Ọrịa ọgbụgba

Cholestasis bụ ọnọdụ ọ bụla nke ọnya bile si na imeju na-akwụsịlata ma ọ bụ gbochie ya.

E nwere ọtụtụ ihe na-akpata cholestasis.

Extrahepatic cholestasis na-apụta n'èzí imeju. Enwere ike kpatara ya:

• Bile duct etuto ahụ
• Akpa
• Nkọwa nke eriri bile (nlezianya)
• Nkume dị na mmiri bile du
• Pancreatitis
• Pancreatic akpụ ma ọ bụ pseudocyst
• Nrụgide dị na nsị bile n'ihi oke ma ọ bụ akpụ dị nso
• Isi sclerosing cholangitis

Intrahepatic cholestasis na-eme n'ime imeju. Enwere ike kpatara ya:

• Ọrịa imeju na-egbu egbu
• Amyloidosis
• Ọrịa nje na imeju
• Inye nri naanị site na akwara (IV)
• Lymphoma
• Ime afọ ime
• Isi nke biliary cirrhosis
• Isi cancer ma ọ bụ metastatic cancer
• Isi sclerosing cholangitis
• Sarcoidosis
• Ọrịa ndị siri ike gbasaa site n'ọbara (sepsis)
• Ụkwara nta
• Malitere ịrịa ịba ọcha n'anya

Medicinesfọdụ ọgwụ nwekwara ike ịkpata cholestasis, gụnyere:

• Ọgwụ nje, dịka ampicillin na penicillins ndị ọzọ
• Anabolic steroid
• Mgbochi ọgwụ ịmụ nwa
• Chlorpromazine
• Cimetidine
• Nkume
• Imipramine
• Prochlorperazine
• Terbinafine
• Tolbutamide

Mgbaàmà nwere ike ịgụnye:

• Akwa ma ọ bụ oche ọcha
• Miri mamiri
• Enweghi ike iri nri ụfọdụ
• Itching
• Nausea ma ọ bụ vomiting
• Mgbu dị n'akụkụ aka nri nke elu afọ
• Agba odo ma ọ bụ anya

Nnwale ọbara nwere ike igosi na ị buliri bilirubin na alkaline phosphatase elu.

A na-eji nyocha eserese achọpụta ọnọdụ a. Ule gụnyere:

• Nyocha CT nke afọ
• MRI nke afọ
• Endoscopic retrograde cholangiopancreatography (ERCP), nwekwara ike ikpebi ihe kpatara ya
• Ultrasound nke afọ

A ghaghị ịgwọ ihe kpatara kpatara cholestasis.

Otú mmadụ si eme nke ọma dabere n’ọrịa na-akpata ọnọdụ ahụ. Nkume dị na mmiri bile nkịtị nwere ike iwepụ mgbe mgbe. Nke a nwere ike ịgwọ cholestasis.

Enwere ike itinye stent iji mepee mpaghara nke mmiri bile nkịtị na-adị warara ma ọ bụ na-egbochi ya site na ọrịa kansa.

Ọ bụrụ na ọ bụ iji ọgwụ ụfọdụ eme ihe na-akpata ọnọdụ ahụ, ọ ga-apụkarị mgbe ị kwụsịrị ị thatụ ọgwụ ahụ.

Nsogbu nwere ike ịgụnye:

• Afọ ọsịsa
• Organis ọdịda nwere ike ime ma ọ bụrụ na sepsis amalite
• Enweghị ike ịmịkọrọ abụba na abụba na-edozi mmiri
• Ọkụ siri ike
• Ọkpụkpụ na-esighị ike (osteomalacia) n'ihi na ọ nwere cholestasis ruo ogologo oge

Kpọọ onye nlekọta ahụike gị ma ọ bụrụ na ịnwee:

• Itching na-anaghị apụ apụ
• Agba odo ma ọ bụ anya
• Ihe mgbaàmà ndị ọzọ nke cholestasis

Bido ịgba ọgwụ mgbochi ọrịa maka ịba ọcha n'anya A na B ọ bụrụ na ị nọ n’ihe ize ndụ. Ejila ọgwụ igba ogwu ma kesaa ogwu.

Intrahepatic cholestasis; Ihe omuma cholesterol

• Nkume okwute
• Gallbladder
• Gallbladder

Eaton JE, Lindor KD. Primary biliary cholangitis. Na: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger na Ọrịa Gastrointestinal and Livertran. Nke 11. Philadelphia, PA: Elsevier; 2021: Isi nke 91.

Fogel EL, Sherman S. Ọrịa nke gallbladder na bile ducts. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke 26th. Philadelphia, PA: Elsevier; 2020: isi 146.

Lidofsky SD. Jaundice. Na: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger na Ọrịa afọ na ọrịa Fordtran. Nke 11. Philadelphia, PA: Elsevier; 2021: Isi 21.