Nnwale mmamịrị Cortisol

Nnwale mmamịrị cortisol na-atụle ogo cortisol na mamịrị. Cortisol bụ glucocorticoid (steroid) hormone nke adrenal gland mepụtara.

Enwere ike tụọ Cortisol site na iji ọbara ma ọ bụ nyocha mmiri.

A chọrọ mamịrị nke 24 awa. Ikwesiri ichikota mamiri gi ihe kariri awa iri abuo na ano n'ime igbe nke ulo nyocha. Ndị na-ahụ maka ahụike ga-agwa gị otu esi eme nke a. Soro ntuziaka.

Ebe ọ bụ na mmepụta cortisol site na adrenal gland nwere ike ịdị iche, ule ahụ nwere ike ịdị mkpa ime ugboro atọ ma ọ bụ karịa oge dị iche iche iji nweta nkọwa ziri ezi nke mmepụta cortisol.

Enwere ike ịgwa gị ka ị ghara ịmega ahụ ọ bụla ụbọchị ga-ele ule ahụ.

Enwere ike ịgwa gị ka ị kwụsị ị takingụ ọgwụ nke nwere ike imetụta ule ahụ nwa oge, gụnyere:

• Ọgwụ mgbochi iwe
• Estrogen
• Mmadụ mere (sịntetik) glucocorticoids, dị ka hydrocortisone, prednisone na prednisolone
• Androgens

Nnwale ahụ gụnyere urination nkịtị. Enweghị nkasi obi.

Emere ule a iji lelee ma ọ bụ belata nrụpụta cortisol. Cortisol bụ glucocorticoid (steroid) hormone wepụtara site na adrenal gland na nzaghachi na adrenocorticotropic hormone (ACTH). Nke a bụ homonụ nke ewepụtara na pituitary gland na ụbụrụ. Cortisol na-emetụta ọtụtụ usoro ahụ dị iche iche. Ọ na-ekere òkè na:

• Ọkpụkpụ uto
• Ọbara mgbali elu
• Dịghịzi usoro ọrụ
• Metabolism nke abụba, carbohydrates, na protein
• Systemjọ usoro ọrụ
• Nzaghachi nchegbu

Ọrịa dị iche iche, dị ka ọrịa Cushing na ọrịa Addison, nwere ike ibute ma ọ bụ mepụta nke cortisol nke ukwuu ma ọ bụ nke pere mpe. Urinetụ ọkwa ọkwa cortisol mmamịrị nwere ike inyere gị aka ịchọpụta ọnọdụ ndị a.

Nkịtị dị bụ 4 ka 40 mcg / 24 awa ma ọ bụ 11 ruo 110 nmol / ụbọchị.

Usoro ntanetị dị iche iche nwere ike ịdịtụ iche n'etiti ụlọ nyocha dị iche iche. Lafọdụ labs na-eji nha dị iche iche ma ọ bụ nwee ike ịnwale ụdị dị iche iche. Gwa onye na - enye gị ọrụ gbasara ihe nyocha gị pụtara.

Ọkwa dị elu karịa ọkwa nkịtị nwere ike igosi:

• Ọrịa Cushing, nke pituitary gland na-eme ACTH nke ukwuu n'ihi uto nke pituitary gland ma ọ bụ akpụ dị na ya na pituitary gland.
• Ectopic Cushing syndrome, nke etuto dị n'èzí pituitary ma ọ bụ adrenal glands na-eme nnukwu ACTH
• Oké ịda mbà n'obi
• Tumor nke adrenal gland na-emepụta oke cortisol
• Nnukwu nrụgide
• Ọrịa mkpụrụ ndụ na-adịghị ahụkebe

A ala karịa nkịtị larịị nwere ike na-egosi:

• Ọrịa Addison nke gland adrenal anaghị emepụta cortisol zuru ezu
• Hypopituitarism nke pituitary gland anaghị egosi gland iji mepụta cortisol zuru oke
• Mwepu nke pituitary ma ọ bụ ọrụ adrenal site na ọgwụ glucocorticoid gụnyere mkpụrụ ọgwụ, ude anụ ahụ, eyedrops, ndị na-ekpo ọkụ, nkwonkwo nkwonkwo, chemotherapy

Enweghị nsogbu dị na ule a.

24-hour urinary free cortisol (UFC)

• Nwanyi urinary tract
• Nwoke urinary tract

Chernecky CC, Berger BJ. Cortisol - mmamịrị. Na: Chernecky CC, Berger BJ, eds. Nnwale Laboratory na Usoro Nyocha. Nke isii. St Louis, MO: Elsevier Saunders; 2013: 389-390.

Stewart PM, Newell-Ahịa JDC. Na adrenal cortex. Na: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Akwụkwọ ọgụgụ Williams nke Endocrinology. Nke 13. Philadelphia, PA: Elsevier; 2016: isi 15.