Kedu ihe bụ hemoglobin glycated, gịnị ka ọ bụ maka ya na ụkpụrụ nrụtụ aka

Ndinaya

• Kedu ihe bụ hemoglobin glycated maka
• Ihe njirimara

Glycated hemoglobin, nke a makwaara dị ka haemoglobin glycosylated ma ọ bụ Hb1Ac, bụ nyocha ọbara nke na-achọ ịlele ogo glucose n'ime ọnwa atọ gara aga tupu e mee nyocha ahụ. Nke ahụ bụ n'ihi na glucose nwere ike ịrapara na otu n'ime ihe mejupụtara sel ọbara uhie, haemoglobin, n'ime usoro mkpụrụ ndụ ọbara uhie, nke na-ewe ihe dị ka ụbọchị 120.

Ya mere, dọkịta ahụ na-arịọ nyocha nke hemoglobin glycated iji chọpụta ọrịa shuga, nyochaa mmepe ya ma ọ bụ chọpụta ma ọgwụgwọ nke ọrịa ahụ ọ dị irè, a na-eme site na nyocha nke obere ọbara nke anakọtara na laabu.

Kedu ihe bụ hemoglobin glycated maka

A na-eme nnyocha banyere haemoglobin a na-emepụta glycated iji mee ka ọ̀tụ̀tụ̀ glucose dị n'ọtụtụ ọnwa ndị na-adịbeghị anya, bụrụ ihe bara uru n'ịchọpụta ọrịa shuga. Na mgbakwunye, n'ihe banyere ndị mmadụ achọpụtala na ha nwere ọrịa shuga, ule a bara uru iji chọpụta ma ọgwụgwọ ahụ ọ na-arụ ọrụ ka ọ bụ na a na-eme ya n'ụzọ ziri ezi, n'ihi na ọ bụrụ na ọ bụghị, enwere ike nyochaa mgbanwe nsonaazụ ya.

Tụkwasị na nke a, mgbe uru nke hemoglobin glycated dị nnọọ elu karịa nke ndị ụlọ nyocha na-atụle, ọ ga-akacha mma ka onye ahụ nwee nsogbu ndị metụtara ọrịa shuga, dịka ọmụmaatụ obi, mgbatị ma ọ bụ ngbanwe neuronal, dịka ọmụmaatụ. Hụ ihe bụ isi nsogbu nke ọrịa shuga.

Ule a dị mma karịa glucose na-ebu ọnụ maka nchọpụta mbụ nke ọrịa shuga, n'ihi na mgbanwe nke ụdị nri na-adịbeghị anya nwere ike imetụta ule glucose, ọ bụghị na-anọchite anya ọkwa shuga na-ekesa na ọnwa ole na ole gara aga. Ya mere, ọ ga - ekwe omume na tupu ị mee nyocha glucose, onye ahụ nwere nri ahụike na shuga dị ala, nke mere na glucose na - ebu ọnụ nwere ike ịdị n'ime ụkpụrụ nkịtị, nke nwere ike ọ gaghị anọchite anya onye ahụ.

Ya mere, iji mee nchoputa nke ọrịa shuga, a na-arịọkarị nyocha nke glucose ngwa ngwa, hemoglobin glycated na / ma ọ bụ ule nnabata glucose, TOTG. Mụtakwuo banyere ule ndị na-enyere aka ịchọpụta ọrịa shuga.

Ihe njirimara

Ihe ntụgharị maka hemoglobin glycated nwere ike ịdị iche na laabu, mana n'ozuzu ụkpụrụ ndị a tụlere bụ:

• Nkịtị: Hb1Ac n'etiti 4.7% na 5.6%;
• Tupu ọrịa shuga: Hb1Ac n'etiti 5.7% na 6.4%;
• Ọrịa shuga: Hb1Ac n'elu 6.5% na ule abụọ emere iche iche.

Na mgbakwunye, n'ime ndị mmadụ achọpụtala n'ọrịa shuga, ụkpụrụ Hb1Ac n'etiti 6.5% na 7.0% na-egosi na enwere njikwa ọrịa nke ọma. N'aka nke ọzọ, ụkpụrụ dị elu karịa Hb1Ac karịa 8% na-egosi na anaghị achịkwa ọrịa shuga n'ụzọ ziri ezi, yana nnukwu nsogbu nke nsogbu yana mgbanwe ọgwụgwọ dị mkpa.

Glymosis hemoglobin anaghị achọ nkwadebe ọ bụla, agbanyeghị, dịka a na-achọkarị ya na ule glucose bu ọnụ, ọ nwere ike ịdị mkpa iji ọnụ maka opekempe 8 awa.