Gout

Gout bụ ụdị ogbu na nkwonkwo. Ọ na - eme mgbe uric acid na - eto n’ime ọbara ma na - ebute mbufụt ke nkwonkwo.

Nnukwu gout bụ ọnọdụ na-egbu mgbu nke na-emetụtakarị naanị otu nkwonkwo. Gutọ ala ala bụ ugboro ugboro mgbu na mbufụt. Enwere ike imetụta ihe karịrị otu nkwonkwo.

Gout kpatara site n'inwe ogo uric acid dị elu karịa gị. Nke a nwere ike ime ma ọ bụrụ:

• Ahụ gị na-eme oke uric acid
• Ahụ gị nwere oge siri ike iwepu uric acid

Mgbe uric acid na-etolite na mmiri gburugburu nkwonkwo (mmiri synovial), kristal uric acid na-etolite. Kristal ndị a na-eme ka nkwonkwo ahụ ghara ịmị ọkụ, na-akpata ihe mgbu, ọzịza na ikpo ọkụ.

A maghị ezigbo ihe kpatara ya. Gout nwere ike ịgba ọsọ n'ezinụlọ. Nsogbu a na-adịkarị n’ebe ụmụ nwoke nọ, ụmụ nwaanyị na-emecha kwụsị ya, na-a peopleụkwa ndị na-a alcoholụ mmanya na-aba n’anya. Ka ndị mmadụ na-etolite, gout na-adịkarị ndị mmadụ.

Ọnọdụ ahụ nwekwara ike ịmalite na ndị nwere:

• Ọrịa shuga
• Ọrịa akụrụ
• Ibu
• Ọrịa Sickle cell anaemia na ọbara ọgbụgba ndị ọzọ
• Ọrịa kansa ọbara na ọrịa ọbara ndị ọzọ

Gout nwere ike ime mgbe ị nụsịrị ọgwụ ndị na-egbochi iwepụ uric acid na ahụ. Ndị mmadụ na-a certainụ ọgwụ ụfọdụ, dịka hydrochlorothiazide na ọgwụ ọgwụ ndị ọzọ, nwere ike nwee uric acid dị elu n'ọbara.

Mgbaàmà nke nnukwu gout:

• N'ọtụtụ ọnọdụ, ọ bụ naanị otu nkwonkwo ma ọ bụ ole na ole na-emetụta. Nnukwu mkpịsị ụkwụ, ikpere, ma ọ bụ nkwonkwo nkwonkwo ụkwụ na-emetụtakarị. Mgbe ụfọdụ, ọtụtụ nkwonkwo na-aza aza ma na-egbu mgbu.
• Mgbu ahụ na-amalite na mberede, oge mgbe n'abalị. Mgbu na-adịkarị njọ, nke akọwara dị ka ịkụ ọkpọ, ndakpọ, ma ọ bụ oke iwe.
• Nkwonkwo ahụ na-egosi ọkụ na uhie. Ọ na-adịkarị nro ma na-aza aza (ọ na-afụ ụfụ itinye mpempe akwụkwọ ma ọ bụ blanket na ya).
• Enwere ike ịnwe ahụ ọkụ.
• Mwakpo ahụ nwere ike ịla n'iyi na ụbọchị ole na ole, mana ọ nwere ike ịlaghachi site n'oge ruo n'oge. Mwakpo ndị ọzọ na-adịte aka.

Mgbu na ọzịza na-apụkarị mgbe mbuso agha mbụ gasịrị. Ọtụtụ mmadụ ga-enwe ọgụ ọzọ na ọnwa isii na-esote ọnwa iri na abụọ.

Fọdụ ndị nwere ike ibute gout adịghị ala ala. Nke a na-akpọ gouty ogbu na nkwonkwo. Ọnọdụ a nwere ike ibute mmebi njikọ na mwepu ngagharị na nkwonkwo. Ndị mmadụ na-adịghị ala ala gout ga-nkwonkwo mgbu na mgbaàmà ndị ọzọ ọtụtụ mgbe.

Nkwụnye ego nke uric acid nwere ike na-etolite akpụ n'okpuru anụ ahụ gburugburu nkwonkwo ma ọ bụ ebe ndị ọzọ dị ka ikiri ụkwụ, mkpịsị aka, na ntị. A na-akpọ akpụ ahụ tophus, nke sitere na Latin, nke pụtara ụdị okwute. Tophi (otutu akpụ) nwere ike ịmalite mgbe mmadụ nwesịrị gout ọtụtụ afọ. Ngwurugwu a nwere ike igbapu ihe nzu.

Ule nke enwere ike ime gunyere:

• Nyocha nke mmiri synovial (na-egosi kristal acid uric)
• Uric acid - ọbara
• -Zarị ọkụ (nwere ike ịbụ nkịtị)
• Sịva biopsy
• Uric acid - mmamịrị

Arịrị uric acid dị n'ọbara karịrị 7 mg / dL (milligram kwa deciliter) dị elu. Mana, obughi onye obula nwere nnukwu uric acid nwere gout.

Were ọgwụ maka gout ozugbo i nwere ike ma ọ bụrụ na ị nwere ọgụ ọhụrụ.

Were ọgwụ ndị na-adịghị egbochi ọgwụ ọjọọ (NSAIDs) dị ka ibuprofen ma ọ bụ indomethacin mgbe mgbaàmà malitere. Gwa onye na ahu maka ahuike gi banyere onodu kwesiri ekwesi. Ga-achọ ọgwụ siri ike karịa ụbọchị ole na ole.

• Ogwu ogwu ana akpo colchicine na enyere aka belata ihe mgbu, ọzịza, na mbufụt.
• Corticosteroids (dị ka prednisone) nwekwara ike ịdị oke irè. Onye na-enye gị nwere ike ịgbanye nkwonkwo ahụ ọkụ na steroid iji belata ihe mgbu.
• Site na mwakpo nke gout na nkwonkwo ọtụtụ enwere ike iji ọgwụ injecting a na-akpọ anakinra (Kineret).
• Mgbu ahụ na-agakarị n'ime awa iri na abụọ nke ịmalite ọgwụgwọ. Ọtụtụ oge, ihe mgbu niile agabigala n'ime awa 48.

Nwere ike ị medicinesụ ọgwụ kwa ụbọchị dịka allopurinol (Zyloprim), febuxostat (Uloric) ma ọ bụ probenecid (Benemid) iji belata ogo uric acid n'ọbara gị. Ingwedata uric acid na ihe na-erughị 6 mg / dL dị mkpa iji gbochie nkwụnye nke uric acid. Ọ bụrụ na ị nwere tophi a na-ahụ anya, uric acid kwesịrị ịdị obere karịa 5 mg / dL.

Nwere ike ịchọ ọgwụ ndị a ma ọ bụrụ:

• Have nwere ọtụtụ ọgụ n'otu afọ ahụ ma ọ bụ ọgụ gị dị oke njọ.
• I nwere mmebi nkwonkwo.
• Have nwere tophi.
• Have nwere ọrịa akụrụ ma ọ bụ okwute akụrụ.

Nri na mgbanwe ndụ nwere ike inyere aka gbochie ọgụ ọgụ:

• Belata mmanya na-aba n'anya, ọkachasị biya (mmanya ụfọdụ nwere ike inye aka).
• Kwụsị ibu ibu.
• Na-emega ahụ kwa ụbọchị.
• Belata oke oriri ị na-acha ọbara ọbara na ihe ọ sugụ sugụ na-atọ ụtọ.
• Họrọ nri di nma, dika nkpuru mmiri ara ehi, akwukwo nri, nkpuru osisi, nkpuru osisi, nkpuru osisi (nke na adighi ahihia nke oma) na nkpuru ahihia niile.
• Kọfị na vitamin C na-agbakwunye (nwere ike inyere ụfọdụ ndị aka).

Ngwọta kwesịrị ekwesị nke oke ọgụ na iwetu uric acid na ọkwa na-erughị 6 mg / dL na-enye ndị mmadụ ohere ibi ndụ dị mma. Otú ọ dị, ụdị ọrịa ahụ nwere ike ịga n'ihu na gout na-adịghị ala ala ma ọ bụrụ na anaghị agwọ nnukwu uric acid nke ọma.

Nsogbu nwere ike ịgụnye:

• Ọrịa ogbu na nkwonkwo na-adịghị ala ala.
• Nkume akụrụ.
• Nkwụnye ego na akụrụ, na-eduga n'ịda akụrụ na-adịghị ala ala.

A na - ejikọ nnukwu ọnụọgụ uric acid n’ime ọbara na ọrịa akụrụ na - arịwanye elu. A na-eme nnyocha iji chọpụta ma belata uric acid na-ebelata ihe ize ndụ maka ọrịa akụrụ.

Kpọọ onye na-eweta gị ma ọ bụrụ na ị nwere mgbaàmà nke oke ọrụ ogbu na nkwonkwo ma ọ bụ ọ bụrụ na ị mepee elu ugwu.

May gaghị enwe ike igbochi gout, mana ị nwere ike izere ihe ndị na-ebute mgbaàmà. Medicinesụ ọgwụ iji belata uric acid nwere ike igbochi ọganihu nke gout. N'ime oge, ego gị uric acid ga-apụ n'anya.

Ogbu na nkwonkwo - nnukwu; Gout - nnukwu; Hyperuricemia; Gophaceous gout; Tophi; Podagra; Gout - ala ala; Gut gout oge; Nnukwu gout; Ọrịa ogbu na nkwonkwo siri ike

• Nkume akụrụ na lithotripsy - nhapu
• Nkume akụrụ - nlekọta onwe gị
• Nkume akụrụ - ihe ị ga-ajụ dọkịta gị
• Usoro urinary percutaneous - ihapu

• Kristal Uric acid
• Tophi gout n'aka

Ọkụ CM, Wortmann RL. Clinical atụmatụ na ọgwụgwọ nke gout. Na: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Akwụkwọ Kelley na Firestein nke Rheumatology. Nke iri. Philadelphia, PA: Elsevier; 2017: isi 95.

Edwards NL. Ọrịa Crystal deposition. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke iri abụọ na ise. Philadelphia, PA: Elsevier Saunders; 2016: isi 273.

FitzGerald JD, Neogi T, Choi HK. Isi ederede: ekwela ka ndị gout enweghị mmasị na-eduga na ọrụ arthropathy. Ogbu na nkwonkwo Rheumatol. Ọrịa. 2017; 69 (3): 479-482. PMID: 28002890 www.ncbi.nlm.nih.gov/pubmed/28002890.

Khanna D, Fitzgerald JD, Khanna PP, et al. Mgbakwunye 2012 American College of Rheumatology መመሪያዎች maka njikwa gout. Nkebi nke 1: usoro ọgwụgwọ na-agwọ ọrịa na-eru nso na hyperuricemia. Ogbu na nkwonkwo na-elekọta Res (Hoboken). 2012; 64 (10): 1431-1446. PMID: 23024028 www.ncbi.nlm.nih.gov/pubmed/23024028.

Khanna D, Khanna PP, Fitzgerald JD, et al. Mgbakwunye Nchịkọta 2012 American College of Rheumatology maka njikwa gout. Nkebi nke 2: ọgwụgwọ na proinlalamic prophylaxis nke nnukwu ọrụ ogbu na nkwonkwo. Ogbu na nkwonkwo na-elekọta Res (Hoboken). 2012; 64 (10): 1447-1461. PMID: 23024029 www.ncbi.nlm.nih.gov/pubmed/23024029.

Gha JW, Gardner GC. Ojiji nke anakinra na ndị ọrịa nwere ọrịa ogbu na nkwonkwo metụtara kristal. J Rheumatol. 2019 pii: jrheum.181018. [Epub n'ihu mbipụta]. PMID: 30647192 www.ncbi.nlm.nih.gov/m/pubmed/30647192.