Ọrịa ogbu na nkwonkwo Psoriatic

Ọrịa ogbu na nkwonkwo bụ nsogbu nkwonkwo (ogbu na nkwonkwo) nke na -enwekarị ọnọdụ akpụkpọ akpọrọ psoriasis.

Psoriasis bụ nsogbu anụ ahụ nkịtị na-akpata uhie uhie na akpụkpọ ahụ. Ọ bụ ọnọdụ na-aga n'ihu (na-adịghị ala ala) mkpali. Ogbu na nkwonkwo Psoriatic pụtara na ihe dịka 7% na 42% nke ndị nwere psoriasis. Ntu psoriasis nwere njikọ na ọrịa ogbu na nkwonkwo psoriatic.

N'ọtụtụ ọnọdụ, psoriasis na-abịa tupu ogbu na nkwonkwo. N'ime mmadụ ole na ole, ọrịa ogbu na nkwonkwo na-abịa tupu ọrịa anụ ahụ. Agbanyeghị, inwe ọrịa psoriasis siri ike gbasaa gbasaa na-eme ka ohere ịnweta ọrịa ogbu na nkwonkwo psoriatic mụbaa.

Amaghị ihe kpatara ọrịa ogbu na nkwonkwo psoriatic. Mkpụrụ ndụ ihe nketa, usoro ahụ ji alụso ọrịa ọgụ, na ihe ndị metụtara gburugburu ebe obibi pụrụ iso rụọ ọrụ. O yikarịrị ka ọrịa anụ ahụ na nkwonkwo nwere ike ịbụ ihe kpatara ya. Otú ọ dị, ha nwere ike ọ gaghị emekọ ọnụ.

Ọrịa ogbu na nkwonkwo nwere ike ịdị nro ma nwee naanị nkwonkwo ole na ole. Nkwonkwo na njedebe nke mkpịsị aka ma ọ bụ mkpịsị ụkwụ nwere ike ịmetụta karịa. Ọrịa ogbu na nkwonkwo na-abụkarị ihe na-enweghị isi na-akpata ọrịa ogbu na nkwonkwo naanị n'otu akụkụ ahụ.

Na ụfọdụ ndị, ọrịa ahụ nwere ike ịdị njọ ma na-emetụta ọtụtụ nkwonkwo, gụnyere spain. Mgbaàmà dị na spain gụnyere nkwesi ike na mgbu. Ha na-apụtakarị na ọkpụkpụ azụ na sacrum.

Fọdụ ndị nwere ọrịa ogbu na nkwonkwo psoriatic nwere ike ịnwe mbufụt nke anya.

Ọtụtụ oge, ndị mmadụ na-arịa ogbu na nkwonkwo psoriatic nwere anụ ahụ na ntu ntu nke psoriasis. Ọtụtụ mgbe, akpụkpọ ahụ na-akawanye njọ n'otu oge dị ka ọrịa ogbu na nkwonkwo.

Tendons nwere ike ịrịa ọrịa ogbu na nkwonkwo psoriatic. Ihe atụ gụnyere akwara Achilles, plantar fascia, na akwara n'ọbọ dị n'aka.

N'oge nyocha anụ ahụ, onye nlekọta ahụike ga-achọ:

• Ọzịza nkwonkwo
• Akpịrị akpụkpọ ahụ (psoriasis) na olulu na mbọ
• Obi ọmịiko
• Mbufụt ke enyịn

Enwere ike ịme ụzarị ọkụ ọzọ.

Enweghị nnwale ọbara akọwapụtara maka ọrịa ogbu na nkwonkwo psoriatic ma ọ bụ maka psoriasis. Enwere ike ịme ule iji wepụ ụdị ọrịa ogbu na nkwonkwo ndị ọzọ:

• Rheumatoid ihe
• Ihe mgbochi anti-CCP

Onye na-eweta ọrụ ahụ nwere ike ịnwale mkpụrụ ndụ ihe nketa a na-akpọ HLA-B27 Ndị mmadụ na itinye aka na azụ nwere ike ịnwe HLA-B27.

Onye na-enye gị nwere ike inye ọgwụ ndị na-egbochi ọgwụ ọjọọ (NSAIDs) iji belata ihe mgbu na ọzịza nke nkwonkwo.

Ọrịa ogbu na nkwonkwo nke na-adịghị mma na NSAID ga-achọ ọgwụgwọ na ọgwụ ndị a na-akpọ ọgwụ antirheumatic na-agbanwe ọrịa (DMARDs). Ndị a gụnyere:

• Methotrexate
• Leflunomide
• Sulfasalazine

Apremilast bụ ọgwụ ọzọ eji agwọ ọrịa ogbu na nkwonkwo psoriatic.

Ọgwụ ọgwụ ọhụrụ na-arụ ọrụ dị mma maka ọrịa ogbu na nkwonkwo na-aga n'ihu nke na-anaghị achịkwa DMARDs. Ọgwụ ndị a na - egbochi protein a na - akpọ tumo necrosis factor (TNF). Ha na-enyekarị aka maka ọrịa anụ ahụ yana ọrịa nkwonkwo nke ọrịa ogbu na nkwonkwo psoriatic. A na-enye ọgwụ ndị a ọgwụ ogwu.

Ọgwụ ndị ọhụrụ na-ahụ maka ndu na-agwọ ọrịa ogbu na nkwonkwo nke na-aga n'ihu ọbụlagodi iji ndị DMARD ma ọ bụ ndị ọrụ TNF mgbochi. A na-enyekwa ọgwụ ndị a site na ogwu ogbugba.

Enwere ike iji ọgwụ mgbochi steroid gwọọ nkwonkwo na-egbu mgbu nke ukwuu. A na-eji ha eme ihe mgbe naanị otu ma ọ bụ obere nkwonkwo aka. Ọtụtụ ndị ọkachamara anaghị akwado corticosteroids ọnụ maka psoriatic ogbu na nkwonkwo. Ojiji ha nwere ike ime ka ọrịa psoriasis ka njọ ma gbochie mmetụta nke ọgwụ ndị ọzọ.

N'ọnọdụ ndị na-adịkarịghị, ịwa ahụ nwere ike ịdị mkpa iji mezie ma ọ bụ dochie nkwonkwo mebiri emebi.

Ndị mmadụ nwere ọzịza nke anya kwesịrị ịhụ onye nyocha anya.

Onye na-enye gị nwere ike tụọ aro maka ezumike na mmega ahụ. Usoro ọgwụgwọ anụ ahụ nwere ike inye aka mee ka njikọta njikọta. Nwekwara ike iji ọgwụgwọ okpomọkụ na oyi.

Ọrịa ahụ na-adị nwayọọ mgbe ụfọdụ ma na-emetụta nanị nkwonkwo ole na ole. Otú ọ dị, ọtụtụ ndị nwere ọrịa ogbu na nkwonkwo psoriatic na-emebi nkwonkwo na-eme n'ime ọtụtụ afọ mbụ. N’ebe ụfọdụ nọ, ọrịa ogbu na nkwonkwo nke na-adịkarị njọ nwere ike ịkpata nrụrụ na aka, ụkwụ, na spain.

Imirikiti ndị nwere ọrịa ogbu na nkwonkwo nke na-adịghị emeziwanye na NSAID kwesịrị ịhụ onye na-ahụ maka ọrịa na-arịa ọrịa ogbu na nkwonkwo, yana onye na-agwọ ọrịa maka psoriasis.

Usoro ọgwụgwọ mbu nwere ike belata ihe mgbu ma gbochie mmebi njikọ, ọbụlagodi n'ọnọdụ ndị dị oke njọ.

Kpọọ onye na-eweta gị ma ọ bụrụ na ị mepee mgbaàmà nke ogbu na nkwonkwo yana psoriasis.

Ogbu na nkwonkwo - psoriatic; Psoriasis - psoriatic ogbu na nkwonkwo; Spondyloarthritis - psoriatic ogbu na nkwonkwo; Ọma

• Psoriasis - guttate na ogwe aka na obi
• Psoriasis - guttate na agba

Bruce IN, Ho PYP. Atụmatụ ahụike nke ọrịa ogbu na nkwonkwo psoriatic. Na: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. Nke 7. Philadelphia, PA: Elsevier; 2019: isi nke 128.

Gladman D, Rigby W, Azevedo VF, et al. Tofacitinib maka ọrịa ogbu na nkwonkwo psoriatic na ndị ọrịa nwere azịza na-ezighi ezi nye ndị na-emechi TNF. N Engl J Ahụike. 2017; 377:1525-1536.

Smolen JS, Schöls M, Braun J, et al. Na Na Na Na Na Na Na Na Na Na Na-emeso spondyloarthritis axis na spondyloarthritis nke dị n'akụkụ, karịsịa ọrịa ogbu na nkwonkwo psoriatic, iji dozie: Nwelite 2017 nke nkwenye site n'aka ndị ọrụ mba ụwa. Ann Rheum Dis. 2018; 77 (1): 3-17. PMID: 28684559 pubmed.ncbi.nlm.nih.gov/28684559/.

Veale DJ, Orr C. Nchịkwa nke ogbu na nkwonkwo psoriatic. Na: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. Nke 7. Philadelphia, PA: Elsevier; 2019: isi 131.