Ọrịa thyroid - carcinoma medullary
Ọrịa carcinoma nke Medullary nke ọrịa thyroid bụ ọrịa cancer nke na-amalite na sel ndị na-ewepụta hormone a na-akpọ calcitonin. A na - akpọ sel ndị a “C”. Ọkpụkpụ thyroid dị n'ime n'ihu obere olu gị.
Ebughi ihe kpatara carcinoma medullary nke thyroid (MTC). MTC dị obere. O nwere ike ime na ụmụaka na ndị okenye.
N'adịghị ka ụdị ọrịa cancer thyroid ndị ọzọ, ọ ga-abụrịrị na MTC ga-ebute site na ọgwụgwọ radiation na olu enyere iji gwọọ ọrịa cancer ndị ọzọ n'oge nwata.
E nwere ụdị abụọ nke MTC:
- MTC, na-adịghị agba n'ezinụlọ. Imirikiti MTCs bụ oge ụfọdụ. Formdị a na-emetụta ndị okenye.
- MTC nketa, nke na-agba n'ime ezinụlọ.
Have nwere nnukwu ihe egwu maka ụdị ọrịa kansa a ma ọ bụrụ na inwee:
- Akụkọ banyere ezinụlọ nke MTC
- A akụkọ ihe mere eme nke ezinụlọ nke otutu endoprine neoplasia (MEN)
- Ihe omuma nke pheochromocytoma, muromal neuromas, hyperparathyroidism ma obu pancreatic endocrine etuto
Dị ọrịa cancer gị ndị ọzọ gụnyere:
- Carcinoma Anaplastic nke thyroid
- Follicular akpụ nke thyroid
- Papillary carcinoma nke thyroid
- Thyroid lymphoma
MTC na-amalitekarị dị ka obere akpụ (nodule) na thyroid gland. Enwekwara ike inwe ọnya lymph na-agbapụta n'olu. N'ihi ya, ihe mgbaàmà nwere ike ịgụnye:
- Ọzịza nke olu
- Arsda ụda
- Nsogbu iku ume n'ihi na ikuku nke ikuku
- .Kwara
- Ume na ọbara
- Afọ ọsịsa n'ihi ọkwa dị elu nke calcitonin
Onye nlekọta ahụike gị ga-eme nyocha anụ ahụ wee jụọ maka ihe mgbaàmà gị na akụkọ ahụike gị.
Ule ndị nwere ike iji chọpụta MTC gụnyere:
- Nnwale ọbara Calcitonin
- Nyocha CEA
- Nnwale mkpụrụ ndụ ihe nketa
- Bioroid na-egbu egbu
- Ultrasound nke thyroid na lymph ọnụ nke olu
- PET nyocha
Ndị mmadụ nwere MTC kwesịrị ịlele maka ụfọdụ etuto ndị ọzọ, ọkachasị pheochromocytoma na etuto parathyroid na akpụ parathyroid.
Ọgwụgwọ gụnyere ịwa ahụ iji wepu gland thyroid na lymph nodes. Ebe ọ bụ na nke a bụ akpụ a na-ahụkarị, a ga-awa ahụ site n'aka dọkịta na-awa ahụ maara ụdị ọrịa kansa a ma nwee ọrụ achọrọ.
Usoro ọgwụgwọ ọzọ ga-adabere na ọkwa calcitonin gị. Nrịgo elu na ọkwa calcitonin nwere ike igosipụta uto ọhụrụ nke ọrịa kansa.
- Chemotherapy na radieshon anaghị arụ ọrụ nke ọma maka ụdị ọrịa kansa a.
- A na-eji radieshon eme ihe na ụfọdụ ndị mmadụ ka a wachara ha ahụ.
- Ọgwụ ndị ezubere iche ọhụụ nwere ike belata uto tumọ. Onye na-eweta gị nwere ike ịgwa gị ihe ndị ọzọ gbasara ndị a ma ọ bụrụ na ọ dị mkpa.
Ezigbo ndị ikwu nke ndị a chọpụtara na ụdị ihe nketa nke MTC nọ n'ihe ize ndụ dị ukwuu nke kansa a ma soro ndị na-enye ha kwurịtara.
Nwere ike belata nchekasị nke ọrịa site na isonyere ndị otu na-akwado ọrịa kansa. Kọrọ ndị ọzọ ihe ha na-eme na nsogbu niile nwere ike inyere gị aka ichewe naanị gị.
Imirikiti ndị nwere MTC na-ebi ma ọ dịkarịa ala afọ 5 mgbe nchoputa, dabere na ọkwa nke kansa. Afọ ndụ 10 afọ bụ 65%.
Nsogbu nwere ike ịgụnye:
- Ọrịa cancer na-agbasa n'akụkụ ndị ọzọ nke ahụ
- A na-ewepụ gland parathyroid na mberede n'oge ịwa ahụ
Kpọọ onye na-eweta gị ma ọ bụrụ na ị nwere mgbaàmà nke MTC.
Mgbochi nwere ike ọ gaghị ekwe omume. Mana, ịmara ihe kpatara nsogbu gị, ọkachasị akụkọ ntolite ezinụlọ gị, nwere ike ikwe ka nchoputa na ọgwụgwọ oge mbụ. Maka ndị mmadụ nwere ezigbo ezinụlọ akụkọ ihe mere eme nke MTC, a ga-atụ aro nhọrọ iji wepu gland thyroid. Kwesịrị iji nlezianya kwurịta nhọrọ a na dọkịta maara ọrịa ahụ nke ọma.
Thyroid - medullary carcinoma; Ọrịa cancer - thyroid (medullary carcinoma); MTC; Thyroid nodule - medullary
- Ọrịa thyroid gị - CT scan
- Gland gland
Jonklass J, Cooper DS. Thyroid. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke 26th. Philadelphia, PA: Elsevier; 2020: isi 213.
Weebụsaịtị National Cancer Institute. Usoro ọgwụgwọ ọrịa cancer nke thyroid (okenye) (PDQ) - ụdị ọkachamara ahụike. www.cancer.gov/types/thyroid/hp/thyroid-treatment-pdq. Emelitere Jenụwarị 30, 2020. Nabata March 6, 2020.
Smith PW, Hanks LR, Salomone LJ, Hanks JB. Thyroid. Na: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Akwụkwọ Sabiston nke gerywa Ahụ. Agba nke 20. Philadelphia, PA: Elsevier Saunders; 2017: isi 36.
Viola D, Elisei R. Nchịkwa nke ọrịa cancer thyroid. Endocrinol Metab Nyocha North Am. 2019; 48 (1): 285-301. PMID: 30717909 pubmed.ncbi.nlm.nih.gov/30717909/.
Wells SA Jr, Asa SL, Dralle H. Revised American Thyroid Association ntuziaka maka njikwa nke medullary thyroid carcinoma. Thyroid. 2015; 25 (6): 567-610. PMID: 25810047 pubmed.ncbi.nlm.nih.gov/25810047/.