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Kedu ihe bụ BRAF mkpụrụ ndụ ihe nketa ule?

Nyocha mkpụrụ ndụ BRAF na-achọ mgbanwe, nke a maara dị ka mmụba, na mkpụrụ ndụ ihe nketa a na-akpọ BRAF. Ihe nketa bụ ihe nketa sitere n'aka nne gị na nna gị.

Mkpụrụ ndụ BRAF na-eme protein nke na-enyere aka ịchịkwa uto mkpụrụ ndụ. A maara ya dị ka oncogene. Oncogene na-arụ ọrụ dị ka okpu gas na ụgbọ ala. Dị ka ọ dị, otu oncogene na-agbanye uto sel dị ka ọ dị mkpa. Mana ọ bụrụ na ị nwere ntụgharị BRAF, ọ dị ka pedal gas na-arapara ala, mkpụrụ ndụ ihe nketa enweghị ike ịkwụsị mkpụrụ ndụ na-eto eto. Ọkpụkpụ sel a na - achịkwaghị achịkwa nwere ike ibute ọrịa kansa.

Ọ BRRA na mgbanwe nke BRAF, a ga-eketa nne na nna gị ma ọ bụ nweta ya na nwata. Mmegharị nke na-eme mgbe emechara ndụ na-abụkarị ihe kpatara gburugburu ma ọ bụ site na mmejọ nke na-eme n'ahụ gị n'oge nkewa sel. Ihe nketa nke BRAF dị obere, mana ha nwere ike ibute nnukwu nsogbu ahụike.

Mgbanwe ndị a na - enweta (nke a makwaara dị ka somatic) BRAF bụ ihe a na - ahụkarị. Achọpụtala mmụba ndị a n'ihe dị ka ọkara nke ọrịa melanoma niile, ụdị ọrịa cancer kacha njọ. A na-ahụkarị mgbanwe BRAF na nsogbu ndị ọzọ na ụdị ọrịa kansa dị iche iche, gụnyere ọrịa cancer nke eriri afọ, thyroid, na ovaries. Cancers na mgbanwe BRAF na-adịkarị njọ karịa ndị na-enweghị mmụba.


Aha ndị ọzọ: BRAF gene geneation mutation, Melanoma, BRAF V600 mutation, cobas

Kedu ihe eji ya?

Ule a na-ejikarị achọ maka mgbanwe BRAF na ndị ọrịa nwere melanoma ma ọ bụ ọrịa cancer BRAF ndị ọzọ. Medicinesfọdụ ọgwụ cancer na-arụ ọrụ nke ọma na ndị nwere mmụgharị BRAF. Otu ọgwụ ndị ahụ adịghị arụ ọrụ ma mgbe ụfọdụ dị egwu nye ndị na-enweghị mmụba ahụ.

Enwere ike iji nyocha BRAF hụ ma ọ bụrụ na ị nọ n'ihe ize ndụ maka ọrịa kansa dabere na akụkọ ntolite ezinụlọ yana / ma ọ bụ akụkọ ahụike gị.

Gịnị kpatara m ji chọọ nyocha mkpụrụ ndụ BRAF?

Nwere ike ịchọ nyocha BRAF ma ọ bụrụ na achọpụtala gị na melanoma ma ọ bụ ụdị ọrịa kansa ọzọ. Mara ma ị nwere mmụba ahụ nwere ike inyere onye na-eweta gị aka ịkọwa ọgwụgwọ kwesịrị ekwesị.

Nwekwara ike ịchọ ule a iji hụ ma ị nọ n'ọnọdụ dị elu karịa ịrịa kansa. Ihe ndị dị egwu gụnyere akụkọ gbasara ezinụlọ gbasara ọrịa kansa na / ma ọ bụ nwee ọrịa kansa na nwata. Afọ a kapịrị ọnụ dabere na ụdị ọrịa kansa.


Kedu ihe na-eme n'oge ule mkpụrụ ndụ BRAF?

Imirikiti ule BRAF ka ana eme n’ime usoro akpọrọ tumor biopsy. N'oge biopsy, onye nlekọta ahụike ga-ewepụta obere mpempe akwụkwọ site na ịcha ma ọ bụ ịkpụcha elu etuto ahụ. Ọ bụrụ na onye na-eweta gị chọrọ inyocha akpụ akpụ ahụ n’ime ahụ gị, ọ nwere ike iji agịga pụrụ iche wepụ ihe nlele ahụ.

Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?

Usually na-adịghị mkpa ọ bụla pụrụ iche preparations maka a BRAF ule.

Onwere ihe egwu di n’ule a?

May nwere ike ịnwe ntakịrị ọnya ma ọ bụ ọbara ọgbụgba na saịtị nke biopsy. I nwekwara ike inwe obere ahụ erughị ala na saịtị maka otu ụbọchị ma ọ bụ abụọ.

Kedu ihe nsonaazụ ahụ pụtara?

Ọ bụrụ na ị nwere melanoma ma ọ bụ ụdị ọrịa kansa ọzọ, nsonaazụ ya na-egosi na ị nwere mmụgharị BRAF, onye na-eweta gị nwere ike ịkọwa ọgwụ ndị ezubere iji gbanwee mmụba ahụ. Ọgwụ ndị a nwere ike ịdị irè karịa ọgwụgwọ ndị ọzọ.

Ọ bụrụ na ị nwere melanoma ma ọ bụ ụdị ọrịa kansa ọzọ, nsonaazụ ya na-egosi gị emela nwere mmụgharị, onye na-eweta gị ga-ahuta ụdị ọgwụ dị iche iche iji gwọọ kansa gị.


Ọ bụrụ na ịchọpụtaghị ọrịa kansa na nsonaazụ gị na-egosi na ị nwere mkpụrụ ndụ mkpụrụ ndụ BRAF, ọ adịghị pụtara na ị nwere kansa, mana ị nwere nnukwu nsogbu nke kansa. Mana nyocha ọrịa kansa ugboro ugboro, dị ka nyocha anụ ahụ, nwere ike belata ihe egwu gị. N'oge a na-enyocha akpụkpọ ahụ, onye nlekọta ahụike ga-eleba anya na akpụkpọ ahụ gị dum iji chọpụta maka ntụpọ na uto ndị ọzọ na-enyo enyo.

Gwa onye na - enye gị ọrụ gbasara ihe ndị ọzọ ị ga - eme iji belata ihe egwu gị.

Mụtakwuo maka ule nyocha ụlọ, akara ngosi, na nghọta nsonaazụ.

Onwere ihe ozo m choro ima banyere BRAF test?

Nwere ike ịnụ ka ndị na-eweta gị na-ekwu maka mmụba V600E. E nwere ụdị mmụgharị BRAF dị iche iche. V600E bụ ụdị mgbanwe ụdị BRAF.

Ntughari

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  2. American Cancer Society [Intanet]. Atlanta: American Cancer Society Inc.; c2018. Oncogenes na tumo na-ebelata mkpụrụ ndụ ihe nketa; [emelitere 2014 Jun 25; akpọrọ 2018 Jul 10]; [ihe dị ka ihuenyo 4]. E Nweta site na: https://www.cancer.org/cancer/cancer-causes/genetics/genes-and-cancer/oncogenes-tumor-suppressor-genes.html
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Ejila ozi dị na saịtị a dị ka onye dochie anya nlekọta ahụike ọkachamara ma ọ bụ ndụmọdụ. Kpọtụrụ onye na-ahụ maka ahụike ma ọ bụrụ na ị nwere ajụjụ gbasara ahụike gị.

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