Sideroblastic anaemia: ihe ọ bụ, mgbaàmà, ihe na-akpata na ọgwụgwọ

Ndinaya

• Ihe nwere ike ibute ya
• Isi mgbaàmà
• Kedu ka esi eme nchoputa
• Otu esi eme ọgwụgwọ ahụ

A na-ahụkarị anemia sideroblastic site na iji iron eme ihe na-ekwesịghị ekwesị maka njikọ nke hemoglobin, nke na-eme ka ígwè na-agbakọta n'ime mitochondria nke erythroblasts, na-eme ka mgbanaka sideroblasts, nke a na-ahụ anya na nyocha nke ọbara n'okpuru microscope.

Nsogbu a nwere ike jikọta ya na ihe nketa, ihe enwetara ma ọ bụ n'ihi myelodysplasias, na-eduga na ndapụta nke mgbaàmà ejiri mara anaemia, dị ka ike ọgwụgwụ, pallor, dizziness and adịghị ike.

Ọgwụgwọ dabere na oke ọrịa ahụ, yana folic acid na vitamin B6 na-achịkwa ya n'ozuzu yana n'ọnọdụ ndị siri ike karị, ọ nwere ike ịdị mkpa iji megharia ụmị ọkpụkpụ.

Ihe nwere ike ibute ya

Sideroblastic anaemia nwere ike bụrụ ihe ebumpụta ụwa, nke bụ mgbe a mụrụ mmadụ na nsogbu ahụ, ma ọ bụ nweta ya, nke sideroblasts na-apụta dị ka ọnọdụ nke ọnọdụ ndị ọzọ. N'ihe banyere anaemia sideroblastic congenital, ọ kwekọrọ na mgbanwe mkpụrụ ndụ ihe nketa, jikọtara ya na X chromosome, nke, n'ihi ngbanwe, na-akwalite mgbanwe na metabolism mitochondrial, na-ebute mmepe nke ụdị anaemia a.

N'ihe banyere anemia a na-enweta n'akụkụ, isi ihe kpatara ya bụ ọrịa myelodysplastic, nke kwekọrọ na otu ọrịa nke enwere ụmị ọkpụkpụ na-aga n'ihu na-ebute mmepụta nke mkpụrụ ndụ ọbara akaghi aka. Ihe ndị ọzọ nwere ike ịkpata anaemia sideroblastic bụ:

• A alcoholụrụma na-adịghị ala ala;
• Ọrịa ogbu ogbu na nkwonkwo;
• Ngosipụta na nsị;
• Enweghi vitamin B6 ma ọ bụ ọla kọpa;
• Iji ụfọdụ ọgwụ, dị ka chloramphenicol na isoniazid;
• Ọrịa autoimmune.

Na mgbakwunye, ụdị anemia a nwere ike ịbụ nsonaazụ nke mgbanwe ọbara ndị ọzọ na ụmị ọkpụkpụ, dịka myeloma, polycythemia, myelosclerosis na leukemia.

Isi mgbaàmà

A na-egosipụta ihe mgbaàmà nke ọtụtụ ọrịa nke anemia ndị a na-eketa site na nwata, agbanyeghị, enwere ike ịnwe ọnọdụ dị ala karị nke anaemia sideroblastic ana-eketa bụ ndị mgbaàmà ya na-apụta ihe n'oge okenye.

N'ozuzu, ihe mgbaàmà nke anaemia sideroblastic bụ otu ihe dị ka nke anaemia nkịtị, nke onye ahụ nwere ike ịnweta ike ọgwụgwụ, ike belata ikike ịme ahụ, dizziness, adịghị ike, tachycardia na pallor, na mgbakwunye na ịbụ ndị na-adịkarị mfe ọbara na ọrịa.

Iji chọpụta ihe ize ndụ nke ịnwe anemia, họrọ akara ngosi ị nwere ike ịnwe n'okpuru:

1. 1. Enweghị ume na oke ike ọgwụgwụ
2. 2. Icha akpụkpọ
3. 3. Enweghị njikere na arụpụtaghị ihe dị ala
4. 4. Isi ọwụwa mgbe niile
5. 5. Mgbakasị dị mfe
6. 6. Agụụ a na-apụghị ịkọwa akọwa ya iri ihe dị iche dịka brik ma ọ bụ ụrọ
7. 7. Icheta ncheta ma ọ bụ nsogbu itinye uche

Kedu ka esi eme nchoputa

Nchọpụta nke ọrịa ana-akpọ sideroblastic kwesịrị ime site na hematologist ma ọ bụ onye ọkachamara n'ozuzu site na nyochaa ihe ịrịba ama na mgbaàmà gosipụtara site na nke nwere ike ime na ịme ọnụọgụ ọbara nke enwere ike ịlele erythrocytes nwere ụdị dị iche iche na ụfọdụ n'ime ha nwere ike ịpụta. Tụkwasị na nke a, a na-arụkwa ọnụ ọgụgụ reticulocyte, nke bụ mkpụrụ ndụ ọbara uhie akaghi aka, nke na-adịkarị n'ụdị anaemia a.

Dọkịta na-egosi nha iron, ferritin na transferrin saturation nke dọkịta, dịka ha nwekwara ike gbanwee na anemia sideroblastic. N'ọnọdụ ụfọdụ, dọkịta ahụ nwekwara ike ịkwado ịme ule iji nyochaa ụmị ọkpụkpụ, dịka na mgbakwunye na inye aka iji kwado anaemia sideroblastic, ọ na-enye aka ịchọpụta ihe kpatara mgbanwe ahụ.

Otu esi eme ọgwụgwọ ahụ

Ekwesiri ime ọgwụgwọ maka anaemia sideroblastic dịka ntụpọ nke dọkịta na ihe kpatara anaemia, yana mgbakwunye na vitamin B6 na folic acid nwere ike igosi, na mgbakwunye na mbenata oriri nke mmanya na-aba n'anya. Ọ bụrụ na anaemia bụ n'ihi iji ọgwụ, enwere ike igosipụta nkwụsịtụ ojiji ya.

N'okwu ndị kachasị njọ, bụ nke anaemia bụ nsonaazụ nke mgbanwe na arụ ọrụ nke ụmị ọkpụkpụ, dọkịta nwere ike igosi transplantation nke transplantation. Ghọta otua si eme ụmị ọkpụkpụ.