Alfa-Fetoprotein (AFP) Ule

Ndinaya

• Kedu ihe nyocha alpha-fetoprotein (AFP)?
• Kedu ihe eji ya?
• Kedu ihe kpatara m ji chọọ nyocha AFP?
• Kedu ihe na-eme n'oge ule AFP?
• Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?
• Onwere ihe egwu di n’ule a?
• Kedu ihe nsonaazụ ahụ pụtara?
• Onwere ihe ozo m choro ima banyere ule AFP?
• Ntughari

Kedu ihe nyocha alpha-fetoprotein (AFP)?

Alpha-fetoprotein (AFP) bụ protin na-emepụta n’imeju nke nwa ebu n’afọ na-etolite. N'oge uto nwa, ụfọdụ AFP na-agafe placenta wee banye n'ọbara nne. Nnwale nke AFP na-atụle ọkwa AFP n'ime ụmụ nwanyị dị ime n'oge nke atọ nke afọ ime. Oke ma ọ bụ pere mpe AFP n’ime ọbara nne nwere ike bụrụ akara mgbapụ nke ọmụmụ ma ọ bụ ọnọdụ ọzọ. Ndị a gụnyere:

• Ọkpụkpụ neural tube, ọnọdụ dị njọ nke na-akpata ụbụrụ na-adịghị mma nke ụbụrụ nwa na / ma ọ bụ spain
• Down syndrome, ọrịa nke mkpụrụ ndụ ihe nketa na-akpata nkwarụ ọgụgụ isi na igbu oge mmepe
• Insmụ ejima ma ọ bụ ọtụtụ ọmụmụ, n’ihi na ihe karịrị otu nwa na-emepụta AFP
• Nhazi nke oge ruru, n'ihi na ọkwa AFP na-agbanwe n'oge afọ ime

Aha ndị ọzọ: AFP Maternal; Nne nne ọbara AFP; Ihuenyo msAFP

Kedu ihe eji ya?

A na-eji nnwale ọbara nke AFP iji nwa ebu n'afọ na-etolite etolite maka nsogbu nke ọmụmụ na nsogbu mkpụrụ ndụ ihe nketa, dị ka ntụpọ neural tube ma ọ bụ Down syndrome.

Kedu ihe kpatara m ji chọọ nyocha AFP?

Pretù Na-ahụ Maka Uju nke America na-ekwu na a ga-enye ndị inyom nile dị ime nwale ule AFP oge ụfọdụ n’etiti izu nke 15 na nke 20 nke afọ ime. Enwere ike ịkwado ule ahụ karịsịa ma ọ bụrụ na:

• Nwee akụkọ ezinaụlọ gbasara ntụpọ ọmụmụ
• Dị afọ 35 ma ọ bụ karịa
• Nwee ọrịa shuga

Kedu ihe na-eme n'oge ule AFP?

Onye ọkachamara ahụike ga-ewere ihe nyocha ọbara site na akwara aka gị, jiri obere agịga. Mgbe etinyere agịga ahụ, a ga-achịkọta obere ọbara n'ime ule nyocha ma ọ bụ vial. Nwere ike na-eche ntakịrị ihe mgbe agịga na-abanye ma ọ bụ na-apụta. Nke a na-ewe ihe na-erughị nkeji ise.

Ọ dị m mkpa ime ihe ọ bụla iji kwadebe maka ule ahụ?

Kwesighi nkwadebe ọ bụla pụrụ iche maka ule AFP.

Onwere ihe egwu di n’ule a?

Onwere obere ihe egwu diri gi ma obu nwa gi nke anakwere nyocha AFP. May nwere ike ịnwe obere ihe mgbu ma ọ bụ mmerụ ahụ ebe etinyere agịga ahụ, mana ọtụtụ mgbaàmà na-apụ ngwa ngwa. Nnwale ọzọ a na-akpọ amniocentesis na-enye nchoputa ziri ezi nke Down syndrome na ntụpọ ọmụmụ ndị ọzọ, mana nnwale ahụ nwere obere ihe egwu nke ime ọpụpụ.

Kedu ihe nsonaazụ ahụ pụtara?

Ọ bụrụ na nsonaazụ gị gosipụtara ọkwa dị elu karịa ọkwa AFP, ọ nwere ike ịpụta na nwa gị nwere nkwarụ akwara ozi dịka spina bifida, ọnọdụ nke ọkpụkpụ nke ọkpụkpụ azụ adịghị emechi gburugburu eriri afọ, ma ọ bụ anencephaly, ọnọdụ nke ụbụrụ anaghị eto eto nke ọma.

Ọ bụrụ na nsonaazụ gị gosipụtara obere karịa ogo AFP, ọ nwere ike ịpụta na nwa gị nwere nsogbu mkpụrụ ndụ ihe nketa dị ka Down syndrome, ọnọdụ nke na-akpata nsogbu ọgụgụ isi na mmepe.

Ọ bụrụ na ọkwa AFP gị anaghị adịkarị, ọ pụtaghị na enwere nsogbu na nwa gị. Ọ nwere ike ịpụta na ị na-amụ nwa karịa ma ọ bụ na ụbọchị ụbọchị gị ezighi ezi. I nwekwara ike inweta nsonazụ-adighi nma. Nke ahụ pụtara na nsonaazụ gị gosipụtara nsogbu, mana nwa gị gbasiri ike. Ọ bụrụ na nsonaazụ gị gosipụtara ọkwa dị elu karịa nke AFP, ị nwere ike ị nwetakwu ule iji nyere aka chọpụta nchoputa.

Mụtakwuo maka ule nyocha ụlọ, akara ngosi, na nghọta nsonaazụ.

Onwere ihe ozo m choro ima banyere ule AFP?

Ihe nyocha AFP na-abụkarị akụkụ nke usoro nyocha nke ọmụmụ tupu a na-akpọ ọtụtụ akara ngosi ma ọ bụ nyocha ihuenyo atọ. Na mgbakwunye na AFP, nyocha ihuenyo atọ nwere nyocha maka hCG, homonụ nke placenta mepụtara, na estriol, ụdị etrogen nke nwa ebu n'afọ mere. Ule ndị a nwere ike inyere aka chọpụta ọrịa Down na ọrịa mkpụrụ ndụ ihe nketa ndị ọzọ.

Ọ bụrụ n’ị nọ n’ihe ize ndụ karịa ịmụ nwa nwere nsogbu nkwarụ ụfọdụ, onye na-eweta gị nwekwara ike ịkwado nyocha ọhụụ akpọrọ DNA enweghị mkpụrụ ndụ (cfDNA). Nke a bụ nyocha ọbara nke enwere ike ịnye dị ka 10^Nke izu nke afọ ime. Ọ nwere ike igosi nwere ike igosi ma nwa gị ọ nwere ohere dị elu nke ịrịa ọrịa ma ọ bụ ọrịa mkpụrụ ndụ ihe nketa ndị ọzọ.

Ntughari

1. Pretù Ime Ime America [Internet]. Irving (TX): American Ime Ime Association; c2017. Nyocha Nne nwa-Alfa-Fetoprotein (MSAFP) [emelitere 2016 Sep 2; akpọrọ 2017 Jun 5]; [ihe dị ka ihuenyo 3]. E Nweta site na: http://americanpregnancy.org/prenatal-testing/maternal-serum-alpha-fetoprotein-screening
2. Pretù Ime Ime America [Internet]. Irving (TX): American Ime Ime Association; c2017. Ule ihuenyo okpukpu atọ [emelitere 2016 Sep 2; akpọrọ 2017 Jun 5]; [ihe dị ka ihuenyo 3]. E Nweta site na: http://americanpregnancy.org/prenatal-testing/triple-screen-test/
3. Ili JC, Miller KE, Ndị na-ere AD. Nyocha Nne nwa okpukpu atọ na afọ ime. Dọkịta Am Fam [Internet]. 2002 Mar 1 [akpọrọ 2017 Jun 5]; 65 (5): 915–921. E Nweta site na: https://www.aafp.org/afp/2002/0301/p915.html
4. Ọgwụ Johns Hopkins [Internet]. Ọgwụ Johns Hopkins; Librarylọ Ọgwụ Ahụike: Nnwale ndị a na-ahụkarị n'oge Ime Ime [nke e kwuru na 2017 Jun 5]; [ihe dị ka ihuenyo 3]. E Nweta site na: http://www.hopkinsmedicine.org/healthlibrary/condition/adult/pregnancy_and_childbirth/common_tests_during_pregnancy_85,p01241
5. Nnwale ụlọ nyocha na ntanetị [Intanet]. Washington DC: American Association maka Clinical Chemistry; C2001–2019. Nyocha Nne nwa, Nke abụọ ọnwa atọ; [emelitere 2019 Mee 6; akpọrọ 2019 Jun 4]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://labtestsonline.org/tests/maternal-serum-screening-second-trimester
6. Nnwale ụlọ nyocha na ntanetị [Intanet]. American Association maka Clinical Chemistry; C2001–2017. Nkọwa okwu: Spina Bifida [akpọrọ 2017 Jun 5]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://labtestsonline.org/glossary/spina-bifida
7. Merck Manual Consumer Version [Intanet]. Kenilworth (NJ): Merck & Co. Inc.; c2017. Nnyocha nyocha ọhụụ tupu oge ọmụmụ [emelitere 2017 Jun; zoro aka na 2019 June 4]; [ihe dị ka ihuenyo 3]. E Nweta site na: http://www.merckmanuals.com/home/women-s-health-issues/detection-of-genetic-disorders/prenatal-diagnostic-testing
8. Centerlọ Ọrụ Na-ahụ Maka Nkà Mmụta Ntụgharị Asụsụ / /lọ Ọrụ Na-ahụ Maka Ọrịa Ọrịa [Internet]. Gaithersburg (MD): Ngalaba Na-ahụ Maka Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Neural tube ntụpọ [emelitere 2013 Nov 6; akpọrọ 2017 Jun 5]; [ihe dị ka ihuenyo 3]. E Nweta site na: https://rarediseases.info.nih.gov/diseases/4016/neural-tube-defects
9. National Heart, Lung, na Ọbara Institute [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Kedu ihe ize ndụ nke nyocha ọbara? [emelitere 2012 Jan 6; akpọrọ 2017 Jun 5]; [ihe dị ka ihuenyo 5]. Odi site na: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
10. National Heart, Lung, na Ọbara Institute [Internet]. Bethesda (MD): Ngalaba Ahụ Ike na Ọrụ Ndị Ọrụ U.S. Ihe To Ga-atụ Anya Ule Ọbara [emelitere 2012 Jan 6; akpọrọ 2017 Jun 5]; [ihe dị ka ihuenyo 4]. E Nweta site na: https://www.nhlbi.nih.gov/health-topics/blood-tests
11. Mahadum nke Rochester Medical Center [Internet]. Rochester (NY): Mahadum nke Rochester Medical Center; c2017. Health Encyclopedia: Alpha-fetoprotein (AFP) [akpọrọ 2017 Jun 5]; [ihe dị ka ihuenyo 2]. E Nweta site na: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=90&contentid;=P02426
12. Mahadum nke Rochester Medical Center [Internet]. Rochester (NY): Mahadum nke Rochester Medical Center; c2017. Health Encyclopedia: Alpha-fetoprotein (Ọbara) [akpọrọ 2017 Jun 5]; [ihe dị ka ihuenyo 2]. Nweta site na: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=alpha_fetoprotein_maternal_blood
13. Ahụike UW [Internet]. Madison (WI): Mahadum nke Wisconsin italslọọgwụ na Clinics Authority; c2017. Ozi ahụike: Alpha-Fetoprotein (AFP) na Ọbara [emelitere 2016 Jun 30; akpọrọ 2017 Jun 5]; [ihe dị ka ihuenyo 5]. O nwere site na: https://www.uwhealth.org/health/topic/medicaltest/alpha-fetoprotein-afp-in-blood/hw1663.html
14. Ahụike UW [Internet]. Madison (WI): Mahadum nke Wisconsin italslọọgwụ na Clinics Authority; c2017. Ozi Ahụike: Nyocha atọ ma ọ bụ Quad maka mmebi ọmụmụ [emelitere 2016 Jun 30; akpọrọ 2017 Jun 5]; [ihe dị ka ihuenyo 5]. E si na: https://www.uwhealth.org/health/topic/special/maternal-serum-triple-or-quadruple-screening-test/ta7038.html#ta7038-sec

Ejila ozi dị na saịtị a dị ka onye dochie anya nlekọta ahụike ọkachamara ma ọ bụ ndụmọdụ. Kpọtụrụ onye na-ahụ maka ahụike ma ọ bụrụ na ị nwere ajụjụ gbasara ahụike gị.