Otutu myeloma

Otutu myeloma bu oria obara nke na amalite na sel plasma di na okpukpu. Ọkpụkpụ bụ anụ ahụ dị nro, nke na-eme ka ọ dị n’ime ọtụtụ ọkpụkpụ. Ọ na - enyere aka mee sel ọbara.

Mkpụrụ ndụ Plasma na - enyere ahụ gị aka ịlụso ọrịa ọgụ site na ịmị protein dị iche iche. Na ọtụtụ myeloma, mkpụrụ ndụ plasma na-eto eto na ụmị ọkpụkpụ ma mepụta etuto dị n'akụkụ ọkpụkpụ siri ike. Uto nke etuto ndị a na-eme ka ọkpụkpụ ahụ sie ike. Ọ na-emekwa ka o sie ike maka ụmị ọkpụkpụ iji mee ka mkpụrụ ndụ ọbara na platelet dị mma.

Ihe kpatara otutu myeloma amaghi. Ọgwụgwọ oge gara aga na ọgwụgwọ radieshon na-abawanye ohere maka ụdị kansa a. Otutu myeloma na emetuta ndi okenye.

Otutu myeloma na-akpatakarị:

• Obere ọbara ọbara uhie (anaemia), nke nwere ike ibute ike ọgwụgwụ na iku ume
• Obere ọbara ọbara ọcha, nke na - eme ka ị nwee ike ibute ọrịa
• Obere platelet, nke nwere ike ibute ọbara ọgbụgba na-adịghị mma

Dị ka mkpụrụ ndụ cancer na-eto na ụmị ọkpụkpụ, ị nwere ike ịnwe ụfụ ọkpụkpụ, ọtụtụ oge ọgịrịga ma ọ bụ azụ.

Mkpụrụ ndụ cancer nwere ike ime ka ọkpụkpụ daa mbà. N'ihi ya:

• Nwere ike ịmalite ọkpụkpụ gbajiri agbaji (ọkpụkpụ ọkpụkpụ) naanị site na ịme ọrụ nkịtị.
• Ọ bụrụ na ọrịa kansa na-eto n'ọkpụkpụ azụ, ọ nwere ike pịa akwara. Nke a nwere ike iduga na ọgbụgba ma ọ bụ adịghị ike nke ogwe aka ma ọ bụ ụkwụ.

Onye nlekọta ahụike ga-eme nyocha anụ ahụ ma jụọ maka ihe mgbaàmà gị.

Nyocha ọbara nwere ike inye aka chọpụta ọrịa a. Ule ndị a gụnyere:

• Albumin larịị
• Calcium larịị
• Mkpokọta protein larịị
• Akụrụ ọrụ
• Ọnụọgụ ọbara zuru ezu (CBC)
• Immunofixation
• Ọnụọgụ ọnụọgụ
• Ọbara protein electrophoresis

Ọkpụkpụ x-ụzarị, nyocha CT, ma ọ bụ MRI nwere ike igosi mgbawa ma ọ bụ oghere nke ọkpụkpụ. Ọ bụrụ na onye na-eweta gị na-enyo ụdị ọrịa kansa a, a ga-eme biopsy ụmị ọkpụkpụ.

Ọkpụkpụ njupụta nke ule nwere ike igosi ọkpụkpụ ọkpụkpụ.

Ọ bụrụ na nyocha egosi na ị nwere ọtụtụ myeloma, a ga-eme nyocha ọzọ iji hụ ókè ọrịa kansa ahụ si gbasaa. A na-akpọ nke a staging. Ihe nlere na enyere aka iduzi ọgwụgwọ na ntinye.

A na-enyochakarị ndị nwere ọrịa pere mpe ma ọ bụ onye onye ahụ amaghị na nyocha ya. Fọdụ ndị mmadụ nwere ụdị nke ọtụtụ myeloma nke na - eto nwayọ nwayọ (na - ere anwụrụ), nke na - ewe ọtụtụ afọ iji bute ihe mgbaàmà.

A na-eji ụdị ọgwụ dị iche iche agwọ ọtụtụ myeloma. A na-enyekarị ha iji gbochie nsogbu dịka mgbaji ọkpụkpụ na mmebi akụrụ.

Enwere ike iji ọgwụgwọ radieshon mee ka ihe mgbu ọkpụkpụ belata ma ọ bụ belata nsị nke na-agba na ọkpụkpụ azụ.

Enwere ike ịkwado ụmị ọkpụkpụ:

• A na - eji ụm ụ s ụ nke mmadụ mee ihe na - eme ka ụm ụ ọkpụkpụ ma ọ bụ sel sel ga - eme onwe ya.
• Ntughari allogeneic na-eji sel nke onye ozo. Usoro ọgwụgwọ a nwere nnukwu ihe egwu, mana ọ nwere ike ịnye mmadụ ohere ịgwọ ya.

Gị na onye na-eweta gị nwere ike jikwaa nchegbu ndị ọzọ n'oge ọgwụgwọ gị, gụnyere:

• Inwe ọgwụ na ụlọ ọgwụ
• Ijikwa anu ụlọ gị
• Nsogbu ọbara ọgbụgba
• Akọrọ ọnụ
• Iri calorie zuru oke
• Nchekwa nri n'oge ọgwụgwọ ọrịa kansa

Nwere ike belata nchekasị nke ọrịa site na isonyere ndị otu na-akwado ọrịa kansa. Kọrọ ndị ọzọ ihe ha na-eme na nsogbu niile nwere ike inyere gị aka ichewe naanị gị.

Outlook na-adabere na afọ mmadụ na ọkwa nke ọrịa. N'ọnọdụ ụfọdụ, ọrịa na-eto ngwa ngwa. N'ọnọdụ ndị ọzọ, ọ na-ewe ọtụtụ afọ tupu mgbaàmà apụta.

Ke ofụri ofụri, multiple myeloma bụ ọgwụgwọ, ma naanị na obere okwu nwere ike gwọrọ ya.

Akụrụ akụrụ bụ nsogbu ugboro ugboro. Ndị ọzọ nwere ike ịgụnye:

• Ọkpụkpụ fract
• Nnukwu calcium dị n'ọbara, nke nwere ike ịdị oke egwu
• Ohere ka mma maka ibute ọrịa, ọkachasị n’akpa ume
• Anaemia

Kpọọ onye na-eweta gị ma ọ bụrụ na ị nwere ọtụtụ myeloma na ị ga-ebute ọrịa, ma ọ bụ ụfụ, nhịahụ mmegharị, ma ọ bụ enweghị mmetụta.

Plasma cell dyscrasia; Plasma cell myeloma; Ọrịa plasmacytoma na-adịghị mma; Plasmacytoma nke ọkpụkpụ; Myeloma - otutu

• Ọkpụkpụ ụmị transplant - ihapu

• Cryoglobulinemia nke mkpịsị aka
• Usoro usoro ihe mgbochi
• Ihe mgbochi

Weebụsaịtị National Cancer Institute. PDQ cell neoplasms (tinyere otutu myeloma) ọgwụgwọ. www.cancer.gov/types/myeloma/hp/myeloma-treatment-pdq. Emelitere July 19, 2019. Nabata February 13, 2020.

National Comprehensive Cancer Network weebụsaịtị. NCCN usoro nlekọta ahụike na oncology: otutu myeloma. Dị 2.2020. www.nccn.org/professionals/physician_gls/pdf/myeloma.pdf. Emelitere October 9, 2019. Nabata February 13, 2020.

Rajkumar SV, Dispenzieri A. Otutu myeloma na nsogbu ndi ozo. Na: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff’s Clinical Oncology. Nke isii. Philadelphia, PA: Elsevier; 2020: isi nke 101.