Ọrịa Machado Joseph ọ nwere ike ịgwọ?

Ndinaya

• Otu esi eme ọgwụgwọ ahụ
• Kedu ka usoro physiotherapy si eme
• Cannye nwere ike ịrịa ọrịa ahụ
• Kedu ka esi eme nchoputa

Ọrịa Machado-Joseph bụ ọrịa mkpụrụ ndụ na-adịghị ahụkebe nke na-akpata mmebi na-aga n'ihu nke usoro ụjọ ahụ, na-akpata nkwụsị nke njikwa ahụ na nhazi, karịsịa na ogwe aka na ụkwụ.

N'ozuzu, ọrịa a na-apụta mgbe afọ 30 gasịrị, na-edozi nke nta nke nta, na-ebu ụzọ na-emetụta akwara ụkwụ na ogwe aka ma na-aga n'ihu oge karịa akwara ndị na-ahụ maka ikwu okwu, ilo na ọbụna mmegharị anya.

Enweghị ike ịgwọ ọrịa Machado-Joseph, mana enwere ike ijikwa ya site na iji ọgwụ na usoro physiotherapy, nke na-enyere aka belata mgbaàmà ma kwe ka nnwere onwe nke ọrụ kwa ụbọchị.

Otu esi eme ọgwụgwọ ahụ

Ọgwụgwọ maka ọrịa Machado-Joseph ga-abụrịrị onye na-agwọ ọrịa na-eduzi ya ma na-achọkarị iji belata njedebe nke ọrịa ahụ na-ebute.

Ya mere, enwere ike ime ọgwụgwọ na:

• Oriri ọgwụgwọ Parkinson, dị ka Levodopa: enyemaka iji belata njigide nke mmegharị na ịma jijiji;
• Iji antispasmodic ọgwụgwọ, dị ka Baclofeno: ha na-egbochi ọdịdị nke spasms muscular, na-emezi mmegharị ahụ;
• Iji ugogbe anya ma obu idozi anya m: belata ihe isi ike n'ịhụ na ọdịdị nke ọhụụ abụọ;
• Mgbanwe na nri: na-emeso nsogbu metụtara nsogbu isi ike, site na mgbanwe n'ụdị nri, dịka ọmụmaatụ.

Tụkwasị na nke a, dọkịta ahụ nwekwara ike ịkwado ịme usoro ọgwụgwọ anụ ahụ iji nyere onye ọrịa ahụ aka ịkwụsị adịghị ike anụ ahụ ya ma bie ndụ nwere onwe ya n'ịrụ ọrụ kwa ụbọchị.

Kedu ka usoro physiotherapy si eme

A na-eme ọgwụgwọ anụ ahụ maka ọrịa Machado-Joseph site na mmega ahụ mgbe niile iji nyere onye ọrịa aka imeri njedebe nke ọrịa ahụ kpatara. Ya mere, n'oge usoro physiotherapy, enwere ike iji ọrụ dị iche iche, site na ịme mmega iji jigide njupụta nke nkwonkwo, na ịmụ iji klọọkụ ma ọ bụ oche oche, dịka ọmụmaatụ.

Na mgbakwunye, physiotherapy nwekwara ike ịgụnye ilo ọgwụgwọ ọgwụgwọ nke akwadoro yana ihe dị mkpa maka ndị ọrịa niile nwere nsogbu isiri nri, nke metụtara mmebi akwara na-arịa ọrịa ahụ.

Cannye nwere ike ịrịa ọrịa ahụ

Ọrịa Machado-Joseph na-akpata mgbanwe mkpụrụ ndụ ihe nketa nke na-ebute mmepụta nke protein, nke a maara dị ka Ataxin-3, nke na-agbakọta na ụbụrụ ụbụrụ na-akpata mmepe nke ọnya na-aga n'ihu na ọdịdị nke mgbaàmà.

Dị ka nsogbu mkpụrụ ndụ ihe nketa, ọrịa Machado-Joseph bụ ihe a na-ahụkarị n'ọtụtụ mmadụ n'otu ezinụlọ, nwere ohere 50% nke ibufe site na nne na nna nye ụmụaka. Mgbe nke a mere, ụmụaka nwere ike ibute akara mbụ nke ọrịa tupu nne na nna ha.

Kedu ka esi eme nchoputa

N'ọtụtụ ọnọdụ, a na-amata ọrịa Machado-Joseph site na ịlele mgbaàmà site n'aka onye na-agwọ ọrịa na nyocha akụkọ ihe mere eme nke ezinụlọ nke ọrịa ahụ.

Na mgbakwunye, enwere ule ọbara, nke a maara dị ka SCA3, nke na-enye gị ohere ịchọpụta mgbanwe mkpụrụ ndụ ihe nketa na-akpata ọrịa. N'ụzọ ahụ, mgbe ị nwere onye n'ezinaụlọ nwere ọrịa a, ma lee gị ule, ọ ga-ekwe omume ịchọpụta ihe ọghọm nke ịmalite ọrịa ahụ bụkwa.