Testosterone
Nnwale testosterone na-atụle oke hormone nwoke, testosterone, n'ọbara. Menmụ nwoke na ụmụ nwanyị mepụtara homonụ a.
Nnwale ahụ akọwapụtara n'isiokwu a na-atụle ọnụ ọgụgụ zuru ezu nke testosterone n'ime ọbara. Imirikiti testosterone n'ime ọbara ga-ejikọ na protein a na-akpọ hormone mmekọahụ na-ejikọta globulin (SHBG). Nnwale ọbara ọzọ nwere ike ịlele testosterone "n'efu". Otú ọ dị, ụdị ule a adịkarịghị ezigbo mma.
A na-ewepụta ihe nlele ọbara site na akwara. Oge kachasị mma maka ịmịnye ọbara bụ n'agbata elekere asaa nke ụtụtụ na elekere iri nke ụtụtụ. A na-achọkarị ihe nlele nke abụọ iji gosipụta nsonaazụ dị ala karịa atụmanya.
Onye nlekọta ahụike nwere ike ịdụ gị ọdụ ka ị kwụsị ị medicinesụ ọgwụ nwere ike ịmetụta ule ahụ.
May nwere ike ịnwe obere ogwu ma ọ bụ gbaa mgbe etinyere agịga ahụ. Enwere ike ịtamu ụfọdụ mgbe emechara.
Enwere ike ime ule a ma ọ bụrụ na ị nwere mgbaàmà nke mmepụta nke hormone nwoke na-adịghị mma (androgen).
N'ime ụmụ nwoke, testicles na-emepụta ọtụtụ testosterone n'ime ahụ. A na-enyochakarị ọkwa iji nyochaa ihe ịrịba ama nke testosterone na-adịghị ahụkebe dịka:
- Oge mmalite ma ọ bụ n'oge uto (na ụmụ nwoke)
- Enweghi ike, mmekorita erectile, enweghi obi uto nke inwe mmekorita, ichoro nke okpukpu (n'ime mmadu)
N'ime ụmụ nwanyị, ovaries na-emepụta ọtụtụ testosterone. Akụkụ adrenal nwekwara ike ịmepụta ọtụtụ androgens ndị ọzọ gbanwere testosterone. A na-enyochakarị ọkwa iji nyochaa akara nke ogo testosterone dị elu, dị ka:
- Acne, mmanu mmanu
- Gbanwee n’olu okwu
- Mbelata nke ara
- Nwebiga ntutu dị ukwuu (ọchịchịrị, ntutu dị nro na ajị agba, ajị agba, nkuchi, obi, akwara, apata ụkwụ dị n'ime)
- Ọnụ kistitos toro eto
- Oge ezumike oge ma ọ bụ na-anọghị
- Baldị nkwọcha ụmụ nwoke ma ọ bụ ntutu isi
Measurekpụrụ nkịtị maka ule ndị a:
- Nwoke: 300 ka 1,000 nanogram kwa deciliter (ng / dL) ma ọ bụ 10 ruo 35 nanomoles kwa lita (nmol / L)
- Nwanyi: 15 ka 70 ng / dL ma obu 0.5 rue 2.4 nmol / L
Ihe atụ ndị dị n'elu bụ nha nkịtị maka nsonaazụ maka ule ndị a. Usoro ntanetị dị iche iche nwere ike ịdịtụ iche n'etiti ụlọ nyocha dị iche iche. Lafọdụ labs na-eji nha dị iche iche ma ọ bụ nwalee ụdị dị iche iche. Gwa onye na - enye gị ọrụ gbasara ihe nyocha gị pụtara.
Healthfọdụ ọnọdụ ahụike, ọgwụ, ma ọ bụ mmerụ ahụ nwere ike ibute testosterone dị ala. Ọkwa Testosterone na-adabakwa na afọ. Low testosterone nwere ike imetụta agụụ mmekọahụ, ọnọdụ, na akwara akwara na ụmụ nwoke.
Mbelata mkpokọta testosterone nwere ike ịbụ:
- Ọrịa na-adịghị ala ala
- Pituitary gland anaghị emepụta oke ma ọ bụ homonụ ya niile
- Nsogbu na mpaghara ụbụrụ nke na-achịkwa homonụ (hypothalamus)
- Ọrụ obere thyroid
- Oge uto
- Ọrịa nke testicles (trauma, cancer, ọrịa, dịghịzi, iron bufee)
- Ọrịa na-adịghị mma nke mkpụrụ ndụ pituitary nke na-emepụta ọtụtụ hormone prolactin
- Oke abụba (oke ibu)
- Nsogbu ihi ụra (ụra ụra na-egbochi)
- Nsogbu na-adịghị ala ala site na mgbatị dị ukwuu (ọrịa overtraining)
Ọnụ ọgụgụ zuru ezu nke testosterone nwere ike ịbụ n'ihi:
- Iguzogide ihe nke homonụ nwoke (androgen eguzogide)
- Tumo nke ovaries
- Ọrịa cancer nke ule
- Ọrịa adrenal hyperplasia
- Akingakingụ ọgwụ ma ọ bụ ọgwụ na-eme ka ogo testosterone (gụnyere ụfọdụ mgbakwunye)
Ọbara testosterone
Rey RA, Josso N. Diagnosis na ọgwụgwọ nke nsogbu nke mmepe mmekọahụ. Na: Jameson JL, De Groot LJ, de Kretser DM, et al, ndị ọzọ. Endocrinology: Okenye na Ọrịa edimụaka. Nke 7. Philadelphia, PA: Elsevier Saunders; 2016: isi 119.
Rosenfield RL, Barnes RB, Ehrmann DA. Hyperandrogenism, hirsutism, na ọrịa polycystic ovary. Na: Jameson JL, De Groot LJ, de Kretser DM, et al, ndị ọzọ. Endocrinology: Okenye na Ọrịa edimụaka. Nke 7. Philadelphia, PA: Elsevier Saunders; 2016: isi 133.
Swerdloff RS, Wang C. Ule na nwoke hypogonadism, infertility, na enweghi mmekorita nwoke na nwanyi. Na: Goldman L, Schafer AI, eds. Ọgwụ Goldman-Cecil. Nke 26th. Philadelphia, PA: Elsevier; 2020: isi 221.