Ọrịa Dermatomyositis

Dermatomyositis bụ ọrịa anụ ahụ nke metụtara mbufụt na anụ ahụ ọkụ. Polymyositis bụ ọnọdụ mkpali yiri nke ahụ, nke na-agụnyekwa adịghị ike akwara, ọzịza, ịdị nro, na mmebi anụ ahụ mana enweghị akpụkpọ anụ. Ha abụọ bụ akụkụ nke nnukwu ọrịa nke a na-akpọ myopathy inflammatory.

Ihe kpatara dermatomyositis amaghị. Ndị ọkachamara na-eche na ọ nwere ike ịbụ n'ihi ọrịa nje nke akwara ma ọ bụ nsogbu na usoro ahụ ji alụso ọrịa ọgụ. Ọ nwekwara ike ịpụta na ndị nwere kansa na afọ, ngụgụ, ma ọ bụ akụkụ ndị ọzọ nke ahụ.

Onye ọ bụla nwere ike ịmalite ọrịa a. Ọ na-apụtakarị na ụmụaka dị afọ 5 ruo 15 na ndị okenye dị afọ 40 ruo 60. Ọ na-emetụta ụmụ nwanyị karịa ụmụ nwoke.

Mgbaàmà nwere ike ịgụnye:

• Ike adịghị ike, isi ike, ma ọ bụ ọnya
• Nsogbu ilo
• Acha odo odo na nku anya elu
• Acha ọkụ-acha ọbara ọbara
• Iku ume ọkụ ọkụ

Adịghị ike akwara nwere ike ịbịa na mberede ma ọ bụ jiri nwayọ nwayọ karịa izu ma ọ bụ ọnwa. May nwere ike nwee nsogbu bulie aka gị n’isi, bilie ọtọ, ma rịgoro steepụ.

Ọrịa nwere ike ịpụta na ihu gị, nkwonkwo nkwonkwo, olu, ubu, obi elu, na azụ.

Onye nlekọta ahụike ga-eme nyocha anụ ahụ. Ule nwere ike ịgụnye:

• Ọbara na-anwale ogo ogo enzymes muscle akpọrọ creatine phosphokinase na aldolase
• Nyocha ọbara maka ọrịa autoimmune
• ECG
• Ihe omuma (EMG)
• Ihe ntanetị na-eme magnet (MRI)
• Nnukwu biopsy
• Skin biopsy
• Nyocha nyocha ndị ọzọ maka kansa
• Igwe ọkụ na CT nyocha nke igbe
• Ume ọrụ ule
• Na-eloda ọmụmụ
• Myositis akọwapụtara na autoantibodies metụtara

Isi ọgwụgwọ bụ iji ọgwụ corticosteroid. A na-eji nwayọọ nwayọọ etinye ọgwụ dị ka ike ahụ ike. Nke a na-ewe ihe dị ka izu anọ na isii. Nwere ike ịnọ na obere ọgwụ nke corticosteroid ọgwụ mgbe nke ahụ gasịrị.

Enwere ike iji ọgwụ iji gbochie usoro ahụ jijiji iji dochie corticosteroids. Ọgwụ ndị a nwere ike ịgụnye azathioprine, methotrexate ma ọ bụ mycophenolate.

Ọgwụ ndị enwere ike ịnwale mgbe ọrịa na-adịgide adịgide n'agbanyeghị ọgwụ ndị a bụ:

• Igba ogwu gamma globulin
• Ọgwụ ndu ogwu

Mgbe akwara gị siri ike, onye na-eweta gị nwere ike ịgwa gị ka ị jiri nwayọ belata usoro gị. Ọtụtụ ndị mmadụ nwere ụdị ọrịa a ga-a takeụ ọgwụ a na-akpọ prednisone n’oge ndụ ha niile.

Ọ bụrụ na ọrịa kansa na-akpata ọnọdụ ahụ, adịghị ike akwara na ọkụ ọkụ nwere ike ịka mma mgbe ewepụrụ akpụ.

Mgbaàmà nwere ike ịpụ kpamkpam na ụfọdụ ndị, dị ka ụmụaka.

Ọnọdụ ahụ nwere ike ịnwụ na ndị okenye n'ihi:

• Nnukwu ike adịghị ike
• Erighị nri na-edozi ahụ
• Ọrịa oyi
• Lung ọdịda

Isi ihe kpatara ọnwụ na ọnọdụ a bụ ọrịa kansa na ọrịa akpa ume.

Ndị nwere ọrịa akpa ume na mgbochi MDA-5 antibody nwere amụma na-adịghị mma n'agbanyeghị ọgwụgwọ ugbu a.

Nsogbu nwere ike ịgụnye:

• Ọrịa akpa ume
• Nnukwu akụrụ odida
• Cancer (malignancy)
• Mbufụt nke obi
• Nkwonkwo mgbu

Kpọọ onye na-eweta gị ma ọ bụrụ na ị nwere adịghị ike mọzụlụ ma ọ bụ mgbaàmà ndị ọzọ nke ọnọdụ a.

• Dermatomyositis - Gottron papule
• Dermatomyositis - Gottron papules n’aka
• Dermatomyositis - nku anya nke heliotrope
• Dermatomyositis na ụkwụ
• Dermatomyositis - Gottron papule
• Paronychia - onye obula
• Dermatomyositis - heliotrope ọkụ na ihu

Aggarwal R, Rider LG, Ruperto N, et al. 2016 American College of Rheumatology / European League Against Rheumatism Criteria for Minimal, Moderate, and Major Clinical Response in Adult Dermatomyositis and Polymyositis: Otu International Myositis Assessment and Clinical Studies Group / Pediatric Rheumatology International Trials Organisation Collaborative Initiative. Ogbu na nkwonkwo Rheumatol. Ọrịa. 2017; 69 (5): 898-910. PMID: 28382787 www.ncbi.nlm.nih.gov/pubmed/28382787.

Dalakas MC. Ọrịa akwara inflammatory. N Engl J Ahụike. 2015; 373 (4): 393-394. PMID: 26200989 www.ncbi.nlm.nih.gov/pubmed/26200989.

Nagaraju K, Gladue HS, Lundberg IE. Ọrịa inflammatory nke akwara na myopathies ndị ọzọ. Na: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Akwụkwọ Kelley na Firestein nke Rheumatology. Nke iri. Philadelphia, PA: Elsevier; 2017: isi 85.

Organizationtù Na-ahụ Maka Ọrịa Na-ahụ Maka Ahụhụ na weebụsaịtị. Ọrịa Dermatomyositis. rarediseases.org/rare-diseases/dermatomyositis/. Nabata April 1, 2019.