Jụọ ọkachamara ahụ: Understandghọta ọdịdị ala nke ọgwụ maka Ankylosing Spondylitis

Ndinaya

• Enwere ike ịgwọ ọrịa ankylosing?
• Kedu ọgwụgwọ kachasị mma na ọnwụnwa ahụike?
• Kedu ka m ga - esi mara ma m tozuru maka nnwale ahụike?
• Kedu usoro ọgwụgwọ kachasị ọhụrụ maka ankylosing spondylitis?
• Kedu ụdị usoro ọgwụgwọ ndị ị kwadoro? Mmega dị a doaa ka ị na-akwado?
• Surgerywa ahụ ọ bụ nhọrọ maka ịgwọ ọrịa ankylosing spondylitis?
• Kedu ka ị si hụ ọgwụgwọ maka spondylitis ankylosing na-agbanwe n'ime afọ 10 sochirinụ?
• Kedu ihe ị chere ngbanwe ọzọ maka ọgwụgwọ nke ankylosing spondylitis ga-abụ?
• Kedụ ka teknụzụ ọgbara ọhụrụ si enye aka n'ịgwọ ọrịa?

Enwere ike ịgwọ ọrịa ankylosing?

Ka ọ dị ugbu a, enweghị ọgwụgwọ maka ankylosing spondylitis (AS). Agbanyeghị, ọtụtụ ndị ọrịa nwere AS nwere ike ibi ndụ ogologo oge.

N'ihi oge n'etiti mmalite nke mgbaàmà na nkwenye nke ọrịa ahụ, nchoputa oge mbụ dị mkpa.

Nlekọta ahụike, usoro ọgwụgwọ enyemaka ndị ọzọ, yana omume omume ezubere iche nwere ike ịnye ndị ọrịa ndụ ka mma. Mmetụta dị mma na-agụnye nhụjuanya mgbu, mmụba nke mmegharị, na ikike ịrụ ọrụ.

Kedu ọgwụgwọ kachasị mma na ọnwụnwa ahụike?

Ọnwụnwa ahụike kachasị mma bụ ndị na-enyocha nrụpụta na nchekwa nke bimekizumab. Ọ bụ ọgwụ na - egbochi interleukin (IL) -17A na IL-17F - obere protein na - enye aka na mgbaàmà AS.

Filgotinib (FIL) bụ onye na-emechi ihe na-egbochi Janus kinase 1 (JAK1), protein ọzọ nwere nsogbu. FIL na-aga n'ihu ugbu a maka ọgwụgwọ psoriasis, ọrịa ogbu na nkwonkwo psoriatic, na AS. A na-eji ọnụ ekwu ya ma sie ezigbo ike.

Kedu ka m ga - esi mara ma m tozuru maka nnwale ahụike?

Ikike gị tozuru oke na ikpe ụlọ ọgwụ maka AS dabere na ebumnuche nke ikpe ahụ.

Ọnwụnwa nwere ike ịmụ banyere nrụpụta ọrụ na nchekwa nke ọgwụ nyocha, agam n’ihu nke ịkpụkpụ, ma ọ bụ usoro okike nke ọrịa ahụ. Nyochaa usoro nyocha nke AS na-emetụta nhazi nke usoro ọgwụgwọ n'ọdịnihu.

Kedu usoro ọgwụgwọ kachasị ọhụrụ maka ankylosing spondylitis?

Ọhụrụ FDA kwadoro ọgwụ maka ọgwụgwọ nke AS bụ:

• ustekinumab (Stelara), onye mgbochi IL12 / 23
• tofacitinib (Xeljanz), onye mmechi JAK
• secukinumab (Cosentyx), onye mmechi IL-17 na imezi ihe mgbochi monoclonal
• ixekizumab (Taltz), onye na-eme ihe ike IL-17

Kedu ụdị usoro ọgwụgwọ ndị ị kwadoro? Mmega dị a doaa ka ị na-akwado?

Usoro ọgwụgwọ ndị m na-atụ aro ka a gụnye gụnyere:

• ịhịa aka n'ahụ
• igba okpukpu
• acupressure
• omume hydrotherapy

Mmega ahụ pụrụ iche gụnyere:

• ndinyanade mbịne
• mgbidi ịnọ ọdụ
• osisi
• chin tuck na recumbent ọnọdụ
• hip ndinyanade mbịne
• iku ume miri emi ma na ije ije

A na-agbakwa ume ka eji usoro yoga na eriri akwara eletrik na-agagharị (TENS).

Surgerywa ahụ ọ bụ nhọrọ maka ịgwọ ọrịa ankylosing spondylitis?

Wa ahụ dị obere na AS. Mgbe ụfọdụ, ọrịa ahụ na-aga n'ihu ruo n'ókè nke igbochi ihe omume kwa ụbọchị n'ihi nhụjuanya, njedebe nke mmegharị, na adịghị ike. N'okwu ndị a, enwere ike ịkwado ịwa ahụ.

E nwere usoro ole na ole nwere ike ibelata ihe mgbu, mee ka ọkpụkpụ azụ dịkwuo ala, meziwanye ọnọdụ, ma gbochie mkpịsị akwara. Ngwurugwu spain, osteotomies, na laminectomies nke ndị dọkịta na-awa ahụ nke ọma nwere ike ịba uru nye ụfọdụ ndị ọrịa.

Kedu ka ị si hụ ọgwụgwọ maka spondylitis ankylosing na-agbanwe n'ime afọ 10 sochirinụ?

Ọ bụ echiche m na a ga-ahazi ọgwụgwọ dabere na nchọpụta ahụike, usoro ntanetị kachasị mma, na okwu ọ bụla metụtara ọrịa a.

AS dara n'okpuru nche anwụ nke ụdị ọrịa dị iche iche a na-akpọ spondyloarthropathies. Ndị a gụnyere psoriasis, ọrịa ogbu na nkwonkwo psoriatic, ọrịa obi na-afụ ụfụ, na spondyloarthropathy na-emeghachi omume.

Enwere ike ịnwe ihe ngosi crossover nke mpaghara ndị a ma ndị mmadụ ga-erite uru site na usoro ọgwụgwọ ezubere iche.

Kedu ihe ị chere ngbanwe ọzọ maka ọgwụgwọ nke ankylosing spondylitis ga-abụ?

Mkpụrụ ndụ abụọ kpọmkwem, HLA-B27 na ERAP1, nwere ike itinye aka na okwu AS. Echere m na ọganihu ọzọ na ọgwụgwọ nke AS ga-agwa site na ịghọta otú ha si emekọrịta na mkpakọrịta ha na ọrịa obi na-afụ ụfụ.

Kedụ ka teknụzụ ọgbara ọhụrụ si enye aka n'ịgwọ ọrịa?

Otu nnukwu ọganihu dị na nanomedicine. Ejirila teknụzụ a mee ihe nke ọma ịgwọ ọrịa ndị ọzọ na-egbu mgbu dị ka ọrịa ogbu na nkwonkwo na ọrịa ogbu na nkwonkwo. Mmepe nke usoro nnyefe nke nanotechnology nwere ike ibu ihe mgbakwunye na-akpali akpali na njikwa AS.

Brenda B. Spriggs, MD, FACP, MPH, bụ Prọfesọ Clinical Emerita, UCSF, Rheumatology, onye ndụmọdụ maka ọtụtụ ụlọ ọrụ ahụike na onye edemede. Ihe ọdịmma ya gụnyere ịkwado ndidi na agụụ maka ịnye ndị ọkachamara na ndị ọkachamara na ndị ọkachamara na ndị ọkachamara. Ọ bụ onye na-ede akwụkwọ nke "Focus on Your Best Health: Smart Guide to the Health Care You Deserve."