Ọgwụ Coronavirus (COVID-19): akwadoro ma na-amụ ihe

Ndinaya

• Ekwadoro ọgwụgwọ maka coronavirus
• Ngwọta a na-amụ
• 1. Ivermectin
• 2. Plitidepsin
• 3. Ntughari
• 4. Dexamethasone
• 5. Hydroxychloroquine na chloroquine
• 6. Colchicine
• 7. Mefloquine
• 8. Tocilizumab
• 9. Plasma na-emetụ ihe n’ahụ
• 10. Avifavir
• 11. Baricitinib
• 12. Ọpụpụ-CD24
• Ngwọta ọgwụgwọ maka ọgwụgwọ coronavirus

Ka ọ dị ugbu a, enweghị ọgwụ ndị a ma ama nwere ike iwepu coronavirus ọhụrụ ahụ na, n'ihi nke a, n'ọtụtụ ọnọdụ, a na-eme ọgwụgwọ site na naanị usoro ole na ole na ọgwụ nwere ike ịkwụsị mgbaàmà nke COVID-19.

Enwere ike ịgwọ okwu ndị dị ntakịrị, yana mgbaàmà ndị yiri flu, na-ezu ike n'ụlọ, izu ike, yana ọgwụ ọgwụ ọkụ na ihe mgbu. Okwu ikpe kachasị njọ, bụ nke ihe mgbaàmà na nsogbu ndị ọzọ dị ka oyi baa na-egosi, ọ dị mkpa ka a gwọọ ha mgbe ha batara n'ụlọ ọgwụ, mgbe mgbe na Ngalaba Nlekọta Nlekọta (ICU), iji hụ, ọkachasị, nchịkwa zuru oke nke ikuku oxygen na nlekota nke ihe ịrịba ama dị mkpa.

Hụ nkọwa ndị ọzọ gbasara ọgwụgwọ maka COVID-19.

Na mgbakwunye na ọgwụ, ụfọdụ ọgwụ mgbochi megide COVID-19 ka a na-amụ, mepụta ma kesaa. Mkpụrụ ọgwụ ndị a na-ekwe nkwa igbochi ọrịa COVID-19, mana ha yikwara ka ọ na-ebelata ike mgbaàmà mgbe ọrịa ahụ mere. Nghọta nke ọma nke ọgwụ mgbochi megide COVID-19 dị, otu ha si arụ ọrụ na mmetụta ndị nwere ike.

Ekwadoro ọgwụgwọ maka coronavirus

Ọgwụ ndị anabatara maka ọgwụgwọ coronavirus, nke Anvisa na Ngalaba Ahụike, bụ ndị nwere ike ịkwụsị mgbaàmà nke ọrịa ahụ, dị ka:

• Ọgwụ Ọgwụ: wedata okpomọkụ ma lụsoo ọgụ ọkụ;
• Mgbu na-egbu mgbu: iji belata ahụ mgbu mgbu na ahụ dum;
• Ọgwụ nje: iji gwọọ nje nwere ike ibute COVID-19.

Ekwesịrị iji ọgwụ ndị a mee ihe naanị n'okpuru nduzi nke dọkịta ma, ọ bụ ezie na a kwadoro ha maka ọgwụgwọ nke coronavirus ọhụrụ ahụ, ha enweghị ike iwepu nje ahụ na ahụ, mana ejiri ya naanị iji belata mgbaàmà ma melite nkasi obi nke onye oria a.

Ngwọta a na-amụ

Na mgbakwunye ọgwụ ndị na-enyere aka ịkwụsị mgbaàmà, ọtụtụ mba na-emepe emepe ọmụmụ banyere anụmanụ ụlọ nyocha na ndị ọrịa nwere ọrịa iji gbalịa ịchọpụta ọgwụ nwere ike iwepu nje ahụ n'ahụ.

Ekwesighi iji ọgwụ eji amụ ihe na enweghị ntụzịaka nke onye dibia, maọbụ ụzọ iji gbochie ọrịa, n’ihi na ha nwere ike bute mmetuta dị iche iche ma bụrụ ihe iyi ndụ egwu.

Ihe ndị a bụ ndepụta nke ọgwụ ndị isi a na-amụ maka coronavirus ọhụrụ:

1. Ivermectin

Ivermectin bụ vermifuge gosipụtara maka ọgwụgwọ nke nje ndị ọzọ, nke na-akpata nsogbu ndị dị ka onchocerciasis, elephantiasis, pediculosis (lice), ascariasis (roundworms), scabies ma ọ bụ eriri afọ ikeyloidiasis na nke, na nso nso a, egosiputa ezigbo nsonaazụ na mkpochapu nke coronavirus ọhụrụ, in vitro.

Otu nnyocha e mere na Australia, nwalere ivermectin na laabu, na sel ọdịbendị in vitro, a chọpụtara na ihe a nwere ike iwepu nje SARS-CoV-2 n'ime elekere 48 ^[7]. Otú ọ dị, a na-achọ ịnwale ọnwụnwa ụmụ mmadụ iji chọpụta ịdị irè ya in vivo, yana ọgwụ ọgwụgwọ na nchekwa nke ọgwụ ahụ, nke a na-atụ anya na ọ ga-eme n'oge n'etiti ọnwa 6 ruo ọnwa 9.

Tụkwasị na nke ahụ, nchọpụta ọzọ gosiri na ojiji nke ivermectin site n'aka ndị ọrịa a chọpụtara na COVID-19 na-anọchite anya mbelata nke nsogbu na ọrịa na-aga n'ihu, na-egosi na ivermectin nwere ike imeziwanye amụma nke ọrịa ahụ ^[33]. N'otu oge ahụ, nnyocha e mere na Bangladesh gosiri na ojiji nke ivermectin (12 mg) maka ụbọchị 5 dị irè ma dịkwa mma na ọgwụgwọ nke COVID-19 ^[34].

Na Nọvemba 2020 ^[35] Nkwupụta nke ndị nchọpụta India na ivermectin ga-enwe ike igbochi mbugharị nke nje ahụ na mkpụrụ ndụ nke mkpụrụ ndụ, igbochi mmepe nke ọrịa ahụ, ka e bipụtara na akwụkwọ akụkọ sayensị, agbanyeghị mmetụta a ga-ekwe omume naanị site na nnukwu doses nke ivermectin, nke ọ nwere ike ịbụ nsi na ahu mmadu.

Ọmụmụ ọzọ wepụtara na Disemba 2020 ^[36] o gosikwara na ojiji nke nanoparticles nwere ivermectin nwere ike ibelata nkwupụta nke mkpụrụ ndụ 'ACE2 receptors, na-ebelata ihe gbasara nke puru omume nke nje ahụ iji jikọta ndị a na-ebute ma bute ọrịa. Otú ọ dị, a na-eme nchọpụta a naanị na vitro, ọ gaghị ekwe omume ịsị na nsonaazụ ya ga-abụ otu na vivo. Na mgbakwunye, dịka nke a bụ usoro ọgwụgwọ ọhụrụ, ọmụmụ nsị dị mkpa.

N'agbanyeghị nsonaazụ ndị a, a chọkwuru ọmụmụ ihe iji gosipụta arụmọrụ nke ivermectin na ọgwụgwọ nke COVID-19, yana mmetụta ya na igbochi ọrịa. Hụ ihe banyere ojiji nke ivermectin megide COVID-19.

July 2, 2020 Mmelite:

São Paulo Regional Pharmacy Council (CRF-SP) wepụtara akwụkwọ nyocha ^[20] n'ime ya ọ na-ekwu na ọgwụ ivermectin na-egosi ihe mgbochi nje na ụfọdụ ọmụmụ in-vitro, mana na ọ dị mkpa nyocha ọzọ iji tụlee na enwere ike iji ivermectin mee ihe n'enweghị nsogbu n'ime ụmụ mmadụ megide COVID-19.

N'ihi ya, ọ na-adụ ọdụ na ire ivermectin kwesịrị ka eme ya naanị site na ngosipụta nke ọgwụ ọgwụ yana n'ime oge na oge dọkịta gwara ya.

July 10, 2020 Mmelite:

Dika nkowa doro anya nke ANVISA weputara ^[22], enweghi omumu ihe omumu nke gosiputara ojiji nke ivermectin maka ọgwụgwọ nke COVID-19, na iji ogwu ogwu oria oria ohuru ohuru kwesiri ibu oru nke ndi dibia nke na-eduzi ogwu.

Na mgbakwunye, nsonaazụ mbụ wepụtara site na nyocha nke USP's Institute of Biomedical Sciences (ICB) ^[23], na-egosi na ivermectin, ọ bụ ezie na ọ nwere ike iwepụ nje ahụ na mkpụrụ ndụ ndị na-arịa ọrịa na ụlọ nyocha, na-emekwa ka ọnwụ nke mkpụrụ ndụ ndị a, nke nwere ike igosi na ọgwụ a nwere ike ọ gaghị abụ ọgwụgwọ kacha mma.

Melite Disemba 9, 2020:

N'ime akwụkwọ wepụtara site n'aka ndị German Society of Disease Infective (SBI) ^[37] egosiri na enweghi nkwanye maka ogwu ogwu na / ma obu prophylactic maka COVID-19 na ogwu obula, tinyere ivermectin, ebe obu na ihe omumu omumu omumu emere na egosiputa uru na, dabere na onodu ogwu, ejiri, nwere ike jikọta na mmetụta ndị nwere ike ịpụta nsonaazụ ahụ ike mmadụ n'ozuzu ya.

Melite February 4, 2021:

Merck, nke bụ ụlọ ọrụ ọgwụ na-ahụ maka mmepụta ọgwụ ọgwụ Ivermectin, gosipụtara na n'ọmụmụ ihe ndị ahụ emeghị ka ọ mata ihe ọ bụla sayensị na-egosi na usoro ọgwụgwọ nke ọgwụ a megide COVID-19, ma ọ bụ na ọ chọpụtaghị mmetụta na ndị ọrịa. achọpụtagoro na ọ bụ ọrịa ahụ.

2. Plitidepsin

Plitidepsin bụ ọgwụ mgbochi akpụ nke emepụtara site na ụlọ nyocha Spanish nke egosiri maka ọgwụgwọ ụfọdụ ikpe nke ọtụtụ myeloma, mana nke nwekwara mmetụta mgbochi nje siri ike megide coronavirus ọhụrụ.

Dị ka otu nnyocha e mere na United States si dị ^[39], plitidepsin nwere ike belata ibu nje nke coronavirus ruo ihe ruru 99% n'ime akpa ume nke oke nyocha ụlọ nyocha nwere ọrịa COVID-19. Ndị nyocha gosipụtara na ihe ịga nke ọma ọgwụ ahụ nwere na ike igbochi protein dị na sel nke dị mkpa maka nje ahụ ịba ụba ma gbasaa n'ime ahụ niile.

Nsonaazụ ndị a, yana eziokwu ahụ bụ na a na-eji ọgwụ a eme ihe n'ime ụmụ mmadụ maka ọgwụgwọ nke ọtụtụ myeloma, na-egosi na ọgwụ ahụ nwere ike ịdị mma ịnwale ndị ọrịa mmadụ nwere ọrịa COVID-19. Ya mere, ọ dị mkpa ichere maka nsonaazụ ule ndị a iji ghọta usoro ọgwụgwọ na ọgwụ nwere ike ịgwụ.

3. Ntughari

Nke a bụ ọgwụ na-ebuso nje virus zuru oke nke mepụtara iji na-agwọ ọrịa oria Ebola, mana egosighi nsonaazụ ọma dịka ihe ndị ọzọ. Agbanyeghị, n'ihi oke ọrụ ya megide nje, a na-amụ ya iji ghọta ma ọ nwere ike ị nweta nsonaazụ kacha mma na mkpochapụ nke coronavirus ọhụrụ.

Ihe omumu mbu emere na ulo ogwu na ogwu a, ma na United States ^{[1] [2]}, dị ka ọ dị na China ^[3], gosipụtara mmetụta dị mma, ebe ihe ahụ nwere ike igbochi mmegharị na ịba ụba nke coronavirus ọhụrụ ahụ, yana nje ndị ọzọ nke ezinụlọ coronavirus.

Otú ọ dị, tupu a gwa ya dị ka ụdị ọgwụgwọ, ọgwụ a kwesịrị ịga ọtụtụ ọmụmụ mmadụ, iji ghọta ezi nrụpụta ọrụ ya na nchekwa ya. Ya mere, enwere, n'oge a, ihe gbasara ọmụmụ 6 a na-arụ na ọnụ ọgụgụ dị elu nke ndị ọrịa bu ọrịa COVID-19, ma na United States, na Europe na Japan, mana nsonaazụ ya kwesịrị ịhapụ na Eprel , maka oge a, enweghị ihe akaebe na Remdesivir nwere ike, n'eziokwu, jiri ya mee ihe iji kpochapụ coronavirus ọhụrụ n'ime ụmụ mmadụ.

Eprel 29, 2020 Mmelite:

Dika nyocha nke Science Sciences ^[8], na United States, ojiji nke Remdesivir na ndị ọrịa nwere COVID-19 yiri ka ọ na-eweta otu nsonaazụ ahụ na oge ọgwụgwọ nke 5 ma ọ bụ 10 ụbọchị, na n'ọnọdụ abụọ ndị ọrịa na-ahapụ ụlọ ọgwụ n'ihe dịka ụbọchị 14 na akụkụ ahụ. mmetụta dịkwa ala. Ihe omumu a egosighi ogo ogwu ogwu iji kpochapu coronavirus ohuru na, ya mere, ihe omumu ndi ozo ka na eme.

Nwere ike 16, 2020 Mmelite:

Otu nnyocha na China na ndị ọrịa 237 nwere oke mmetụta nke ọrịa COVID-19 ^[15] kọrọ na ndị ọrịa ejiri ọgwụ a gwọọ gosipụtara mgbatị dịtụ ngwa ma e jiri ya tụnyere ndị ọrịa na-achịkwa, yana nkezi nke ụbọchị 10 ma e jiri ya tụnyere ụbọchị 14 nke ndị otu ahụ gosipụtara na placebo.

Melite Mee 22, 2020:

Nkwupụta mbido nke nyocha ọzọ emere na United States na Remdesivir ^[16] gosikwara na ojiji nke ọgwụ a yiri ka ọ ga-ebelata oge mgbake na ndị toro eto nọ n'ụlọ ọgwụ, yana iji belata ihe ize ndụ nke ibute ọrịa ngwangwa dị ala.

Melite July 26, 2020:

Dị ka ọmụmụ nke Bostonlọ Akwụkwọ Mahadum Boston nke Ahụ Ike Ọha ^[26], remdesivir na-ebelata oge ọgwụgwọ na ndị ọrịa kwetara na ICU.

November 5, 2020 Mmelite:

Akụkọ ikpeazụ nke ọmụmụ a na-eme na United States na Remdesivir na-egosi na ojiji nke ọgwụ a, n'eziokwu, belata oge mgbake na ndị okenye nọ n'ụlọ ọgwụ, site na 15 ruo 10 ụbọchị. ^[31].

November 19, 2020 Mmelite:

FDA na United States enyela ikike mberede ^[32] nke na-enye ohere ijikọ Remdesivir yana ọgwụ Baricitinib, n'ịgwọ ndị ọrịa nwere ọrịa coronavirus siri ike ma chọọ oxygenation ma ọ bụ ikuku.

November 20, 2020 Mmelite:

Onye WHO nyere ndụmọdụ ka eji Remdesivir na ọgwụgwọ ndị ọrịa na COVID-19 n'ihi enweghị data zuru oke na-egosi na Remdesivir na-ebelata ọnụọgụ ọnwụ.

4. Dexamethasone

Dexamethasone bụ ụdị corticosteroid a na-ejikarị eme ihe maka ndị ọrịa nwere nsogbu iku ume na-adịghị ala ala, dị ka ụkwara ume ọkụ, mana enwere ike iji ya na nsogbu ndị ọzọ na-adịghị mma, dị ka ọrịa ogbu na nkwonkwo ma ọ bụ mbufụt anụ. Anwalewo ọgwụ a dị ka ụzọ iji belata mgbaàmà nke COVID-19, n'ihi na ọ nwere ike inye aka belata nsị na ahụ.

Dabere na nyocha a na-eme na UK ^[18], dexamethasone yiri ka ọ bụ ọgwụ mbụ anwale iji belata oke ọnụọgụ ọnụọgụ nke ndị ọrịa na-arịa ọrịa siri ike na COVID-19. Site na nsonaazụ nke ọmụmụ ahụ, dexamethasone jisiri ike belata ọnụ ọgụgụ ọnwụ site na ruo ụbọchị iri abụọ na asatọ mgbe ọrịa na coronavirus ọhụrụ, ọkachasị ndị mmadụ chọrọ ka enyere ha aka na ventilator ma ọ bụ nye ikuku oxygen.

Ọ dị mkpa icheta na dexamethasone anaghị ekpochapụ coronavirus na ahụ, naanị na-enyere aka ịkwụsị mgbaàmà ma zere nsogbu ndị ka njọ.

June 19, 2020 Mmelite:

Braziliantù Na-ahụ Maka Ọrịa Na-ahụ Maka Ọrịa na Brazil kwadoro ka eji dexamethasone maka ụbọchị 10 maka ọgwụgwọ nke ndị ọrịa niile nwere COVID-19 kwetara na ICU site na ikuku ventilashị ma ọ bụ ndị chọrọ ịnweta oxygen. Agbanyeghị, ekwesighi iji corticosteroids n'ọnọdụ ndị dị nwayọ ma ọ bụ dịka ụzọ isi egbochi ọrịa ^[19].

Melite July 17, 2020:

Dika nyocha sayensi emere na United Kingdom ^[24], ọgwụgwọ dexamethasone maka ụbọchị 10 n'usoro yiri ka ọ na-ebelata ọnụ ọgụgụ ndị nwụrụ anwụ na ndị ọrịa nwere ọrịa siri ike site na coronavirus ọhụrụ ahụ, bụ ndị chọrọ ventilator. N'okwu ndị a, ọnụọgụ ọnwụ na-egosi ibelata site na 41.4% rue 29.3%. Na ndị ọrịa ndị ọzọ, mmetụta nke ọgwụgwọ na dexamethasone egosighi nsonaazụ ndị a akara.

Melite Septemba 2, 2020:

Ihe nyocha nke dabere na ule nyocha 7 ^[29] kwubiri na iji dexamethasone na corticosteroid ndị ọzọ nwere ike, n’ezie, belata ọnwụ na ndị ọrịa siri ike bu ọrịa COVID-19.

Melite Septemba 18, 2020:

Agencylọ Ọrụ Ọgwụ Europe (EMA) ^[30] kwadoro iji dexamethasone na ọgwụgwọ nke ndị nọ n'afọ iri na ụma na ndị toro eto na-ebute ọrịa coronavirus ọhụrụ ahụ, bụ ndị chọrọ nkwado oxygen ma ọ bụ ikuku ventilashị.

5. Hydroxychloroquine na chloroquine

Hydroxychloroquine, yana chloroquine, bụ ihe abụọ a na-eji agwọ ndị ọrịa ịba, lupus na ụfọdụ nsogbu ahụ ike ndị ọzọ, mana nke a ka anaghị eche na ọ dị mma n'ihe niile nke COVID-19.

Ọmụmụ ihe emere na France ^[4] na China ^[5], gosipụtara mmetụta dị mma nke chloroquine na hydroxychloroquine na mbenata nje virus na ibelata mbugharị nke nje ahụ n'ime sel, na-ebelata ikike nke nje ịba ụba, na-enye, ya mere, mgbake ngwa ngwa. Otú ọ dị, a na-eme nnyocha ndị a na obere ihe nlele ma ọ bụghị ule niile dị mma.

Maka ugbu a, dị ka Ministry of Health nke Brazil si kwuo, enwere ike iji chloroquine mee ihe na ndị mmadụ nabatara n'ụlọ ọgwụ, maka ụbọchị 5, n'okpuru nyocha na-adịgide adịgide, iji nyochaa ọdịdị nke mmetụta dị egwu dị egwu, dị ka nsogbu obi ma ọ bụ mgbanwe ọhụụ .

Eprel 4, 2020 Mmelite:

Otu n'ime ọmụmụ ihe na-aga n'ihu, yana ijikọ hydroxychloroquine na ọgwụ nje azithromycin ^[9], na France, gosipụtara nsonaazụ na-ekwe nkwa na otu ìgwè nke ndị ọrịa 80 nwere akara ngosi dị ala nke COVID-19. N'ime otu a, amatapụtara mbelata nke nje virus nke coronavirus ọhụrụ n'ime ahụ, mgbe ihe dị ka ụbọchị 8 nke ọgwụgwọ, nke bụ ihe na-erughị nkezi nke izu 3 nke ndị mmadụ na-enwetaghị ọgwụgwọ ọ bụla.

N'ime nchọpụta a, n'ime ndị ọrịa 80 mụtara, naanị mmadụ 1 nwụrụ, n'ihi na a gaara anabata ya n'ụlọ ọgwụ na ọkwa dị oke oke nke ọrịa ahụ, nke nwere ike igbochi ọgwụgwọ.

Nsonaazụ ndị a na-aga n'ihu na-akwado nkwupụta na iji hydroxychloroquine nwere ike ịbụ ụzọ dị mma iji gwọọ ọrịa COVID-19, ọkachasị na ọnọdụ nke mgbaàmà dị nro ma na-adịchaghị mma, na mgbakwunye na ibelata ihe ize ndụ nke mbufe ọrịa. N'agbanyeghị nke ahụ, ọ dị mkpa ichere maka nsonaazụ nke ọmụmụ ndị ọzọ a na-eme na ọgwụ ahụ, iji nweta nsonaazụ na ọnụ ọgụgụ ndị ka ukwuu.

Eprel 23, 2020 Mmelite:

Ndị Federal Council of Medicine nke Brazil kwadoro iji Hydroxychloroquine yana Azithromycin na nghọta nke dọkịta, na ndị ọrịa nwere mgbaàmà dị nro ma ọ bụ nke na-adịghị agafe agafe, mana ndị na-achọghị nnabata ICU, bụ nke ọrịa nje ndị ọzọ, dị ka Influenza ma ọ bụ H1N1 , na nyocha nke COVID-19 kwadoro ^[12].

Ya mere, n'ihi enweghị ezigbo nsonaazụ sayensị, a ga-eji ngwakọta ọgwụ a mee ihe site na nkwenye onye ọrịa na nkwanye dọkịta, mgbe ị nyochachara ihe egwu dị na ya.

Nwere ike 22, 2020 Mmelite:

Dị ka otu nnyocha e mere na United States na 811 ọrịa ^[13], ojiji nke Chloroquine na Hydroxychloroquine, nke jikọtara ma ọ bụ na azithromycin, adịghị ka ọ nwere mmetụta bara uru na ọgwụgwọ nke COVID-19, ọbụnadị yiri ka ọ na-egbu ọnụọgụ ọnụọgụ abụọ nke ndị ọrịa, ebe ọ bụ na ọgwụ ndị a na-eme ka ohere nke nsogbu obi nwee nsogbu, karịsịa arrhythmia na atr fibrillation.

Ka ọ dị ugbu a, nke a bụ ọmụmụ ihe kasịnụ ejiri hydroxychloroquine na chloroquine mee. Ebe ọ bụ na nsonaazụ ndị e gosipụtara na-emegide ihe ekwuru banyere ọgwụ ndị a, a ka chọkwuru ọmụmụ ihe.

Nwere ike 25, 2020 Mmelite:

Healthtù Ahụ Ike Worldwa (WHO) akwụsịtụla nyocha nwa oge na hydroxychloroquine nke ọ chịkọtara n'ọtụtụ mba. Ekwesịrị ịnọgide na nkwusioru ruo mgbe nyochachara ọgwụ ahụ.

Nwere ike 30, 2020 Mmelite:

Ọnọdụ nke Espírito Santo, na Brazil, wepụrụ ihe ngosi nke iji chloroquine na ndị ọrịa nwere COVID-19 nọ n'ọnọdụ dị njọ.

Na mgbakwunye, ndị ọka iwu sitere na Federal Public Ministry nke São Paulo, Rio de Janeiro, Sergipe na Pernambuco na-arịọ ka a kwụsịtụ ụkpụrụ na-egosi iji hydroxychloroquine na chloroquine na-agwọ ndị ọrịa nwere COVID-19.

June 4, 2020 Mmelite:

Magazin Lancet wepụrụ akwụkwọ nke ọmụmụ nke ndị ọrịa 811 nke gosipụtara na iji hydroxychloroquine na chloroquine enweghị uru bara uru maka ọgwụgwọ nke COVID-19, n'ihi ihe isi ike ịnweta data mbụ e gosipụtara na ọmụmụ ihe ahụ.

June 15, 2020 Mmelite:

FDA, nke bụ isi na-achịkwa ọgwụ na United States, ewepụla ikike mberede maka iji chloroquine na hydroxychloroquine na ọgwụgwọ nke COVID-19 ^[17], na-eme ka ọnụọgụ dị elu nke ọgwụ ahụ na-egosi na ikike dị ala maka ọgwụgwọ nke coronavirus ọhụrụ ahụ.

Melite July 17, 2020:

Braziliantù Na-ahụ Maka Ọrịa Na-ahụ Maka Ọrịa na Brazil ^[25] na-atụ aro ka a hapụ ojiji nke hydroxychloroquine na ọgwụgwọ nke COVID-19, n'oge ọ bụla nke ọrịa ahụ.

July 23, 2020 Mmelite:

Dị ka otu nnyocha e mere na Brazil ^[27], emekọtara ọnụ n'etiti Albert Einstein, HCor, Sírio-Libanês, Moinhos de Vento, Oswaldo Cruz na Beneficência Portuguesa Hospital, iji hydroxychloroquine, jikọtara ma ọ bụ na azithromycin ejikọtaghị, ọ dị ka ọ nweghị mmetụta ọ bụla na ọgwụgwọ nke ndị dị nwayọọ ruo obere ndị ọrịa nwere coronavirus ọhụrụ.

6. Colchicine

Dị ka otu nnyocha e mere na Canada ^[38], colchicine, ọgwụ a na-ejikarị agwọ ọrịa rheumatological, dị ka gout, nwere ike inye aka n'ịgwọ ndị ọrịa nwere COVID-19.

Dabere na ndị ọrụ nyocha ahụ, otu ndị ọrịa ejiri ọgwụ a gwọọ kemgbe nyochachara ọrịa ahụ, ma e jiri ya tụnyere otu jiri placebo, gosipụtara mbelata dị egwu nke ịmalite ụdị ọrịa ahụ siri ike. Tụkwasị na nke a, a na-ekwupụtakwa mbelata nke ụlọ ọgwụ na ọnụ ọgụgụ ọnwụ.

7. Mefloquine

Mefloquine bụ ọgwụ egosiri maka igbochi na ọgwụgwọ ọrịa ịba, na ndị mmadụ bu n'obi ịga ebe ndị ọrịa jupụtara. Dabere na ọmụmụ emere na China na Italytali^[6], usoro ọgwụgwọ nke mefloquine yana ọgwụ ndị ọzọ ka a na-amụ na Russia iji nyochaa ịdị irè ya na ịchịkwa ọrịa COVID-19, mana enweghi nsonaazụ doro anya.

N'ihi ya, a naghị atụ aro iji mefloquine na-emeso ọrịa na coronavirus ọhụrụ n'ihi na achọrọkwu ọmụmụ iji gosipụta nrụpụta ọrụ ya na nchekwa ya.

8. Tocilizumab

Tocilizumab bụ ọgwụ na-ebelata ihe sistemụ ahụ ji arụ ọrụ, ya mere, a na-ejikarị ya agwọ ndị ọrịa nwere ọrịa ogbu na nkwonkwo, iji belata mmeghachi ahụ na-adịghị mma, na-ebelata mbufụt ma na-ebelata mgbaàmà.

A na-amụ ọgwụ a iji nyere aka na ọgwụgwọ nke COVID-19, ọkachasị na ọkwa dị elu nke ọrịa, mgbe enwere ọnụọgụ nke ihe na-adịghị mma nke usoro ahụ ji alụso ọrịa ọgụ na-emepụta, nke nwere ike ịka njọ ọnọdụ ahụike.

Dị ka otu nnyocha na China ^[10] n'ime ndị ọrịa 15 bu nje COVID-19, ojiji nke tocilizumab gosipụtara na ọ dị irè karị ma na-akpata mmetụta dị ole na ole, ma e jiri ya tụnyere corticosteroids, nke bụ ọgwụ ndị a na-ejikarị ejikwa mbufụt eme site na nzaghachi mgbochi.

N'agbanyeghị nke ahụ, ọ dị mkpa ka e mekwuo ọmụmụ ihe, iji ghọta ihe kachasị mma, chọpụta usoro ọgwụgwọ ma chọpụta ihe mmetụta ndị nwere ike.

Eprel 29, 2020 Mmelite:

Dika nyocha ohuru emere na China na ndi oria 21 oria COVID-19^[14], ọgwụgwọ na tocilizumab yiri ka ọ nwere ike belata mgbaàmà nke ọrịa ahụ n'oge na-adịghị anya mgbe ọgwụchara ọgwụ ahụ gasịrị, belata ahụ ọkụ, na-ebelata mmetụta nke ịmachi aka n'ime obi ma melite ogo oxygen.

Emere ihe ọmụmụ a na ndị ọrịa nwere nnukwu mgbaàmà nke ọrịa ahụ ma na-atụ aro na ọgwụgwọ na tocilizumab kwesịrị ịmalite ozugbo o kwere mee mgbe onye ọrịa si n'ọnọdụ na-adịghị agafe agafe gaa n'ọnọdụ dị njọ nke ibute ọrịa coronavirus ọhụrụ ahụ.

Melite July 11, 2020:

Nchoputa ohuru nke Mahadum Michigan di na United States ^[28], kwubiri na ojiji nke tocilizumab na ndị ọrịa nwere COVID-19 yiri ka ọ na-ebelata ọnụọgụ ọnwụ nke ndị ọrịa na-eme ka ikuku gbapụ, n'agbanyeghị na ọ mụbara ohere nke ọrịa ndị ọzọ.

9. Plasma na-emetụ ihe n’ahụ

Plasma convalescent bụ ụdị ọgwụgwọ na-agwọ ọrịa nke a na-ewe ọbara, site n'aka ndị mmadụ bu nje coronavirus na ndị a gbakeere, ndị na-emezi usoro ịmịnye ọgwụ iji kewaa plasma na mkpụrụ ndụ ọbara uhie. N'ikpeazụ, a na-etinye plasma a n'ime onye ọrịa iji nyere aka usoro ahụ ji alụso nje ọgụ ọgụ.

Ozizi a na-akọwa ụdị ọgwụgwọ a bụ na ihe nje ndị ahụ n'ahụ onye butere ọrịa ahụ, nke wee dịrị na plasma, nwere ike ibuga n'ọbara onye ọzọ ka na-arịa ya, na-enyere aka iwusi ike Ọrịa na ikwado iwepụ nje ahụ.

Dabere na Nka na ụzụ Nka nke 21 nke Anvisa wepụtara, na Brazil, enwere ike iji plasma convalescent dị ka nnwale nnwale nye ndị ọrịa bu nje coronavirus ọhụrụ ahụ, ọ bụrụhaala na agbasoro iwu Iwu Ahụike niile. Tụkwasị na nke ahụ, a ghaghị ịkọọrọ ikpe niile na-eji plasma convalescent maka ọgwụgwọ nke COVID-19 na General Coordination of Blood and Blood Products of the Ministry of Health.

10. Avifavir

Avifavir bụ ọgwụ mepụtara na Russia nke ihe ọrụ ya bụ ihe favipiravir, nke dị ka Russian Direct Investment Fund (RDIF) si kwuo ^[21] nwere ike ịgwọ ọrịa coronavirus, etinyegoro ya na usoro ọgwụgwọ na mgbochi nke COVID-19 na Russia.

Dị ka ọmụmụ a na-eme, n'ime ụbọchị 10, Avifavir enweghị mmetụta ọhụụ ọ bụla na, n'ime ụbọchị 4, 65% nke ndị ọrịa a gwọrọ nwere ule na-adịghị mma maka COVID-19.

11. Baricitinib

FDA nyere ikike iji ọgwụ ọjọọ Baricitinib eme ihe n'ịgwọ nnukwu ọrịa COVID-19 ^[32]na mkpokọta na Remdesivir. Baricitinib bụ ihe na-ebelata nzaghachi nke usoro ahụ ji alụso ọrịa ọgụ, na-ebelata ihe nke enzymes nke na-akwalite mbufụt ma jiri ya mee ihe n'oge nke ọrịa ogbu na nkwonkwo.

Dabere na FDA, enwere ike iji nchịkọta a mee ihe na ndị ọrịa toro eto na ụmụaka karịa afọ 2, nọrọ n'ụlọ ọgwụ ma chọọ ọgwụgwọ na ikuku oxygen ma ọ bụ nke ikuku.

12. Ọpụpụ-CD24

EXO-CD24 bụ ọgwụ egosiri maka ọgwụgwọ megide ọrịa cancer ovarian ma nwee ike ịgwọ 29 nke ndị ọrịa 30 na COVID-19. Otú ọ dị, a ka na-emekwu ọmụmụ ihe, ya na ọnụ ọgụgụ buru ibu nke ndị mmadụ, na ebumnuche nke ịchọpụta ma ọgwụ a ọ ga-adị irè n'ịgwọ ọrịa ahụ na ọgwụ a na-ewere dị mma maka ojiji.

Ngwọta ọgwụgwọ maka ọgwụgwọ coronavirus

Ka ọ dị ugbu a, enweghị ọgwụgwọ ndị sitere n'okike iji kpochapụ coronavirus ma nyere aka gwọọ COVID-19, agbanyeghị, WHO ghotara na osisi ahụ Artemisia kwaa nwere ike inye aka na ọgwụgwọ ^[11], ọkachasị n’ebe enwere ike ịnweta ọgwụ ma tinyekwa ihe ọkụkụ na ọgwụ ọdịnala, dịka ọ dị na mpaghara dị iche iche n’Africa.

Akwụkwọ nke osisi Artemisia kwaa A na-ejikarị ya eme ihe n'Africa iji nyere aka ịgwọ ịba, ya mere, WHO ghọtara na ọ dị mkpa maka ọmụmụ ihe iji ghọta ma enwere ike iji osisi ahụ na ọgwụgwọ nke COVID-19, ebe ọ bụ na ụfọdụ ọgwụ sịntetik megide ịba egosipụtakwala nsonaazụ na-ekwe nkwa .

N'agbanyeghị nke ahụ, ọ dị mkpa icheta na ojiji nke osisi ahụ akwadobeghị COVID-19 nakwa na ọ dị mkpa nyocha ọzọ.