Nyocha LDH (Lactic Dehydrogenase): ihe ọ bụ na ihe nsonaazụ pụtara

Ndinaya

• Kedu ihe bụ ule
• Kedu ihe LDH dị elu pụtara?
• Kedu ihe nwere ike ịdị ala LDH?

LDH, a na-akpọkwa lactic dehydrogenase ma ọ bụ lactate dehydrogenase, bụ enzyme dị n'ime sel ndị na-ahụ maka metabolism nke glucose n'ime ahụ. Enwere ike ịchọta enzyme a n'ọtụtụ akụkụ na anụ ahụ yana, ya mere, nrịgo ya abụghị nke a kapịrị ọnụ, a na-atụ aro nyocha ndị ọzọ iji ruo nyocha.

N'ihe banyere nsonaazụ LDH gbanwere, na mgbakwunye na nyocha ndị ọzọ, dọkịta nwere ike igosi usoro nke LDH isoenzymes, nke elu ya nwere ike igosi mgbanwe ndị ọzọ:

• LDH-1, nke dị n'ime obi, mkpụrụ ndụ ọbara uhie na akụrụ;
• LDH-2, nke a pụrụ ịchọta n'ime obi, ruo n'ókè dị nta, na leukocytes;
• LDH-3, nke di na akpa ume;
• LDH-4, nke a hụrụ na placenta na pancreas;
• LDH-5, nke a na-ahụ n'ime imeju na akwara ọkpụkpụ.

Normalkpụrụ nkịtị nke lactate dehydrogenase nwere ike ịdị iche dịka ụlọ nyocha, a na-atụlekarị ya n'etiti 120 na 246 IU / L na ndị okenye.

Kedu ihe bụ ule

Nyocha LDH nwere ike inye iwu site na dọkịta dị ka nyocha oge niile, yana ule nyocha ndị ọzọ. Otú ọ dị, a na-egosipụtakarị ule a na nyocha nke nsogbu obi, na-arịọ ya na Creatinophosphokinase (CK) na troponin, ma ọ bụ nke mgbanwe hepatic, na-arịọkwa usoro ọgwụgwọ TGO / AST (Oxalacetic Transaminase / Aspartate Aminotransferase), TGP / ALT (Glutamic Pyruvic Transaminase / Alanine Aminotransferase) na GGT (gamma glutamyl transferase). Mara ule ndị ọzọ na-enyocha imeju.

Iji lee ule ọtụtụ oge ọ dịghị mkpa ibu ọnụ ma ọ bụ ụdị nkwadebe ọ bụla ọzọ, agbanyeghị ụfọdụ ụlọ nyocha na-egosi na ọ dị mkpa na onye ahụ dịkarịa ala elekere 4 na-ebu ọnụ. Ya mere, tupu ị mee nyocha ahụ, ọ dị mkpa ịgwa ụlọ nyocha banyere usoro kwesịrị ekwesị, na mgbakwunye na ịkọwa ojiji nke ọgwụ.

Kedu ihe LDH dị elu pụtara?

Mmụba nke LDH na-egosipụtakarị mmebi nke akụkụ ahụ ma ọ bụ anụ ahụ. Nke a bụ n'ihi na ihe na-akpata mmebi nke mkpụrụ ndụ, a na-ahapụ LDH dị n'ime sel ndị ahụ ma na-ekesa n'ọbara ya, a na-enyocha nyocha ya site na nyocha ọbara. Ọnọdụ ndị bụ isi nke mmụba na LDH nwere ike ịhụ bụ:

• Megaloblastic anaemia;
• Carcinoma;
• Septic ujo;
• Infarction;
• Hemolytic anaemia;
• Ọrịa leukemia;
• Mononucleosis;
• Patba ọcha n'anya;
• Obibi jaundice;
• Cirrhosis.

Ọnọdụ ụfọdụ nwere ike ịbawanye ogo LDH, ọ bụghị ihe na-egosi ọrịa, ọkachasị ma ọ bụrụ na usoro nyocha ụlọ akwụkwọ ndị ọzọ achọrọ bụ ihe nkịtị. Fọdụ ọnọdụ ndị nwere ike igbanwe ogo LDH n'ọbara bụ mmega ahụ siri ike, iji ụfọdụ ọgwụ na afọ ime.

Kedu ihe nwere ike ịdị ala LDH?

Mbelata nke lactic dehydrogenase na ọbara adịghị abụkarị ihe kpatara nchegbu ma ọ nweghị metụtara ọrịa ọ bụghịkwa ihe kpatara nyocha. N'ọnọdụ ụfọdụ, mbelata nke LDH nwere ike ịbụ ihe metụtara oke vitamin C, enwere ike ịtụnye mgbanwe n'ọdịdị nri mmadụ.