Obere mgbanwe ọrịa

Obere mgbanwe ọrịa bụ ọrịa akụrụ nke nwere ike ibute ọrịa nephrotic. Ọrịa Nephrotic bụ otu mgbaàmà nke gụnyere protein na mmamịrị, ogo protein dị n'ọbara, ogo cholesterol dị elu, nnukwu triglyceride, na ọzịza.

Ihe mejupụtara akịrị nke ọ bụla n’ime ihe karịrị otu nde nkeji a na-akpọ nephron, nke na-aza ọbara ma na-emepụta mamịrị.

Na obere mgbanwe ọrịa, enwere mmebi nke glomeruli. Ndị a bụ obere arịa ọbara dị n'ime nephron ebe a na-edozi ọbara iji mee mmamịrị ma wepụ ihe mkpofu. Ọrịa ahụ na - enweta aha ya n'ihi na anaghị ahụ mmebi a n'okpuru microscope mgbe niile. Enwere ike ihu ya naanị na microscope siri ike nke akpọrọ microscope elektrọn.

Obere mgbanwe ọrịa bụ ihe kachasị akpata ọrịa nephrotic na ụmụaka. A na-ahụkwa ya na ndị okenye nwere ọrịa nephrotic, mana ọ bụ obere ihe.

Amaghị ihe kpatara ya, mana ọrịa ahụ nwere ike ịpụta ma ọ bụ metụtara:

• Mmeghachi omume nfụkasị ahụ
• Ojiji nke NSAIDs
• Tumo
• Gba ọgwụ mgbochi (ọrịa na pneumococcal, ọ bụ ezie na ọ dị obere)
• Ọrịa nje virus

Enwere ike ịnwe mgbaàmà nke ọrịa nephrotic, gụnyere:

• Amfụfụ ọdịdị nke mmamịrị
• Agụụ na-adịghị mma
• Mgbapu (karịsịa gburugburu anya, ụkwụ, na nkwonkwo ụkwụ, na afọ)
• Ibu ibu (site na njigide mmiri)

Obere mgbanwe ọrịa anaghị belata oke mmamịrị emepụtara. Ọ naghị adịkarị na ọdịda akụrụ.

Onye nlekọta ahụike nwere ike ọ gaghị enwe ike ịhụ akara ọ bụla nke ọrịa ahụ, ewezuga ọzịza. Ọbara na mmamịrị na-ekpughe ihe ịrịba ama nke ọrịa nephrotic, gụnyere:

• Cholesterol dị elu
• Akwa protein n’ime mmamịrị
• Ọdịdị dị ala nke albumin n’ọbara

A akụrụ biopsy na nnyocha nke anụ ahụ na ihe elektrọn microscope nwere ike na-egosi ihe ịrịba ama nke di ntakiri mgbanwe ọrịa.

Ọgwụ ndị a na-akpọ corticosteroids nwere ike ịgwọ ọrịa ntakịrị mgbanwe n'ọtụtụ ụmụaka. Childrenfọdụ ụmụaka nwere ike chọọ ịnọ na steroid iji mee ka ọrịa ahụ ghara ịlaghachi.

Steroid na-arụ ọrụ nke okenye, mana obere ụmụaka. Ndị okenye nwere ike ịnwe nlọghachi ugboro ugboro wee dabere na steroid.

Ọ bụrụ na ndị steroid anaghị arụ ọrụ, onye na-eweta ọrụ ahụ ga-atụ aro ọgwụ ndị ọzọ.

Enwere ike ịgwọ ọzịza:

• Ọgwụ ACE
• Ọbara mgbali elu
• Diuretics (ọgwụ ọgwụ)

Enwere ike ịgwa gị belata nnu nnu na nri gị.

Usuallymụaka na-anabatakarị corticosteroid karịa ndị okenye. Oftenmụaka na-azakarị n'ime ọnwa mbụ.

Ndaghachi azụ nwere ike ime. Ọnọdụ ahụ nwere ike ịka mma mgbe ọgwụgwọ ogologo oge na corticosteroids na ọgwụ ndị na-egbochi usoro mgbochi (immunosuppressants).

Kpọọ onye na-eweta gị ma ọ bụrụ:

• Develop mepee mgbaàmà nke ntakịrị mgbanwe mgbanwe
• Have nwere nsogbu a na mgbaàmà gị na-akawanye njọ
• Develop mepụtara mgbaàmà ọhụụ, gụnyere nsonaazụ sitere na ọgwụ eji agwọ ọrịa ahụ

Obere mgbanwe nephrotic syndrome; Ọrịa Nil; Lipoid nephrosis; Ọrịa nephrotic Idiopathic nke nwata

• Glomerulus na nephron

Appel GB, Radhakrishnan J, D'Agati VD. Secondary glomerular ọrịa. Na: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner na Rector nke akụrụ. Nke 11. Philadelphia, PA: Elsevier; 2020: isi 32.

Ọrịa Erkan E. Nephrotic. Na: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Akwụkwọ ọgụgụ nke Ọrịa edimụaka. 21nke. Philadelphia, PA: Elsevier; 2020: isi 545.