Ọrịa Carcinoid

Ọrịa Carcinoid bụ otu mgbaàmà metụtara ọrịa cancer carcinoid. Ndị a bụ etuto ahụ nke eriri afọ, eriri afọ, appendix, na akpa ume bronchial dị na ngụgụ.

Ọrịa Carcinoid bụ usoro nke mgbaàmà mgbe ụfọdụ a na-ahụ ndị nwere akpụ carcinoid. Mkpụrụ etuto ndị a adịkarịghị, ọ na - etokarị nwayọ. A na-ahụ ọtụtụ etuto ahụ carcinoid na akụkụ eriri afọ na ngụgụ.

Ọrịa Carcinoid na-eme na mmadụ ole na ole nwere akpụ carcinoid, mgbe etolitere ọrịa ahụ na imeju ma ọ bụ ngụgụ.

Mkpụrụ ọgwụ ndị a na-ahapụ ọtụtụ serotonin homonụ, yana ọtụtụ kemịkal ndị ọzọ. Na homonụ ahụ na-eme ka akwara ọbara meghee (dilate). Nke a na - akpata ọrịa carcinoid.

Ọrịa carcinoid nwere isi mgbaàmà anọ gụnyere:

• Flushing (ihu, olu, ma ọ bụ obi elu), dị ka arịa ọbara sara mbara nke a hụrụ na akpụkpọ ahụ (telangiectasias)
• Ike iku ume, dị ka iku ume
• Afọ ọsịsa
• Nsogbu obi, dịka ịmịkọrọ valvụ obi, ịkụda obi nwayọ, obere ma ọ bụ ọbara mgbali elu

A na - ebute ihe mgbaàmà mgbe ụfọdụ site na mgbatị anụ ahụ, ma ọ bụ iri nri ma ọ bụ ị drinkingụ ihe ọ suchụ suchụ dịka cheese, chocolate, ma ọ bụ mmanya uhie.

A na-ahụ ọtụtụ etuto ahụ mgbe a na-eme nyocha ma ọ bụ usoro maka ihe ndị ọzọ, dịka n'oge ịwa ahụ afọ.

Ọ bụrụ na emere nyocha anụ ahụ, onye nlekọta ahụike nwere ike ịchọta akara nke:

• Nsogbu obi, dịka ntamu
• Niacin-erughi ọrịa (pellagra)

Ule nke enwere ike ime gunyere:

• 5-HIAA ọkwa na mmamịrị
• Nyocha ọbara (gụnyere serotonin na ule ọbara chromogranin)
• Nyocha CT na MRI nke obi ma ọ bụ afọ
• Ihe omumu
• Nyocha a na-enyocha Octreotide radiolabeled

Gerywa ahụ iji wepu akpụ ahụ na-abụkarị ọgwụgwọ mbụ. Ọ nwere ike gwọọ ọrịa ahụ kpamkpam ma ọ bụrụ na ewepụrụ akpụ ahụ kpamkpam.

Ọ bụrụ na akpụ ahụ agbasawo na imeju, ọgwụgwọ gụnyere otu n'ime ihe ndị a:

• Wepụ akụkụ nke imeju nwere mkpụrụ ndụ akpụ
• Na-eziga (inye ọgwụ) ọgwụ n'ime imeju iji bibie etuto ahụ

Mgbe enweghi ike iwepu akụrụngwa ahụ niile, iwepụ akụkụ buru ibu nke tumo ("debulking") nwere ike inye aka belata mgbaàmà ahụ.

Ọgwụ Octreotide (Sandostatin) ma ọ bụ lanreotide (Somatuline) ka a na-enye ndị nwere akpụ akpụ carcinoid dị elu nke enweghị ike wepu ya na ịwa ahụ.

Ndị nwere ọrịa carcinoid kwesịrị izere mmanya na-aba n'anya, nnukwu nri, na nri dị elu na tyramine (chiiz ochie, ube oyibo, ọtụtụ nri esichara), n'ihi na ha nwere ike ịkpalite mgbaàmà.

Medicinesfọdụ ọgwụ ndị a na-ahụkarị, dị ka ndị na-emechi serotonin reuptake inhibitors (SSRIs), dị ka paroxetine (Paxil) na fluoxetine (Prozac), nwere ike ime ka mgbaàmà ka njọ site na ịba ụba nke serotonin. Agbanyeghị, Kwụsị ị takingụ ọgwụ ndị a belụsọ ma ndị na-eweta gị agwa gị ka ị mee ya.

Mụtakwuo banyere ọrịa carcinoid ma nweta nkwado site na:

• Ihe Carcinoid Cancer Foundation - www.carcinoid.org/resources/support-groups/directory/
• Neuroendocrine Tumor Research Foundation - netrf.org/for-patients/

Echiche ndị mmadụ na-arịa ọrịa carcinoid na-adịkarị iche na nke ndị nwere ọrịa carcinoid na-enweghị ọrịa ahụ.

Prognosis na-adabere na saịtị nke etuto. N'ime ndị nwere ọrịa ahụ, etuto ahụ agbasaala nke imeju. Nke a na-ewetu ọnụego lanarị. Ndị nwere ọrịa carcinoid nwekwara ike ịnwe kansa dị iche (akpụ nke abụọ) n'otu oge ahụ. Na mkpokọta, prognosis na-abụkarị ọmarịcha.

Nsogbu nke ọrịa carcinoid nwere ike ịgụnye:

• Ihe ize ndụ dị ukwuu nke ọdịda na mmerụ ahụ (site na ọbara mgbali elu)
• Mgbochi afọ (site na tumo)
• Ọbara afọ
• Mfu obi obi

Formdị na-egbu egbu nke ọrịa carcinoid, nsogbu carcinoid, nwere ike ịpụta dị ka mmetụta dị n'akụkụ nke ịwa ahụ, anesthesia ma ọ bụ chemotherapy.

Kpọtụrụ onye na-ahụ maka ọrụ gị ma ọ bụrụ na ị nwere mgbaàmà nke ọrịa carcinoid.

Gwọ etuto ahụ na-ebelata ohere nke ọrịa carcinoid.

Ọrịa ọrịa; Ọrịa Argentaffinoma

• Mbido Serotonin

Weebụsaịtị National Cancer Institute. Gastrointestinal carcinoid tumors treatment (Okenye) (PDQ) - ụdị ọkachamara ahụike. www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-treatment-pdq. Emelitere September 16, 2020. Nweta October 14, 2020.

Neuroberg K. Neuroendocrine etuto ahụ na nsogbu ndị metụtara ya. Na: Melmed S, Auchus, RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Akwụkwọ ọgụgụ Williams nke Endocrinology. Nke iri na anọ. Philadelphia, PA: Elsevier; 2020: isi 45.

Wolin EM, Jensen RT. Neuroendocrine etuto ahụ. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke 26th. Philadelphia, PA: Elsevier; 2020: isi 219.