Rhabdomyolysis

Rhabdomyolysis bụ mmebi nke anụ ahụ anụ ahụ nke na-eduga nhapụ nke akwara muscle dị n'ime ọbara. Ihe ndị a na-emebi akụrụ ma na-ebutekarị akụrụ.

Mgbe akwara mebiri, protein a na - akpọ myoglobin na - ewepụta n’ime ọbara. Mgbe ahụ, akụrụ na-asachapụ ya n’ahụ́. Myoglobin na-agbari n’ime ihe nwere ike imebi mkpụrụ ndụ akụrụ.

Rhabdomyolysis nwere ike ibute site na mmerụ ahụ ma ọ bụ ọnọdụ ọ bụla ọzọ nke na-emebi akwara skelet.

Nsogbu ndị nwere ike ibute ọrịa a gụnyere:

• Nsogbu ma ọ bụ azọpịa mmerụ ahụ
• Iji ọgwụ ọjọọ eme ihe dịka cocaine, amphetamines, statins, heroin, or PCP
• Ọrịa mkpụrụ ndụ ihe nketa
• Oké okpomọkụ
• Ischemia ma ọ bụ ọnwụ nke anụ ahụ
• Low phosphate etoju
• Ọdịdọ ma ọ bụ ịma jijiji ahụ
• Nnukwu ike, dị ka ịgba ọsọ marathon ma ọ bụ calisthenics
• Usoro ịwa ahụ ogologo oge
• Oké ịkpọ nkụ

Mgbaàmà nwere ike ịgụnye:

• Ọchịchịrị, ọbara ọbara, ma ọ bụ cola dị iche iche
• Mbelata mmepụta mmamịrị
• General adịghị ike
• Akwara isi ma ọ bụ aching (myalgia)
• Mkpụrụ obi
• Adịghị ike nke akwara emetụta

Mgbaàmà ndị ọzọ nwere ike ịpụta na ọrịa a:

• Ike ọgwụgwụ
• Nkwonkwo mgbu
• Ọdịdọ
• Ibu ibu (n'amaghi ama)

Nyocha nke anụ ahụ ga-egosiputa akwara ma ọ bụ nke mebiri emebi.

Enwere ike ịme ule ndị a:

• Creatine kinase (CK) larịị
• Ọbara calcium
• Ọbara myoglobin
• Ọbara potassium
• Urinalysis
• Mmamịrị myoglobin ule

Ọrịa a nwekwara ike imetụta nsonaazụ nke ule ndị a:

• CK isoenzymes
• Ọbara creatinine
• Mmamịrị creatinine

Kwesiri ịnweta mmiri nwere bicarbonate iji nyere aka gbochie mmebi akụrụ. Nwere ike ịnweta mmiri site na akwara (IV). Fọdụ ndị mmadụ nwere ike ịchọ ịrịa ọrịa akụrụ.

Onye na - ahụ maka ahụike gị nwere ike kọpụta ọgwụ gụnyere mamịrị mamịrị na bicarbonate (ma ọ bụrụ na mmamịrị zuru ezu).

A ga-emeso Hyperkalemia na ọkwa calcium dị ala (hypocalcemia) ozugbo. E kwesịkwara ịgwọ ọdịda akụrụ.

Nsonaazụ dabere na ọnụọgụ akụrụ. Nnukwu akụrụ odida pụtara ọtụtụ ndị. Inweta ọgwụgwọ n'oge na-adịghị anya rhabdomyolysis ga-ebelata ihe ize ndụ nke mmebi akụrụ na-adịgide adịgide.

Ndị nwere obere nsogbu nwere ike ịlaghachi n'ihe ha na-eme n'ime izu ole na ole ruo otu ọnwa. Otú ọ dị, ụfọdụ ndị na-anọgide na-enwe nsogbu na ike ọgwụgwụ na mgbu mgbu.

Nsogbu nwere ike ịgụnye:

• Nnukwu tubular necrosis
• Nnukwu akụrụ odida
• Ọdịmma kemịkal na-emerụ ahụ n'ọbara
• Ujo (ọbara mgbali elu)

Kpọọ onye na-eweta gị ma ọ bụrụ na ị nwere mgbaàmà nke rhabdomyolysis.

A pụrụ izere Rhabdomyolysis site na:

• Ụ mmiri ọ afterụ afterụ mgbe mmega ahụ siri ike.
• Iwepu uwe ndi ozo na imikpu aru n'ime mmiri oyi ma obu ogwugwo oku.

• Akụrụ anatomi

Haseley L, Jefferson JA. Pathophysiology na etiology nke nnukwu mmerụ akụrụ. Na: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Comprehensive Clinical Nephrology. Nke isii. Philadelphia, PA: Elsevier; 2019: isi 66.

O'Connor FG, Deuster PA. Rhabdomyolysis. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke iri abụọ na ise. Philadelphia, PA: Elsevier; 2020: isi 105.

Parekh R. Rhabdomyolysis. Na: Mgbidi RM, Hockberger RS, Gausche-Hill M, eds. Ngwọta Mberede nke Rosen: Echiche na usoro ọgwụgwọ. Agba nke 9. Philadelphia, PA: Elsevier; 2018: isi 119.