Lactic Acidosis: Ihe I Kwesịrị Knowmara

Ndinaya

• Kedu ihe mgbaàmà?
• Kedu ihe kpatara ya?
• Ọrịa obi
• Ọrịa siri ike (sepsis)
• HIV
• Ọrịa cancer
• Ọrịa afọ ụkwụ (eriri afọ)
• Acetaminophen were
• A alcoholụrụma na-adịghị ala ala
• Nnukwu mmega ahụ ma ọ bụ mmega ahụ
• Lactic acidosis na-arịa ọrịa shuga
• Kedu ka esi amata ya?
• Kedu usoro nhọrọ?
• Kedu ihe bụ echiche ya?
• Na-egbochi lactic acidosis

Gịnị bụ lactic acidosis?

Lactic acidosis bụ ụdị metabolic acidosis nke na-amalite mgbe mmadụ mebigara ma ọ bụ mebie lactic acid, na ahụ ha enweghị ike ịhazigharị mgbanwe ndị a.

Ndị nwere lactic acidosis nwere (na mgbe ụfọdụ akụrụ ha) na-enwe ike iwepu acid dị ukwuu na ahụ ha. Ọ bụrụ na acid lactic na-eto n'ime ahụ ngwa ngwa karịa ka ewepụ ya, ogo acidity dị na mmiri - dịka ọbara - ịgba.

Nke a buildup nke acid na-eme ka ahaghị nhata na pH ahụ, nke kwesịrị ịbụ ntakịrị alkaline kama acidic. E nwere ụdị ole na ole nke acidosis.

Lactic acid buildup na-eme mgbe enweghi oxygen zuru oke na akwara iji mebie glucose na glycogen. A na-akpọ nke a anaerobic metabolism.

E nwere ụdị abụọ nke lactic acid: L-lactate na D-lactate. Imirikiti ụdị lactic acidosis na-akpata oke L-lactate.

E nwere ụdị abụọ nke lactic acidosis, Typedị A na Bdị B:

• Pịnye A lactic acidosis ihe kpatara hypoperfusion anụ ahụ na-akpata hypovolemia, nkụda obi, sepsis, ma ọ bụ ijide cardiopulmonary.
• Pịnye B lactic acidosis kpatara mmebi nke ịrụ ọrụ cellular na mpaghara akụkụ akụkụ nke anụ ahụ hypoperfusion.

Lactic acidosis nwere ọtụtụ ihe na-akpata ya ma enwere ike ịgwọ ya. Ma ọ bụrụ na a hapụghị ya, ọ nwere ike itinye ndụ gị egwu.

Kedu ihe mgbaàmà?

Ihe mgbaàmà nke lactic acidosis bụ ụdị nke ọtụtụ nsogbu ahụ ike. Ọ bụrụ na ị nwee otu n’ime mgbaàmà ndị a, ị ga-akpọtụrụ dọkịta gị ozugbo. Dọkịta gị nwere ike inye aka chọpụta ihe kpatara ya.

Ọtụtụ mgbaàmà nke lactic acidosis na-anọchite anya mberede ahụike:

• ume mkpụrụ osisi na-esi ísì ụtọ (nke nwere ike igosipụta nsogbu dị ukwuu nke ọrịa shuga, nke a na-akpọ ketoacidosis)
• mgbagwoju anya
• jaundice (acha ọbara ọbara ma ọ bụ nke ọcha n'anya)
• nsogbu iku ume ma ọ bụ emighị emi, iku ume ngwa ngwa

Ọ bụrụ na ịmara ma ọ bụ na-enyo enyo na ị nwere lactic acidosis ma nwee otu n'ime mgbaàmà ndị a, kpọọ 911 ma ọ bụ gaa na ụlọ mberede ozugbo.

Ihe mgbaàmà ndị ọzọ nke lactic acidosis gụnyere:

• ike ọgwụgwụ ma ọ bụ oké ike ọgwụgwụ
• mọzụlụ ma ọ bụ ihe mgbu
• ahụ adịghị ike
• mmetụta zuru oke nke ahụ erughị ala
• afọ mgbu ma ọ bụ ahụ erughị ala
• afọ ọsịsa
• ibelata agụụ
• isi ọwụwa
• ngwa ngwa obi

Kedu ihe kpatara ya?

Lactic acidosis nwere ọtụtụ ihe na-akpata ya, gụnyere nsị carbon monoxide, ọgbụgbọ, ọnya, na anwụrụ ọkụ. Fọdụ ihe kpatara ya gụnyere:

Ọrịa obi

Ọnọdụ ndị dị ka njide ejiri obi na nkụchi obi nwere ike belata ọbara na oxygen n'ime ahụ niile. Nke a nwere ike ịbawanye ogo lactic acid.

Ọrịa siri ike (sepsis)

Typedị ụdị ọrịa ọ bụla siri ike ma ọ bụ nke nje nwere ike ibute sepsis. Ndị nwere sepsis nwere ike ịnwe ọgwu na lactic acid, na-ebute mbenata ikuku oxygen.

HIV

Ngwá ọgwụ nje HIV, dị ka ndị na-emechi transcriptase na-agbanwe agbanwe, nwere ike ịgba ọkwa lactic acid. Ha nwekwara ike imebi imeju. Nke a na - eme ka ọ na - esiri ahụ ike ịhazi lactate.

Ọrịa cancer

Mkpụrụ ndụ cancer na-emepụta lactic acid. Nchịkọta nke lactic acid nwere ike mee ka mmadụ ghara ibu ibu ma ọrịa ahụ na-aga n’ihu.

Ọrịa afọ ụkwụ (eriri afọ)

Mgbe, ndị nwere mkpụmkpụ mkpụmkpụ nwere ike ịmịpụta nke D-lactic acid, nke nje na-akpata na obere eriri afọ. Ndị mmadụ nweela ịwa ahụ na ngwọ ịwa afọ nwekwara ike ị nweta D-lactic acidosis.

Acetaminophen were

Mgbe nile, iji acetaminophen (Tylenol) mgbe niile nwere ike ibute lactic acidosis, ọbụlagodi mgbe a na-ewere ya na usoro ọgwụgwọ. Nke a bụ n'ihi na ọ nwere ike ịkpata mkpokọta pyroglutamic acid n'ime ọbara.

A alcoholụrụma na-adịghị ala ala

Ụbiga mmanya na-aba n’anya ruo ogologo oge nwere ike iduga lactic acidosis na mmanya ketoacidosis. Mmiri ketoacidosis na-egbu egbu bụ ọnọdụ nwere ike ịnwụ ma ọ bụrụ na a hapụghị ya, mana enwere ike ịlụ ya na hydration (IV) hydration na glucose.

Mmanya na-aba n'anya na - abawanye ogo phosphate, nke na - emetụta akụrụ arụ. Nke a na-eme ka pH ahụ ahụ bụrụ acidic. Ọ bụrụ na ịnwe nsogbu ịbelata ị alcoholụ mmanya gị, ndị otu na-akwado nwere ike inye aka.

Nnukwu mmega ahụ ma ọ bụ mmega ahụ

Enwere ike ịmalite mmebi oge nke lactic acid site na mmega ahụ siri ike ma ọ bụrụ na ahụ gị enweghị oxygen zuru oke iji mebie glucose n'ime ọbara. Nke a nwere ike ibute mmetụta na-ere ọkụ na otu akwara ị na-eji. O nwekwara ike ime ka ọgbụgbọ na adịghị ike.

Lactic acidosis na-arịa ọrịa shuga

Otu ụdị ọgwụ na-arịa ọrịa shuga, nke a na-akpọ biguanides, nwere ike ibute ọtụtụ lactic acid.

Metformin (Glucophage) bụ otu n'ime ọgwụ ndị a. A na-eji ya agwọ shuga ma nwee ike ide ya maka ọnọdụ ndị ọzọ, dị ka akụrụ akụrụ. A na-ejikwa Metformin apụ-label iji na-agwọ ọrịa ọrịa polycystic ovarian.

Na ndị nwere ọrịa shuga, lactic acidosis nwere ike bụrụ ihe na-akpata nchegbu ma ọ bụrụ na ọrịa akụrụ dịkwa. Ọ bụrụ na ị nwere ọrịa shuga ma nwee mgbaàmà ọ bụla nke lactic acidosis, kpọọ 911 ma ọ bụ gaa na ụlọ mberede ozugbo.

Kedu ka esi amata ya?

A na - achọpụta lactic acidosis site na nyocha ọbara na - ebu ọnụ. Dọkịta gị nwere ike ịgwa gị ka ị ghara iri nri ma ọ bụ drinkụọ ihe ọ bụla maka awa 8 ruo 10 tupu ịle ule ahụ. Enwere ike ịgwa gị ka ị kwụsị ogo ọrụ gị n'ime awa ole na ole tupu ule ahụ.

N'oge ule ahụ, dọkịta gị nwere ike ịgwa gị ka ị ghara ịpị aka gị, n'ihi na nke a nwere ike ịmepụta ọkwa acid. Inye eriri na-agbanwe gburugburu ogwe aka nwekwara ike ịnwe nsonaazụ a.

Maka ebumnuche ndị a, a na-eme nyocha ọbara lactic acidosis mgbe ụfọdụ site na ịchọta akwara na azụ aka kama ogwe aka.

Kedu usoro nhọrọ?

Zọ kachasị mma iji gwọọ lactic acidosis bụ ịgwọ ihe kpatara ya. N'ihi nke a, ọgwụgwọ dịgasị iche iche.

Lactic acidosis mgbe ụfọdụ na-anọchite anya mberede ahụike. Nke a chọrọ ịgwọ mgbaàmà, n'agbanyeghị ihe kpatara ya. Oxygenba ụba oxygen na anụ ahụ na ịnye mmiri mmiri IV na-ejikarị belata ogo lactic acid.

Lactic acidosis nke mmega ahụ nwere ike ịgwọ n'ụlọ. Kwụsị ihe ị na-eme iji hydrate na izu ike, na-enyekarị aka. Ihe ọ drinksụ drinksụ egwuregwu na-agbanwe electrolyte, dị ka Gatorade, na-enyere aka na hydration, mana mmiri na-adịkarị mma.

Kedu ihe bụ echiche ya?

Dabere na ihe kpatara ya, ọgwụgwọ maka lactic acidosis na-ebutekarị mgbake zuru oke, ọkachasị ma ọ bụrụ na ọgwụgwọ bụ ozugbo. Mgbe ụfọdụ, akụrụ odida ma ọ bụ iku ume iku ume nwere ike ịkpata. Mgbe ahapụghị ya, lactic acidosis nwere ike ịnwụ.

Na-egbochi lactic acidosis

A na-ekpebikwa mgbochi Lactic acidosis site na ihe kpatara ya. Ọ bụrụ na ị nwere ọrịa shuga, HIV, ma ọ bụ kansa, soro dọkịta gị kwurịta ọnọdụ gị na ọgwụ ịchọrọ.

Enwere ike igbochi Lactic acidosis site na mmega ahụ site na ịnwe hydrated na inye onwe gị ogologo oge izu ike n'etiti oge mmega ahụ.

Ọ dị ezigbo mkpa iji zere ị alcoholụbiga mmanya ókè. Soro dọkịta gị ma ọ bụ onye ndụmọdụ gị kwurịtara maka usoro mmezi na usoro mmemme iri na abụọ.