Ọrịa imeju - hepatocellular carcinoma

Hepatocellular carcinoma bụ ọrịa kansa na-amalite n'ime umeji.

Hepatocellular carcinoma na-ede ọtụtụ ọrịa cancer. Typedị kansa a na-abịakarị na ụmụ nwoke karịa ụmụ nwanyị. A na-achọpụtakarị ya na ndị dị afọ 50 ma ọ bụ karịa.

Ọrịa hepatocellular abụghị otu ihe dị ka ọrịa cancer imeju metastatic, nke na-amalite na akụkụ ọzọ (dịka ara ma ọ bụ eriri afọ) wee gbasaa na imeju.

N'ọtụtụ ọnọdụ, ihe kpatara ọrịa cancer nke imeju bụ mbibi na-adịte aka na ọnya imeju (cirrhosis). Cirrhosis nwere ike kpatara:

• Abuse abuseụbiga mmanya ókè
• Ọrịa autoimmune nke imeju
• Patba ọcha n'anya B ma ọ bụ ịba ọcha n'anya C nje ọrịa
• Mbufụt nke imeju nke dị ogologo oge (ala ala)
• Iron bufee na ahụ (hemochromatosis)

Ndị nwere ịba ọcha n'anya nke B ma ọ bụ C nọ n'oké ihe ize ndụ nke kansa cancer, ọ bụrụgodị na ha anaghị emepụta ọrịa cirrhosis.

Mgbaàmà nke kansa cancer nwere ike ịgụnye nke ọ bụla n'ime ihe ndị a:

• Ime mgbu ma ọ bụ nro, karịsịa na akụkụ aka nri-elu
• Mgbu ma ọ bụ ọbara ọgbụgba dị mfe
• Abdomenba afọ (ascites)
• Agba odo ma ọ bụ anya (jaundice)
• Ọnwụ ọnwụ a na-akọwaghị

Onye nlekọta ahụike ga-eme nyocha anụ ahụ ma jụọ maka ihe mgbaàmà gị. Nnwale ahụ pụrụ igosipụta imeju, imeju obi ma ọ bụ ihe ịrịba ama ndị ọzọ nke cirrhosis.

Ọ bụrụ na onye ọrụ ahụ na-enyo enyo na-arịa ọrịa imeju, nyocha ndị nwere ike ịnye iwu gụnyere:

• Ime CT i scanomi
• Nyocha MRI nke afọ
• Ime ultrasound
• Ọkpụkpụ imeju
• Nnwale ọrụ imeju
• Ọbara alpha fetoprotein

Fọdụ ndị nwere nnukwu ohere nke ịrịa ọrịa kansa imeju nwere ike ịnwale ule ọbara na ultrasound mgbe niile iji hụ ma etuto etolite.

Iji chọpụta ọrịa carpoma hepatocellular n'ụzọ ziri ezi, a ghaghị ime biopsy nke etuto ahụ.

Ọgwụgwọ dabere n’etu ogo kansa a.

Enwere ike ịwa ahụ ma ọ bụrụ na etuto ahụ agbasaghị. Tupu ịwa ahụ, enwere ike ịgwọ etuto ahụ na ọgwụ iji belata nha ya. A na-eme ya site n'iwepu ọgwụ ahụ n'ime imeju ahụ na tube (catheter) ma ọ bụ site n'inye ya nsị (site na IV).

Ọgwụ radieshọn n'akụkụ mpaghara kansa ahụ nwekwara ike inye aka.

Ablation bụ usoro ọzọ enwere ike iji. Ablate pụtara nbibi. Abdị nke nsonye gụnyere iji:

• Redio ebili mmiri ma ọ bụ microwaves
• Ethanol (mmanya) ma ọ bụ acetic acid (mmanya)
• Oke oyi (mkpu)

Enwere ike ịkwado imeju umeji.

Ọ bụrụ na enweghi ike ịwa ahụ cancer ma ọ bụ gbasaa na mpụga imeju, enweghị ohere ọ bụla maka ọgwụgwọ ogologo oge. Ọgwụgwọ na-elekwasị anya na ịkwalite na ịgbatịkwu ndụ onye ahụ. Ọgwụgwọ na nke a nwere ike iji ọgwụgwọ ezubere iche na ọgwụ ndị enwere ike iwere dị ka ọgwụ. A pụkwara iji ọgwụ mgbochi ọrịa ọhụụ.

Nwere ike belata nchekasị nke ọrịa site na isonyere ndị otu na-akwado ọrịa kansa. Kọrọ ndị ọzọ ihe ha na-eme na nsogbu niile nwere ike inyere gị aka ichewe naanị gị.

Ọ bụrụ na enweghi ike ịgwọ ọrịa cancer kpamkpam, ọrịa a na-abụkarị ọnwụ. Mana nlanarị nwere ike ịdị iche, dabere n’etu kansa a siri dị elu ma a chọpụta ya yana etu usoro ọgwụgwọ si aga nke ọma.

Kpọọ onye na-eweta gị ma ọ bụrụ na ị mepụta ihe mgbu afọ na-aga n'ihu, ọkachasị ma ọ bụrụ na ị nwere akụkọ ihe mere eme nke ọrịa imeju.

Mgbochi na-agụnye:

• Igbochi na ịgwọ ịba ọcha n'anya nke nje nwere ike inye aka belata ihe egwu gị. Vaccingba ọgwụ mgbochi ụmụaka maka ịba ọcha n'anya B nwere ike belata ohere nke ọrịa kansa imeju n'ọdịnihu.
• A drinkụla mmanya na-aba n'anya.
• Ọ nwere ike ịdị mkpa ka enyocha ndị nwere ụdị hemochromatosis (iron overload) maka ọrịa cancer umeji.
• Enwere ike ịkwado ndị nwere ịba ọcha n'anya B ma ọ bụ C ma ọ bụ cirrhosis maka nyocha ọrịa cancer umeji.

Carcinoma cell nke imeju nke mbu; Tumo - imeju; Ọrịa cancer - imeju; Patba ọcha n'anya

• Usoro nri
• Ọkpụkpụ imeju
• Hepatocellular cancer - CT nyocha

Abou-Alfa GK, Jarnagin W, Dika IE, et al. Imeju na bile duct cancer. Na: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff’s Clinical Oncology. Nke isii. Philadelphia, PA: Elsevier; 2020: isi 77.

Di Bisceglie AM, Befeler AS. Hepatic etuto ahụ na akpịrị. Na: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger na Ọrịa Cancer nke Fordtran na Ọrịa Imeju: Pathophysiology / Diagnosis / Management. Nke iri. Philadelphia, PA: Elsevier Saunders; 2016: isi 96.

Weebụsaịtị National Cancer Institute. Okenye isi ịgwọ ọrịa imeju (PDQ) - ụdị ọkachamara ahụike. www.cancer.gov/types/liver/hp/adult-liver-treatment-pdq. Emelitere March 24, 2019. Nabata August 27, 2019.

National Comprehensive Cancer Network weebụsaịtị. NCCN usoro nlekọta ahụike na oncology: ọrịa cancer hepatobiliary. Dị 3.2019. www.nccn.org/professionals/physician_gls/pdf/hepatobiliary.pdf. Emelitere August 1, 2019. Nabata August 27, 2019.