndị a nwere ike ịnyekwu ozi na ụkọ VII:

• National Hemophilia Foundation: Ihe ndị ọzọ kpatara - www.hemophilia.org/Bleeding-Disorders/Types-of-Bleeding-Disorders/Other-Factor-Deficiencies
• Organizationtù Mba Maka Ọrịa Na-adịghị - rarediseases.org/rare-diseases/factor-vii-deficiency
• NLM Nkọwa Homelọ Nkọwa - ghr.nlm.nih.gov/condition/factor-vii-deficiency

You nwere ike ịtụ anya nsonaazụ dị mma site na ọgwụgwọ kwesịrị ekwesị.

Ihe na-akpata ihe na-akpata VII bụ ụkọ ndụ.

Echiche maka ihe kpatara VII erughị eru dabere na ihe kpatara ya. Ọ bụrụ na ọ bụ ọrịa imeju kpatara ya, nsonaazụ ya dabere na otu esi agwọ ọrịa imeju gị. Vitaminnara mgbakwunye vitamin K ga-agwọ ụkọ vitamin K.

Nsogbu nwere ike ịgụnye:

• Oké ọbara ọgbụgba (ọbara ọgbụgba)
• Ọrịa strok ma ọ bụ nsogbu ndị ọzọ na-akpata ụjọ site na usoro ọbara ọbara nke etiti
• Nsogbu nkwonkwo n'okwu ndị siri ike mgbe ọbara ọgbụgba na-emekarị

Nweta ọgwụgwọ mberede ozugbo ọ bụrụ na ị nwere oke ọbara ọgbụgba na-enweghị atụ.

Enweghị mgbochi mgbochi mara maka ụkọ ihe kpatara VII. Mgbe enweghi vitamin K bụ ihe kpatara ya, iji vitamin K nwere ike inye aka.

Proconvertin erughi; Ihe ozo di iche; Ọbara prothrombin ntụgharị osooso erughi; Ọrịa Alexander

• Ọkpụkpụ ọbara
• Ọbara ọbara

Gailani D, Wheeler AP, Neff AT. Ọ bụ ụkọ coagulation kpatara erughị eru. Na: Hoffman R, Benz EJ, Silberstein LE, et al, ndị ọzọ. Hematology: ickpụrụ na Omume. Nke 7. Philadelphia, PA: Elsevier; 2018: isi 137.

JElọ Nzukọ JE. Hemostasis na coagulation ọbara. Na Hall JE, ed. Akwụkwọ Guyton na Halllọ Akwụkwọ Ahụike Ahụike. Nke 13. Philadelphia, PA: Elsevier; 2016: isi 37.

Ragni MV. Ọrịa ọgbụgba ọbara: ụkọ ihe kpatara nsogbu. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke iri abụọ na ise. Philadelphia, PA: Elsevier Saunders; 2016: isi 174.