IgA vasculitis - Henoch-Schönlein purpura

IgA vasculitis bụ ọrịa na-agụnye ntụpọ na-acha odo odo na anụ ahụ, nkwonkwo mgbu, nsogbu eriri afọ, na glomerulonephritis (ụdị ọrịa akụrụ). A makwaara ya dị ka Henoch-Schönlein purpura (HSP).

IgA vasculitis na-ebute site na mmeghachi omume na-adịghị mma nke usoro ahụ ji alụso ọrịa ọgụ. Nsonaazụ bụ mbufụt na arịa microscopic na anụ ahụ. Akwara metụta arịa ọbara dị na nkwonkwo, akụrụ, ma ọ bụ eriri afọ. O doghi anya ihe kpatara nke a.

A na-ahụkarị ọrịa a na ụmụaka nọ n'agbata afọ 3 na 15, mana enwere ike ịhụ ya na ndị okenye. Ọ bụkarị ụmụ nwoke ka a na-ahụkarị karịa ụmụ agbọghọ. Ọtụtụ ndị na - ebute ọrịa a nwere ọrịa iku ume n’elu izu ndị gara aga.

Mgbaàmà na atụmatụ nke IgA vasculitis nwere ike ịgụnye:

• Odo odo na anụ ahụ (purpura). Nke a na-eme n'ihe fọrọ nke nta ka ọ bụrụ ụmụaka nile nwere ọnọdụ a. Nke a na-apụtakarị na mgbatị, ụkwụ ala, na ikpere aka.
• Ime mgbu.
• Nkwonkwo mgbu.
• Mmamịrị na-adịghị mma (nwere ike ọ nweghị ihe mgbaàmà).
• Afọ ọsịsa, mgbe ụfọdụ ọbara.
• Hives ma ọ bụ angioedema.
• Ọgbọ na ọgbụgbọ.
• Ọza na mgbu na scrotum nke ụmụ nwoke.
• Isi ọwụwa.

Onye nlekọta ahụike ga-eleba ahụ gị anya na lebara akpụkpọ gị. Nnyocha ahụ ga-egosi ọnya anụ ahụ (purpura, ọnya) na ịdị nro dị nro.

Ule nwere ike ịgụnye:

• Urinalysis kwesịrị mere niile ikpe.
• Ọnwụ ọbara zuru ezu. Platelet nwere ike ịbụ nkịtị.
• Nnwale coagulation: ndị a kwesịrị ịdị nkịtị.
• Biopsy skin, karịsịa ndị okenye.
• Nyocha ọbara na-achọ ihe ndị ọzọ na-akpata mbufụt ọbara, dị ka systemic lupus erythematosus, ọrịa vasculitis metụtara ANCA ma ọ bụ ịba ọcha n'anya.
• Na ndị okenye, a ghaghị ime biopsy akụrụ.
• Nyocha nke afọ nke afọ ma ọ bụrụ na mgbu dị.

Enweghị ọgwụgwọ a kapịrị ọnụ. Ọtụtụ ikpe na-apụ naanị ha. Nkwonkwo mgbu nwere ike ịbawanye mma na NSAID dị ka naproxen. Ọ bụrụ na mgbaàmà adịghị akwụsị, enwere ike ịnye gị ọgwụ corticosteroid dị ka prednisone.

Ọrịa na-akaakarị mma n’onwe ya. Otu ụzọ n'ụzọ atọ nke ụmụaka nwere IgA vasculitis nwere naanị otu ihe. Otu ụzọ n'ụzọ atọ nke ụmụaka nwere ọtụtụ ngosipụta. Ndị mmadụ kwesịrị ịnwe nlekọta ahụike dị nso maka ọnwa 6 ka emesịrị ga-achọ ihe ịrịba ama nke ọrịa akụrụ. Ndị okenye nwere ihe ize ndụ ka ukwuu nke ịrịa ọrịa akụrụ na-adịghị ala ala.

Nsogbu nwere ike ịgụnye:

• Ọbara ọgbụgba n'ime ahụ
• Na-egbochi eriri afọ (na ụmụaka)
  
• Nsogbu akụrụ (na obere okwu)

Kpọọ onye na-eweta gị ma ọ bụrụ:

• Develop mepụtara mgbaàmà nke IgA vasculitis, ha na-adịgide ruo ihe karịrị ụbọchị ole na ole.
• Have nwere mmamịrị acha ma ọ bụ mmamịrị dị ala mgbe emechara.

Immunoglobulin A vasculitis; Leukocytoclastic vasculitis; Henoch-Schönlein purpura; HSP

• Henoch-Schonlein purpura na ụkwụ ala
• Henoch-Schonlein purpura
• Henoch-Schonlein purpura
• Henoch-Schonlein purpura
• Henoch-Schonlein purpura n'ụkwụ nwa ọhụrụ
• Henoch-Schonlein purpura n'ụkwụ nwa ọhụrụ
• Henoch-Schonlein purpura n'ụkwụ nwa ọhụrụ
• Henoch-Schonlein purpura na ụkwụ

Arntfield RT, Hicks mm. Lupus erythematosus sistemụ na vasculitides. Na: Mgbidi RM, Hockberger RS, Gausche-Hill M, eds. Ngwọta Mberede nke Rosen: Echiche na usoro ọgwụgwọ. Agba nke 9. Philadelphia, PA: Elsevier; 2018: isi 108.

Dinulos JGH. Hypersensitivity syndromes na vasculitis. Na: Habif TP, Dinulos JGH, Chapman MS, Zug KA, eds. Ọrịa Skin: Nchoputa na Ọgwụgwọ. Agba nke anọ. Philadelphia, PA: Elsevier; 2018: isi 11.

Feehally J, FLoege J. Immunoglobulin A nephropathy na IgA vasculitis (Henoch-Schönlein purpura). Na: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Comprehensive Clinical Nephrology. Nke isii. Philadelphia, PA: Elsevier; 2019: isi 23.

Hahn D, Hodson EM, Willis NS, Craig JC. Ntughari maka igbochi na ịgwọ ọrịa akụrụ na Henoch-Schönlein purpura (HSP). Cochrane Database Syst Mkpu. 2015; (8): CD005128. PMID: 26258874 www.ncbi.nlm.nih.gov/pubmed/ 26258874.

Lu S, Liu D, Xiao J, et al. Nkọwa n'etiti ndị okenye na ụmụaka Henoch-Schönlein purpura nephritis. Pediatr Nephrol. 2015; 30 (5): 791-796. PMID: 25481021 www.ncbi.nlm.nih.gov/pubmed/25481021.

Patterson JW. Reactionkpụrụ mmeghachi omume vasculopathic. Na: Patterson JW, ed. Weedon's Skin Ọrịa. Agba nke anọ. Philadelphia, PA: Elsevier Churchill Livingstone; 2016: isi 8.

Sunderkötter CH, Zelger B, Chen KR, et al. Nomenclature nke vasculitis na-egbu egbu: Mgbakwunye dermatologic na 2012 nke International Chapel Hill Consensus Conference Nomenclature nke Vasculitides. Ogbu na nkwonkwo Rheumatol. 2018; 70 (2): 171-184. PMID: 29136340 www.ncbi.nlm.nih.gov/pubmed/29136340.