Neurosyphilis

Neurosyphilis bụ ọrịa nje nke ụbụrụ na ụbụrụ ma ọ bụ ọgidigi azụ. Ọ na - apụtakarị na ndị mmadụ enwetabeghị ọgwụgwọ syphilis ruo ọtụtụ afọ.

Neurosyphilis na-akpata Treponema pallidum. Nke a bụ nje na-akpata syphilis. Neurosyphilis na-apụtakarị ihe dị ka afọ 10 ruo 20 mgbe mmadụ butere ọrịa syphilis na nke mbụ ya. Ọ bụghị onye ọ bụla nwere syphilis na-amalite nsogbu a.

E nwere ụdị neurosyphilis anọ dị iche iche:

• Asymptomatic (ụdị kachasịkarị)
• General paresis
• Meningovascular
• Tabes dorsalis

Asymptomatic neurosyphilis pụtara tupu symplis symptomatic. Asymptomatic pụtara na ọ dịghị ihe mgbaàmà ọ bụla.

Mgbaàmà na-emetụtakarị ụjọ usoro. Dabere n'ụdị nke neurosyphilis, ihe mgbaàmà nwere ike ịgụnye nke ọ bụla n'ime ihe ndị a:

• Ọdịdị na-adịghị mma (gait), ma ọ bụ enweghị ike ịga ije
• Ọnụ ọgụgụ na mkpịsị ụkwụ, ụkwụ, ma ọ bụ ụkwụ
• Nsogbu dị iche iche, dị ka mgbagwoju anya ma ọ bụ itinye uche n'ihe
• Nsogbu uche, dị ka ịda mbà n'obi ma ọ bụ mgbakasị
• Isi ọwụwa, ọdịdọ, ma ọ bụ olu olu
• Loss nke eriri afo akara (incontinence)
• Majiji, ma ọ bụ adịghị ike
• Nsogbu anya, ma ìsì

Onye nlekọta ahụike gị ga-eme nyocha ahụ wee nwee ike ịchọta ihe ndị a:

• Ndị na-eme mgbanwe
• Atrophy akwara
• Mgbu akwara
• Mgbanwe echiche

Enwere ike ime ule ọbara ịchọpụta ihe ndị nje bacteria na - akpata nke na - eme ka syphilis mepụta, nke a gụnyere:

• Treponema pallidum urughuru agglutination nnwale (TPPA)
• Nnyocha ụlọ nyocha ọrịa ọrịa Venereal (VDRL) ule
• Fluorescent treponemal antibody absorption (FTA-ABS)
• Reagin plasma ngwa ngwa (RPR)

Na neurosyphilis, ọ dị mkpa iji nwalee mmiri ọgwụ maka ihe ịrịba ama nke syphilis.

Ule ịchọ nsogbu maka usoro ụjọ nwere ike ịgụnye:

• Ọrịa ụbụrụ angiogram
• Isi CT i .omi
• Mgbapu Lumbar (ọkpụkpụ azụ) na mkpụrụ ndụ cerebrospinal ọmụmụ (CSF)
• Nnyocha MRI nke ụbụrụ, ụbụrụ, ma ọ bụ ụbụrụ

A na-eji ọgwụ nje penicillin agwọ neurosyphilis. Enwere ike inye ya n'ụzọ dị iche iche:

• Itinye n'ime akwara ọtụtụ ugboro n'ụbọchị maka ụbọchị iri na anọ ruo ụbọchị iri na anọ.
• Site n’ọnụ 4 ugboro n’ụbọchị, tinyere ọgwụ injeeji kwa ụbọchị, e were ha were ụbọchị iri rue ụbọchị iri na anọ.

Ga-enwerịrị nyocha ọbara na ọnwa 3, 6, 12, 24, na 36 iji hụ na ọrịa ahụ apụla. Ga-achọ punctures na-esochi lumbar maka nyocha CSF kwa ọnwa 6. Ọ bụrụ na ị nwere HIV / AIDS ma ọ bụ ọnọdụ ahụike ọzọ, usoro ịgbaso gị nwere ike ịdị iche.

Neurosyphilis bụ nsogbu na-eyi ndụ egwu nke syphilis. Etu ị si eme nke ọma dabere na etu neurosyphilis siri sie ike tupu ọgwụgwọ. Ebumnuche nke ọgwụgwọ bụ iji gbochie nsogbu ka njọ. Ọtụtụ n'ime mgbanwe ndị a anaghị agbanwe agbanwe.

Ihe mgbaàmà ahụ nwere ike iji nwayọọ nwayọọ na-akawanye njọ.

Kpọọ onye na-eweta gị ma ọ bụrụ na ịnwee syphilis n'oge gara aga ma ugbu a nwee akara nke nsogbu sistemụ ụjọ.

Ngwa ngwa nchoputa na ọgwụgwọ nke mbụ syphilis ọrịa nwere ike igbochi neurosyphilis.

Syphilis - neurosyphilis

• Usoro nhụjuanya nke etiti na usoro ụjọ nke elu
• Ikpeazụ-wara wara

Euerle BD. Ọkpụkpụ azụ na nyocha mmiri nke cerebrospinal. Na: Roberts JR, Custalow CB, Thomsen TW, eds. Usoro ọgwụgwọ Clinical nke Roberts na Hedges na Medicine Mberede na Nnukwu Nlekọta. Nke 7. Philadelphia, PA: Elsevier; 2019: isi 60.

National Institute of Neurological Disorders na ebe nrụọrụ weebụ strok. Neurosyphilis. www.ninds.nih.gov/Disorders/All-Disorders/Neurosyphilis-Information-Page. Emelitere March 27, 2019. Nabata February 19, 2021.

Radolf JD, Tramont EC, Salazar JC. Syphilis (Treponema pallidum). Na: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, na Bennett Prinkpụrụ na Omume nke Ọrịa Na-efe Ọrịa. Agba nke 9. Philadelphia, PA: Elsevier; 2020: isi 237.